These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

931 related articles for article (PubMed ID: 22949014)

  • 1. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
    Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevåg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
    Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM
    J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors.
    Arnhold V; Boos J; Lanvers-Kaminsky C
    Cancer Chemother Pharmacol; 2016 Mar; 77(3):495-505. PubMed ID: 26781311
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Smoothened-independent activation of hedgehog signaling by rearranged during transfection promotes neuroblastoma cell proliferation and tumor growth.
    Ruan H; Luo H; Wang J; Ji X; Zhang Z; Wu J; Zhang X; Wu X
    Biochim Biophys Acta; 2016 Sep; 1860(9):1961-72. PubMed ID: 27316313
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hedgehog signaling drives cellular survival in human colon carcinoma cells.
    Mazumdar T; DeVecchio J; Shi T; Jones J; Agyeman A; Houghton JA
    Cancer Res; 2011 Feb; 71(3):1092-102. PubMed ID: 21135115
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting the hedgehog-glioma-associated oncogene homolog pathway inhibits bleomycin-induced lung fibrosis in mice.
    Moshai EF; Wémeau-Stervinou L; Cigna N; Brayer S; Sommé JM; Crestani B; Mailleux AA
    Am J Respir Cell Mol Biol; 2014 Jul; 51(1):11-25. PubMed ID: 24450438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
    Mazumdar T; Devecchio J; Agyeman A; Shi T; Houghton JA
    Cancer Res; 2011 Sep; 71(17):5904-14. PubMed ID: 21747117
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.
    Huang L; Walter V; Hayes DN; Onaitis M
    Clin Cancer Res; 2014 Mar; 20(6):1566-75. PubMed ID: 24423612
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
    Mazumdar T; DeVecchio J; Agyeman A; Shi T; Houghton JA
    Oncotarget; 2011 Aug; 2(8):638-45. PubMed ID: 21860067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of DNA damage following termination of Hedgehog (HH) survival signaling at the level of the GLI genes in human colon cancer.
    Agyeman A; Mazumdar T; Houghton JA
    Oncotarget; 2012 Aug; 3(8):854-68. PubMed ID: 23097684
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
    Kawabata N; Ijiri K; Ishidou Y; Yamamoto T; Nagao H; Nagano S; Maeda S; Komiya S; Setoguchi T
    Int J Oncol; 2011 Oct; 39(4):899-906. PubMed ID: 21674124
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma.
    Mori Y; Okumura T; Tsunoda S; Sakai Y; Shimada Y
    Oncology; 2006; 70(5):378-89. PubMed ID: 17179732
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis.
    Hu MC; Mo R; Bhella S; Wilson CW; Chuang PT; Hui CC; Rosenblum ND
    Development; 2006 Feb; 133(3):569-78. PubMed ID: 16396903
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.
    Gruber W; Hutzinger M; Elmer DP; Parigger T; Sternberg C; Cegielkowski L; Zaja M; Leban J; Michel S; Hamm S; Vitt D; Aberger F
    Oncotarget; 2016 Feb; 7(6):7134-48. PubMed ID: 26784250
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smoothened as a new therapeutic target for human osteosarcoma.
    Hirotsu M; Setoguchi T; Sasaki H; Matsunoshita Y; Gao H; Nagao H; Kunigou O; Komiya S
    Mol Cancer; 2010 Jan; 9():5. PubMed ID: 20067614
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gli as a novel therapeutic target in malignant pleural mesothelioma.
    Li H; Lui N; Cheng T; Tseng HH; Yue D; Giroux-Leprieur E; Do HT; Sheng Q; Jin JQ; Luh TW; Jablons DM; He B
    PLoS One; 2013; 8(3):e57346. PubMed ID: 23483902
    [TBL] [Abstract][Full Text] [Related]  

  • 17. LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway.
    Zhuang Z; Wang K; Cheng X; Qu X; Jiang B; Li Z; Luo J; Shao Z; Duan T
    PLoS One; 2013; 8(7):e67431. PubMed ID: 23861764
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HH/GLI signalling as a new therapeutic target for patients with oral squamous cell carcinoma.
    Yan M; Wang L; Zuo H; Zhang Z; Chen W; Mao L; Zhang P
    Oral Oncol; 2011 Jun; 47(6):504-9. PubMed ID: 21536478
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo.
    Guo J; Gao J; Li Z; Gong Y; Man X; Jin J; Wu H
    Cancer Lett; 2013 Oct; 339(2):185-94. PubMed ID: 23791879
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.
    Duan F; Lin M; Li C; Ding X; Qian G; Zhang H; Ge S; Fan X; Li J
    Cancer Biol Ther; 2014 May; 15(5):544-59. PubMed ID: 24553082
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 47.