These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 22944119)

  • 1. Comparison of the cytotoxic effects of enantiopure PPAPs, including nemorosone and clusianone.
    Simpkins NS; Holtrup F; Rodeschini V; Taylor JD; Wolf R
    Bioorg Med Chem Lett; 2012 Oct; 22(19):6144-7. PubMed ID: 22944119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Clusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death.
    Reis FH; Pardo-Andreu GL; Nuñez-Figueredo Y; Cuesta-Rubio O; Marín-Prida J; Uyemura SA; Curti C; Alberici LC
    Chem Biol Interact; 2014 Apr; 212():20-9. PubMed ID: 24491676
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adventures in bridgehead substitution chemistry: synthesis of polycyclic polyprenylated acylphloroglucinols (PPAPs).
    Simpkins NS
    Chem Commun (Camb); 2013 Feb; 49(11):1042-51. PubMed ID: 23229029
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Collective total synthesis of PPAPs: total synthesis of clusianone via intramolecular cyclopropanation.
    Uwamori M; Nakada M
    Nat Prod Commun; 2013 Jul; 8(7):955-9. PubMed ID: 23980429
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differentiation of nonconventional "carbanions"-the total synthesis of nemorosone and clusianone.
    Tsukano C; Siegel DR; Danishefsky SJ
    Angew Chem Int Ed Engl; 2007; 46(46):8840-4. PubMed ID: 17935090
    [No Abstract]   [Full Text] [Related]  

  • 6. Development of a strategy for the asymmetric synthesis of polycyclic polyprenylated acylphloroglucinols via N-amino cyclic carbamate hydrazones: application to the total synthesis of (+)-clusianone.
    Garnsey MR; Lim D; Yost JM; Coltart DM
    Org Lett; 2010 Nov; 12(22):5234-7. PubMed ID: 20977254
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of polyprenylated acylphloroglucinols using bridgehead lithiation: the total synthesis of racemic clusianone and a formal synthesis of racemic garsubellin A.
    Ahmad NM; Rodeschini V; Simpkins NS; Ward SE; Blake AJ
    J Org Chem; 2007 Jun; 72(13):4803-15. PubMed ID: 17530804
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The enantioselective total synthesis of (+)-clusianone.
    Horeischi F; Guttroff C; Plietker B
    Chem Commun (Camb); 2015 Feb; 51(12):2259-61. PubMed ID: 25563512
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Asymmetric total synthesis of (+)- and (-)-clusianone and (+)- and (-)-clusianone methyl enol ether via ACC alkylation and evaluation of their anti-HIV activity.
    Garnsey MR; Matous JA; Kwiek JJ; Coltart DM
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2406-9. PubMed ID: 21414776
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of (+/-)-clusianone: high-yielding bridgehead and diketone substitutions by regioselective lithiation of enol ether derivatives of bicyclo[3.3.1]nonane-2,4,9-triones.
    Rodeschini V; Ahmad NM; Simpkins NS
    Org Lett; 2006 Nov; 8(23):5283-5. PubMed ID: 17078698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The identification of a novel natural activator of p300 histone acetyltranferase provides new insights into the modulation mechanism of this enzyme.
    Dal Piaz F; Tosco A; Eletto D; Piccinelli AL; Moltedo O; Franceschelli S; Sbardella G; Remondelli P; Rastrelli L; Vesci L; Pisano C; De Tommasi N
    Chembiochem; 2010 Apr; 11(6):818-27. PubMed ID: 20373302
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New phenstatin-fatty acid conjugates: synthesis and evaluation.
    Chen J; Brown DP; Wang YJ; Chen ZS
    Bioorg Med Chem Lett; 2013 Sep; 23(18):5119-22. PubMed ID: 23932339
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regiodivergent Photocyclization of Dearomatized Acylphloroglucinols: Asymmetric Syntheses of (-)-Nemorosone and (-)-6-
    Wen S; Boyce JH; Kandappa SK; Sivaguru J; Porco JA
    J Am Chem Soc; 2019 Jul; 141(28):11315-11321. PubMed ID: 31264859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alpha,alpha'-annulation of 2,6-prenyl-substituted cyclohexanone derivatives with malonyl chloride: application to a short synthesis of (+/-)-clusianone. Formation and rearrangement of a biogenetic-like intermediate.
    Nuhant P; David M; Pouplin T; Delpech B; Marazano C
    Org Lett; 2007 Jan; 9(2):287-9. PubMed ID: 17217286
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bridgehead enolate or bridgehead organolithium? DFT calculations provide insights into a difficult bridgehead substitution reaction in the synthesis of the polycyclic polyprenylated acylphloroglucinol (PPAP) nemorosone.
    Hayes CJ; Simpkins NS
    Org Biomol Chem; 2013 Dec; 11(48):8458-62. PubMed ID: 24202405
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 7-
    Taylor WF; Yanez M; Moghadam SE; Moridi Farimani M; Soroury S; Ebrahimi SN; Tabefam M; Jabbarzadeh E
    Molecules; 2019 Dec; 24(23):. PubMed ID: 31816878
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetic resolution in a bridgehead lithiation mediated by a chiral bis-lithium amide: assignment of the absolute configuration of clusianone.
    Rodeschini V; Simpkins NS; Wilson C
    J Org Chem; 2007 May; 72(11):4265-7. PubMed ID: 17465570
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxic activity of new racemic and optically active N-phosphonoalkyl bicyclic β-amino acids against human malignant cell lines.
    Todorov PT; Wesselinova DW; Pavlov ND; Martinez J; Calmes M; Naydenova ED
    Amino Acids; 2012 Oct; 43(4):1445-50. PubMed ID: 22237947
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quinazoline-sulfonamides as potential antitumor agents: synthesis and biological testing.
    Alafeefy AM; Alqasoumi SI; Ashour AE; Alshebly MM
    J Enzyme Inhib Med Chem; 2013 Apr; 28(2):375-83. PubMed ID: 22468752
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and antitumor activity of bicyclo[3.3.1]nonenol derivatives.
    Geirsson JK; Jonsson S; Valgeirsson J
    Bioorg Med Chem; 2004 Nov; 12(21):5563-9. PubMed ID: 15465333
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.