These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

929 related articles for article (PubMed ID: 22949014)

  • 21. Gant61 ameliorates CCl
    Jiayuan S; Junyan Y; Xiangzhen W; Zuping L; Jian N; Baowei H; Lifang J
    Toxicol Appl Pharmacol; 2020 Jan; 387():114853. PubMed ID: 31816328
    [TBL] [Abstract][Full Text] [Related]  

  • 22. [The effects of Hedgehog-Gli 1 signaling pathway on proliferation and apoptosis of hepatic stellate cells].
    Liu J; Xu XF; Yang WJ
    Zhonghua Gan Zang Bing Za Zhi; 2009 Jan; 17(1):33-7. PubMed ID: 19203449
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Anti-cell growth and anti-cancer stem cell activities of the non-canonical hedgehog inhibitor GANT61 in triple-negative breast cancer cells.
    Koike Y; Ohta Y; Saitoh W; Yamashita T; Kanomata N; Moriya T; Kurebayashi J
    Breast Cancer; 2017 Sep; 24(5):683-693. PubMed ID: 28144905
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Vitamin D3 triggers antitumor activity through targeting hedgehog signaling in human renal cell carcinoma.
    Dormoy V; Béraud C; Lindner V; Coquard C; Barthelmebs M; Brasse D; Jacqmin D; Lang H; Massfelder T
    Carcinogenesis; 2012 Nov; 33(11):2084-93. PubMed ID: 22843547
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway.
    Ramaswamy B; Lu Y; Teng KY; Nuovo G; Li X; Shapiro CL; Majumder S
    Cancer Res; 2012 Oct; 72(19):5048-59. PubMed ID: 22875023
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
    Desch P; Asslaber D; Kern D; Schnidar H; Mangelberger D; Alinger B; Stoecher M; Hofbauer SW; Neureiter D; Tinhofer I; Aberger F; Hartmann TN; Greil R
    Oncogene; 2010 Sep; 29(35):4885-95. PubMed ID: 20603613
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
    Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
    Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Gli2 expression and human bladder transitional carcinoma cell invasiveness.
    Mechlin CW; Tanner MJ; Chen M; Buttyan R; Levin RM; Mian BM
    J Urol; 2010 Jul; 184(1):344-51. PubMed ID: 20488474
    [TBL] [Abstract][Full Text] [Related]  

  • 29. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
    Benvenuto M; Masuelli L; De Smaele E; Fantini M; Mattera R; Cucchi D; Bonanno E; Di Stefano E; Frajese GV; Orlandi A; Screpanti I; Gulino A; Modesti A; Bei R
    Oncotarget; 2016 Feb; 7(8):9250-70. PubMed ID: 26843616
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.
    Long J; Li B; Rodriguez-Blanco J; Pastori C; Volmar CH; Wahlestedt C; Capobianco A; Bai F; Pei XH; Ayad NG; Robbins DJ
    J Biol Chem; 2014 Dec; 289(51):35494-502. PubMed ID: 25355313
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The Hedgehog signalling pathway mediates drug response of MCF-7 mammosphere cells in breast cancer patients.
    He M; Fu Y; Yan Y; Xiao Q; Wu H; Yao W; Zhao H; Zhao L; Jiang Q; Yu Z; Jin F; Mi X; Wang E; Cui Z; Fu L; Chen J; Wei M
    Clin Sci (Lond); 2015 Nov; 129(9):809-22. PubMed ID: 26201092
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The prognostic significance and therapeutic potential of hedgehog signaling in intrahepatic cholangiocellular carcinoma.
    Tang L; Tan YX; Jiang BG; Pan YF; Li SX; Yang GZ; Wang M; Wang Q; Zhang J; Zhou WP; Dong LW; Wang HY
    Clin Cancer Res; 2013 Apr; 19(8):2014-24. PubMed ID: 23493353
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
    Lo WW; Wunder JS; Dickson BC; Campbell V; McGovern K; Alman BA; Andrulis IL
    Cancer; 2014 Feb; 120(4):537-47. PubMed ID: 24151134
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
    Graab U; Hahn H; Fulda S
    Oncotarget; 2015 Apr; 6(11):8722-35. PubMed ID: 25749378
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1.
    Götschel F; Berg D; Gruber W; Bender C; Eberl M; Friedel M; Sonntag J; Rüngeler E; Hache H; Wierling C; Nietfeld W; Lehrach H; Frischauf A; Schwartz-Albiez R; Aberger F; Korf U
    PLoS One; 2013; 8(6):e65403. PubMed ID: 23762360
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.
    Wellbrock J; Latuske E; Köhler J; Wagner K; Stamm H; Vettorazzi E; Vohwinkel G; Klokow M; Uibeleisen R; Ehm P; Riecken K; Loges S; Thol F; Schubert C; Amling M; Jücker M; Bokemeyer C; Heuser M; Krauter J; Fiedler W
    Clin Cancer Res; 2015 May; 21(10):2388-98. PubMed ID: 25745035
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Noncanonical regulation of the Hedgehog mediator GLI1 by c-MYC in Burkitt lymphoma.
    Yoon JW; Gallant M; Lamm ML; Iannaccone S; Vieux KF; Proytcheva M; Hyjek E; Iannaccone P; Walterhouse D
    Mol Cancer Res; 2013 Jun; 11(6):604-15. PubMed ID: 23525267
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells.
    Santini R; Vinci MC; Pandolfi S; Penachioni JY; Montagnani V; Olivito B; Gattai R; Pimpinelli N; Gerlini G; Borgognoni L; Stecca B
    Stem Cells; 2012 Sep; 30(9):1808-18. PubMed ID: 22730244
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 47.