BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 22948873)

  • 1. Cosubstrate tolerance of the aminoglycoside resistance enzyme Eis from Mycobacterium tuberculosis.
    Chen W; Green KD; Garneau-Tsodikova S
    Antimicrob Agents Chemother; 2012 Nov; 56(11):5831-8. PubMed ID: 22948873
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Redesign of substrate specificity and identification of the aminoglycoside binding residues of Eis from Mycobacterium tuberculosis.
    Jennings BC; Labby KJ; Green KD; Garneau-Tsodikova S
    Biochemistry; 2013 Jul; 52(30):5125-32. PubMed ID: 23837529
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilis.
    Pricer RE; Houghton JL; Green KD; Mayhoub AS; Garneau-Tsodikova S
    Mol Biosyst; 2012 Oct; 8(12):3305-13. PubMed ID: 23090428
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis.
    Houghton JL; Biswas T; Chen W; Tsodikov OV; Garneau-Tsodikova S
    Chembiochem; 2013 Nov; 14(16):2127-35. PubMed ID: 24106131
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A random sequential mechanism of aminoglycoside acetylation by Mycobacterium tuberculosis Eis protein.
    Tsodikov OV; Green KD; Garneau-Tsodikova S
    PLoS One; 2014; 9(4):e92370. PubMed ID: 24699000
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes.
    Bassenden AV; Dumalo L; Park J; Blanchet J; Maiti K; Arya DP; Berghuis AM
    Sci Rep; 2021 Jun; 11(1):11614. PubMed ID: 34078922
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis.
    Pang AH; Green KD; Tsodikov OV; Garneau-Tsodikova S
    Methods Enzymol; 2023; 690():369-396. PubMed ID: 37858535
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Eis, a novel family of arylalkylamine N-acetyltransferase (EC 2.3.1.87).
    Pan Q; Zhao FL; Ye BC
    Sci Rep; 2018 Feb; 8(1):2435. PubMed ID: 29402941
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aminoglycoside multiacetylating activity of the enhanced intracellular survival protein from Mycobacterium smegmatis and its inhibition.
    Chen W; Green KD; Tsodikov OV; Garneau-Tsodikova S
    Biochemistry; 2012 Jun; 51(24):4959-67. PubMed ID: 22646013
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis.
    Green KD; Punetha A; Hou C; Garneau-Tsodikova S; Tsodikov OV
    ACS Infect Dis; 2019 Oct; 5(10):1772-1778. PubMed ID: 31433614
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes.
    Houghton JL; Green KD; Pricer RE; Mayhoub AS; Garneau-Tsodikova S
    J Antimicrob Chemother; 2013 Apr; 68(4):800-5. PubMed ID: 23233486
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative Study of Eis-like Enzymes from Pathogenic and Nonpathogenic Bacteria.
    Green KD; Pricer RE; Stewart MN; Garneau-Tsodikova S
    ACS Infect Dis; 2015 Jun; 1(6):272-83. PubMed ID: 27622743
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thermostable hexameric form of Eis (Rv2416c) protein of M. tuberculosis plays an important role for enhanced intracellular survival within macrophages.
    Ganaie AA; Lella RK; Solanki R; Sharma C
    PLoS One; 2011; 6(11):e27590. PubMed ID: 22110681
    [TBL] [Abstract][Full Text] [Related]  

  • 14. eis Promoter C14G and C15G Mutations Do Not Confer Kanamycin Resistance in Mycobacterium tuberculosis.
    Pholwat S; Stroup S; Heysell S; Ogarkov O; Zhdanova S; Ramakrishnan G; Houpt E
    Antimicrob Agents Chemother; 2016 Dec; 60(12):7522-7523. PubMed ID: 27736762
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potent 1,2,4-Triazino[5,6 b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis.
    Ngo HX; Green KD; Gajadeera CS; Willby MJ; Holbrook SYL; Hou C; Garzan A; Mayhoub AS; Posey JE; Tsodikov OV; Garneau-Tsodikova S
    ACS Infect Dis; 2018 Jun; 4(6):1030-1040. PubMed ID: 29601176
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correlating rrs and eis promoter mutations in clinical isolates of Mycobacterium tuberculosis with phenotypic susceptibility levels to the second-line injectables.
    Kambli P; Ajbani K; Nikam C; Sadani M; Shetty A; Udwadia Z; Georghiou SB; Rodwell TC; Catanzaro A; Rodrigues C
    Int J Mycobacteriol; 2016 Mar; 5(1):1-6. PubMed ID: 26927983
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis.
    Zaunbrecher MA; Sikes RD; Metchock B; Shinnick TM; Posey JE
    Proc Natl Acad Sci U S A; 2009 Nov; 106(47):20004-9. PubMed ID: 19906990
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB.
    Chen W; Biswas T; Porter VR; Tsodikov OV; Garneau-Tsodikova S
    Proc Natl Acad Sci U S A; 2011 Jun; 108(24):9804-8. PubMed ID: 21628583
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis.
    Willby MJ; Green KD; Gajadeera CS; Hou C; Tsodikov OV; Posey JE; Garneau-Tsodikova S
    ACS Chem Biol; 2016 Jun; 11(6):1639-46. PubMed ID: 27010218
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Study of aminoglycoside-nucleic acid interactions by an HPLC method.
    Constantinou-Kokotou T; Karikas G; Kokotos G
    Bioorg Med Chem Lett; 2001 Apr; 11(8):1015-8. PubMed ID: 11327578
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.