BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 22945423)

  • 1. Aberrant methylation of the PTCH1 gene promoter region in aberrant crypt foci.
    Peng L; Hu J; Li S; Wang Z; Xia B; Jiang B; Li B; Zhang Y; Wang J; Wang X
    Int J Cancer; 2013 Jan; 132(2):E18-25. PubMed ID: 22945423
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas.
    Gialmanidis IP; Bravou V; Amanetopoulou SG; Varakis J; Kourea H; Papadaki H
    Lung Cancer; 2009 Oct; 66(1):64-74. PubMed ID: 19200615
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sonic hedgehog and Gli1 expression predict outcome in resected pancreatic adenocarcinoma.
    Maréchal R; Bachet JB; Calomme A; Demetter P; Delpero JR; Svrcek M; Cros J; Bardier-Dupas A; Puleo F; Monges G; Hammel P; Louvet C; Paye F; Bachelier P; Le Treut YP; Vaillant JC; Sauvanet A; André T; Salmon I; Devière J; Emile JF; Van Laethem JL
    Clin Cancer Res; 2015 Mar; 21(5):1215-24. PubMed ID: 25552484
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.
    Decker S; Zirlik K; Djebatchie L; Hartmann D; Ihorst G; Schmitt-Graeff A; Herchenbach D; Jumaa H; Warmuth M; Veelken H; Dierks C
    Blood; 2012 Jan; 119(4):997-1007. PubMed ID: 22130798
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells.
    Spicer LJ; Sudo S; Aad PY; Wang LS; Chun SY; Ben-Shlomo I; Klein C; Hsueh AJ
    Reproduction; 2009 Aug; 138(2):329-39. PubMed ID: 19433502
    [TBL] [Abstract][Full Text] [Related]  

  • 7. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched.
    Busch AM; Galimberti F; Nehls KE; Roengvoraphoj M; Sekula D; Li B; Guo Y; Direnzo J; Fiering SN; Spinella MJ; Robbins DJ; Memoli VA; Freemantle SJ; Dmitrovsky E
    Cancer Biol Ther; 2014 Apr; 15(4):463-72. PubMed ID: 24496080
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of hedgehog pathway components is associated with bladder cancer progression and clinical outcome.
    He HC; Chen JH; Chen XB; Qin GQ; Cai C; Liang YX; Han ZD; Dai QS; Chen YR; Zeng GH; Zhu JG; Jiang FN; Zhong WD
    Pathol Oncol Res; 2012 Apr; 18(2):349-55. PubMed ID: 21861243
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas.
    Bian YH; Huang SH; Yang L; Ma XL; Xie JW; Zhang HW
    World J Gastroenterol; 2007 Mar; 13(11):1659-65. PubMed ID: 17461467
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
    Trazzi S; Mitrugno VM; Valli E; Fuchs C; Rizzi S; Guidi S; Perini G; Bartesaghi R; Ciani E
    Hum Mol Genet; 2011 Apr; 20(8):1560-73. PubMed ID: 21266456
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro.
    Wu JY; Xu XF; Xu L; Niu PQ; Wang F; Hu GY; Wang XP; Guo CY
    Hepatogastroenterology; 2011; 58(110-111):1511-8. PubMed ID: 21940310
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hedgehog signaling pathway is inactive in colorectal cancer cell lines.
    Chatel G; Ganeff C; Boussif N; Delacroix L; Briquet A; Nolens G; Winkler R
    Int J Cancer; 2007 Dec; 121(12):2622-7. PubMed ID: 17683069
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expressions of sonic hedgehog, patched, smoothened and Gli-1 in human intestinal stromal tumors and their correlation with prognosis.
    Yoshizaki A; Nakayama T; Naito S; Wen CY; Sekine I
    World J Gastroenterol; 2006 Sep; 12(35):5687-91. PubMed ID: 17007023
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.
    Lee SJ; Do IG; Lee J; Kim KM; Jang J; Sohn I; Kang WK
    Target Oncol; 2013 Dec; 8(4):271-80. PubMed ID: 23371028
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway.
    Wang TP; Hsu SH; Feng HC; Huang RF
    Carcinogenesis; 2012 Jun; 33(6):1158-68. PubMed ID: 22461522
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
    Pritchard JI; Olson JM
    Cancer Genet Cytogenet; 2008 Jan; 180(1):47-50. PubMed ID: 18068533
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo.
    Guo J; Gao J; Li Z; Gong Y; Man X; Jin J; Wu H
    Cancer Lett; 2013 Oct; 339(2):185-94. PubMed ID: 23791879
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.
    Shahi MH; Afzal M; Sinha S; Eberhart CG; Rey JA; Fan X; Castresana JS
    BMC Cancer; 2010 Nov; 10():614. PubMed ID: 21059263
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of expression of DNA mismatch repair proteins in aberrant crypt foci identified in vivo by magnifying colonoscopy in subjects with hereditary nonpolyposic and sporadic colon rectal cancer.
    Ramírez-Ramírez MA; Sobrino-Cossío S; de la Mora-Levy JG; Hernández-Guerrero A; Macedo-Reyes Vde J; Maldonado-Martínez HA; Alonso-Larraga JO; Ramírez-Solis ME
    J Gastrointest Cancer; 2012 Jun; 43(2):209-14. PubMed ID: 21744313
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression and clinical significance of hedgehog signaling pathway related components in colorectal cancer.
    Wang H; Li YY; Wu YY; Nie YQ
    Asian Pac J Cancer Prev; 2012; 13(5):2319-24. PubMed ID: 22901214
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.