These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

537 related articles for article (PubMed ID: 22941933)

  • 1. Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.
    Mendez G; Cilli D; Berardinelli F; Viganotti M; Ascenzi P; Tanzarella C; Antoccia A; di Masi A
    IUBMB Life; 2012 Oct; 64(10):853-61. PubMed ID: 22941933
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hsp90α regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks.
    Pennisi R; Antoccia A; Leone S; Ascenzi P; di Masi A
    FEBS J; 2017 Aug; 284(15):2378-2395. PubMed ID: 28631426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
    Cerosaletti K; Concannon P
    J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation.
    Cilli D; Mirasole C; Pennisi R; Pallotta V; D'Alessandro A; Antoccia A; Zolla L; Ascenzi P; di Masi A
    PLoS One; 2014; 9(12):e114651. PubMed ID: 25485873
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The R215W mutation in NBS1 impairs gamma-H2AX binding and affects DNA repair: molecular bases for the severe phenotype of 657del5/R215W Nijmegen breakage syndrome patients.
    di Masi A; Viganotti M; Polticelli F; Ascenzi P; Tanzarella C; Antoccia A
    Biochem Biophys Res Commun; 2008 May; 369(3):835-40. PubMed ID: 18328813
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.
    Waltes R; Kalb R; Gatei M; Kijas AW; Stumm M; Sobeck A; Wieland B; Varon R; Lerenthal Y; Lavin MF; Schindler D; Dörk T
    Am J Hum Genet; 2009 May; 84(5):605-16. PubMed ID: 19409520
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Active role for nibrin in the kinetics of atm activation.
    Cerosaletti K; Wright J; Concannon P
    Mol Cell Biol; 2006 Mar; 26(5):1691-9. PubMed ID: 16478990
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.
    Stracker TH; Morales M; Couto SS; Hussein H; Petrini JH
    Nature; 2007 May; 447(7141):218-21. PubMed ID: 17429352
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular basis of ataxia telangiectasia and related diseases.
    Ball LG; Xiao W
    Acta Pharmacol Sin; 2005 Aug; 26(8):897-907. PubMed ID: 16038621
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage.
    Lee JH; Xu B; Lee CH; Ahn JY; Song MS; Lee H; Canman CE; Lee JS; Kastan MB; Lim DS
    Mol Cancer Res; 2003 Jul; 1(9):674-81. PubMed ID: 12861053
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling.
    Yamauchi M; Oka Y; Yamamoto M; Niimura K; Uchida M; Kodama S; Watanabe M; Sekine I; Yamashita S; Suzuki K
    DNA Repair (Amst); 2008 Mar; 7(3):405-17. PubMed ID: 18248856
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
    Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
    J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS.
    Shull ER; Lee Y; Nakane H; Stracker TH; Zhao J; Russell HR; Petrini JH; McKinnon PJ
    Genes Dev; 2009 Jan; 23(2):171-80. PubMed ID: 19171781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.
    Taylor AM; Groom A; Byrd PJ
    DNA Repair (Amst); 2004; 3(8-9):1219-25. PubMed ID: 15279810
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impact of heterozygous c.657-661del, p.I171V and p.R215W mutations in NBN on nibrin functions.
    Dzikiewicz-Krawczyk A; Mosor M; Januszkiewicz D; Nowak J
    Mutagenesis; 2012 May; 27(3):337-43. PubMed ID: 22131123
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.
    Lee JH; Paull TT
    Science; 2005 Apr; 308(5721):551-4. PubMed ID: 15790808
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.
    Lee JH; Paull TT
    Oncogene; 2007 Dec; 26(56):7741-8. PubMed ID: 18066086
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Importance of Germline and Somatic Alterations in Human
    Otahalova B; Volkova Z; Soukupova J; Kleiblova P; Janatova M; Vocka M; Macurek L; Kleibl Z
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982687
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation.
    Cerosaletti KM; Concannon P
    J Biol Chem; 2003 Jun; 278(24):21944-51. PubMed ID: 12679336
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.