BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

562 related articles for article (PubMed ID: 22944335)

  • 1. O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation.
    Mao F; Huang L; Luo Z; Liu A; Lu C; Xie Z; Li X
    Bioorg Med Chem; 2012 Oct; 20(19):5884-92. PubMed ID: 22944335
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
    Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids.
    Huang L; Su T; Shan W; Luo Z; Sun Y; He F; Li X
    Bioorg Med Chem; 2012 May; 20(9):3038-48. PubMed ID: 22472046
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
    Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
    Xie SS; Wang XB; Li JY; Yang L; Kong LY
    Eur J Med Chem; 2013 Jun; 64():540-53. PubMed ID: 23685572
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
    Li SY; Wang XB; Xie SS; Jiang N; Wang KD; Yao HQ; Sun HB; Kong LY
    Eur J Med Chem; 2013 Nov; 69():632-46. PubMed ID: 24095756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Shan WJ; Huang L; Zhou Q; Meng FC; Li XS
    Eur J Med Chem; 2011 Dec; 46(12):5885-93. PubMed ID: 22019228
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
    Fernández-Bachiller MI; Pérez C; González-Muñoz GC; Conde S; López MG; Villarroya M; García AG; Rodríguez-Franco MI
    J Med Chem; 2010 Jul; 53(13):4927-37. PubMed ID: 20545360
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Benzenediol-berberine hybrids: multifunctional agents for Alzheimer's disease.
    Jiang H; Wang X; Huang L; Luo Z; Su T; Ding K; Li X
    Bioorg Med Chem; 2011 Dec; 19(23):7228-35. PubMed ID: 22041172
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
    Tang H; Zhao LZ; Zhao HT; Huang SL; Zhong SM; Qin JK; Chen ZF; Huang ZS; Liang H
    Eur J Med Chem; 2011 Oct; 46(10):4970-9. PubMed ID: 21871694
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids.
    Benchekroun M; Bartolini M; Egea J; Romero A; Soriano E; Pudlo M; Luzet V; Andrisano V; Jimeno ML; López MG; Wehle S; Gharbi T; Refouvelet B; de Andrés L; Herrera-Arozamena C; Monti B; Bolognesi ML; Rodríguez-Franco MI; Decker M; Marco-Contelles J; Ismaili L
    ChemMedChem; 2015 Mar; 10(3):523-39. PubMed ID: 25537267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.
    Fernández-Bachiller MI; Pérez C; Monjas L; Rademann J; Rodríguez-Franco MI
    J Med Chem; 2012 Feb; 55(3):1303-17. PubMed ID: 22243648
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
    Chao X; He X; Yang Y; Zhou X; Jin M; Liu S; Cheng Z; Liu P; Wang Y; Yu J; Tan Y; Huang Y; Qin J; Rapposelli S; Pi R
    Bioorg Med Chem Lett; 2012 Oct; 22(20):6498-502. PubMed ID: 22981331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, Aβ aggregation, and β-secretase.
    Sun Q; Peng DY; Yang SG; Zhu XL; Yang WC; Yang GF
    Bioorg Med Chem; 2014 Sep; 22(17):4784-91. PubMed ID: 25088549
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E; Sadeghpour H; Nadri H; Sakhteman A; Tüylü Küçükkılınç T; Miri R; Edraki N
    Bioorg Chem; 2019 Aug; 89():103006. PubMed ID: 31158577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and evaluation of novel 5,6,7-trimethoxyflavone-6-chlorotacrine hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Liao S; Deng H; Huang S; Yang J; Wang S; Yin B; Zheng T; Zhang D; Liu J; Gao G; Ma J; Deng Z
    Bioorg Med Chem Lett; 2015 Apr; 25(7):1541-5. PubMed ID: 25724825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
    Keri RS; Quintanova C; Marques SM; Esteves AR; Cardoso SM; Santos MA
    Bioorg Med Chem; 2013 Aug; 21(15):4559-69. PubMed ID: 23768661
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tacrine-(hydroxybenzoyl-pyridone) hybrids as potential multifunctional anti-Alzheimer's agents: AChE inhibition, antioxidant activity and metal chelating capacity.
    Chand K; Alsoghier HM; Chaves S; Santos MA
    J Inorg Biochem; 2016 Oct; 163():266-277. PubMed ID: 27235273
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.