BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 22945237)

  • 21. Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
    Alachkar H; Mutonga MB; Metzeler KH; Fulton N; Malnassy G; Herold T; Spiekermann K; Bohlander SK; Hiddemann W; Matsuo Y; Stock W; Nakamura Y
    Oncotarget; 2014 Dec; 5(23):12371-82. PubMed ID: 25365263
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase in Adrenocortical Carcinoma.
    Kiseljak-Vassiliades K; Zhang Y; Kar A; Razzaghi R; Xu M; Gowan K; Raeburn CD; Albuja-Cruz M; Jones KL; Somerset H; Fishbein L; Leong S; Wierman ME
    Endocrinology; 2018 Jul; 159(7):2532-2544. PubMed ID: 29790920
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of UBE2C as hub gene in driving prostate cancer by integrated bioinformatics analysis.
    Wang Y; Wang J; Tang Q; Ren G
    PLoS One; 2021; 16(2):e0247827. PubMed ID: 33630978
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers.
    Ganguly R; Hong CS; Smith LG; Kornblum HI; Nakano I
    Mol Cancer Ther; 2014 Jun; 13(6):1393-8. PubMed ID: 24795222
    [TBL] [Abstract][Full Text] [Related]  

  • 25. High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo.
    Ikeda Y; Sato S; Yabuno A; Shintani D; Ogasawara A; Miwa M; Zewde M; Miyamoto T; Fujiwara K; Nakamura Y; Hasegawa K
    J Gynecol Oncol; 2020 Nov; 31(6):e93. PubMed ID: 33078598
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells.
    Nakano I; Masterman-Smith M; Saigusa K; Paucar AA; Horvath S; Shoemaker L; Watanabe M; Negro A; Bajpai R; Howes A; Lelievre V; Waschek JA; Lazareff JA; Freije WA; Liau LM; Gilbertson RJ; Cloughesy TF; Geschwind DH; Nelson SF; Mischel PS; Terskikh AV; Kornblum HI
    J Neurosci Res; 2008 Jan; 86(1):48-60. PubMed ID: 17722061
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Arrestin-3 interaction with maternal embryonic leucine-zipper kinase.
    Perry NA; Fialkowski KP; Kaoud TS; Kaya AI; Chen AL; Taliaferro JM; Gurevich VV; Dalby KN; Iverson TM
    Cell Signal; 2019 Nov; 63():109366. PubMed ID: 31352007
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Maternal embryonic leucine zipper kinase in tumor cells and tumor microenvironment: An emerging player and promising therapeutic opportunity.
    Tang BF; Yan RC; Wang SW; Zeng ZC; Du SS
    Cancer Lett; 2023 Apr; 560():216126. PubMed ID: 36933780
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition of maternal embryonic leucine zipper kinase with OTSSP167 displays potent anti-leukemic effects in chronic lymphocytic leukemia.
    Zhang Y; Zhou X; Li Y; Xu Y; Lu K; Li P; Wang X
    Oncogene; 2018 Oct; 37(41):5520-5533. PubMed ID: 29895969
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
    Chlenski A; Park C; Dobratic M; Salwen HR; Budke B; Park JH; Miller R; Applebaum MA; Wilkinson E; Nakamura Y; Connell PP; Cohn SL
    Mol Cancer Ther; 2019 Mar; 18(3):507-516. PubMed ID: 30674566
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Suppressor of activator protein-1 regulated by interferon expression in prostate cancer tissues and cells.
    Zhang S; Rong P; Chen Q; Wang W
    Life Sci; 2019 Sep; 232():116626. PubMed ID: 31276688
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Genome-wide effects of MELK-inhibitor in triple-negative breast cancer cells indicate context-dependent response with p53 as a key determinant.
    Simon M; Mesmar F; Helguero L; Williams C
    PLoS One; 2017; 12(2):e0172832. PubMed ID: 28235006
    [TBL] [Abstract][Full Text] [Related]  

  • 33. MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
    Ren L; Deng B; Saloura V; Park JH; Nakamura Y
    Oncol Rep; 2019 Apr; 41(4):2540-2548. PubMed ID: 30720113
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification of potential therapeutic targets in prostate cancer through a cross-species approach.
    Jurmeister S; Ramos-Montoya A; Sandi C; Pértega-Gomes N; Wadhwa K; Lamb AD; Dunning MJ; Attig J; Carroll JS; Fryer LG; Felisbino SL; Neal DE
    EMBO Mol Med; 2018 Mar; 10(3):. PubMed ID: 29437778
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Expression profiles of androgen independent bone metastatic prostate cancer cells indicate up-regulation of the putative serine-threonine kinase GS3955.
    Bisoffi M; Klima I; Gresko E; Durfee PN; Hines WC; Griffith JK; Studer UE; Thalmann GN
    J Urol; 2004 Sep; 172(3):1145-50. PubMed ID: 15311059
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 5-Keto-3-cyano-2,4-diaminothiophenes as selective maternal embryonic leucine zipper kinase inhibitors.
    Boutard N; Sabiniarz A; Czerwińska K; Jarosz M; Cierpich A; Kolasińska E; Wiklik K; Gluza K; Commandeur C; Buda A; Stasiowska A; Bobowska A; Galek M; Fabritius CH; Bugaj M; Palacz E; Mazan A; Zarębski A; Krawczyńska K; Żurawska M; Zawadzki P; Milik M; Węgrzyn P; Dobrzańska M; Brzózka K; Kowalczyk P
    Bioorg Med Chem Lett; 2019 Feb; 29(4):607-613. PubMed ID: 30626559
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation.
    Nakano I; Paucar AA; Bajpai R; Dougherty JD; Zewail A; Kelly TK; Kim KJ; Ou J; Groszer M; Imura T; Freije WA; Nelson SF; Sofroniew MV; Wu H; Liu X; Terskikh AV; Geschwind DH; Kornblum HI
    J Cell Biol; 2005 Aug; 170(3):413-27. PubMed ID: 16061694
    [TBL] [Abstract][Full Text] [Related]  

  • 38. BUB1B Promotes Proliferation of Prostate Cancer via Transcriptional Regulation of MELK.
    Tian JH; Mu LJ; Wang MY; Zeng J; Long QZ; Guan B; Wang W; Jiang YM; Bai XJ; Du YF
    Anticancer Agents Med Chem; 2020; 20(9):1140-1146. PubMed ID: 31893996
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner.
    Gu C; Banasavadi-Siddegowda YK; Joshi K; Nakamura Y; Kurt H; Gupta S; Nakano I
    Stem Cells; 2013 May; 31(5):870-81. PubMed ID: 23339114
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Expression of Maternal Embryonic Leucine Zipper Kinase (MELK) Correlates to Malignant Potentials in Hepatocellular Carcinoma.
    Hiwatashi K; Ueno S; Sakoda M; Iino S; Minami K; Yonemori K; Nishizono Y; Kurahara H; Mataki Y; Maemura K; Shinchi H; Natsugoe S
    Anticancer Res; 2016 Oct; 36(10):5183-5188. PubMed ID: 27798878
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.