BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 22949845)

  • 1. Effects of a buried cysteine-to-serine mutation on yeast triosephosphate isomerase structure and stability.
    Hernández-Santoyo A; Domínguez-Ramírez L; Reyes-López CA; González-Mondragón E; Hernández-Arana A; Rodríguez-Romero A
    Int J Mol Sci; 2012; 13(8):10010-10021. PubMed ID: 22949845
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conserved cysteine 126 in triosephosphate isomerase is required not for enzymatic activity but for proper folding and stability.
    González-Mondragón E; Zubillaga RA; Saavedra E; Chánez-Cárdenas ME; Pérez-Montfort R; Hernández-Arana A
    Biochemistry; 2004 Mar; 43(11):3255-63. PubMed ID: 15023076
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thermodynamic and kinetic destabilization of triosephosphate isomerase resulting from the mutation of conserved and non-conserved cysteines.
    Cruces-Ángeles ME; Cabrera N; Pérez-Montfort R; Reyes-López CA; Hernández-Arana A
    Protein Pept Lett; 2011 Dec; 18(12):1290-8. PubMed ID: 21707525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Species-specific inhibition of homologous enzymes by modification of nonconserved amino acids residues. The cysteine residues of triosephosphate isomerase.
    Garza-Ramos G; Pérez-Montfort R; Rojo-Domínguez A; de Gómez-Puyou MT; Gómez-Puyou A
    Eur J Biochem; 1996 Oct; 241(1):114-20. PubMed ID: 8898895
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystallography and site-directed mutagenesis of yeast triosephosphate isomerase: what can we learn about catalysis from a "simple" enzyme?
    Alber TC; Davenport RC; Giammona DA; Lolis E; Petsko GA; Ringe D
    Cold Spring Harb Symp Quant Biol; 1987; 52():603-13. PubMed ID: 3331346
    [No Abstract]   [Full Text] [Related]  

  • 6. Probing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis--distal effects on dimer stability.
    Samanta M; Banerjee M; Murthy MR; Balaram H; Balaram P
    FEBS J; 2011 Jun; 278(11):1932-43. PubMed ID: 21447068
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Key residues of loop 3 in the interaction with the interface residue at position 14 in triosephosphate isomerase from Trypanosoma brucei.
    Cabrera N; Hernández-Alcántara G; Mendoza-Hernández G; Gómez-Puyou A; Perez-Montfort R
    Biochemistry; 2008 Mar; 47(11):3499-506. PubMed ID: 18298085
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Triosephosphate isomerase from Plasmodium falciparum: the crystal structure provides insights into antimalarial drug design.
    Velanker SS; Ray SS; Gokhale RS; Suma S; Balaram H; Balaram P; Murthy MR
    Structure; 1997 Jun; 5(6):751-61. PubMed ID: 9261072
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure of the Plasmodium falciparum triosephosphate isomerase-phosphoglycolate complex in two crystal forms: characterization of catalytic loop open and closed conformations in the ligand-bound state.
    Parthasarathy S; Ravindra G; Balaram H; Balaram P; Murthy MR
    Biochemistry; 2002 Nov; 41(44):13178-88. PubMed ID: 12403619
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Segmental movement: definition of the structural requirements for loop closure in catalysis by triosephosphate isomerase.
    Sampson NS; Knowles JR
    Biochemistry; 1992 Sep; 31(36):8482-7. PubMed ID: 1390632
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM.
    Alahuhta M; Casteleijn MG; Neubauer P; Wierenga RK
    Acta Crystallogr D Biol Crystallogr; 2008 Feb; 64(Pt 2):178-88. PubMed ID: 18219118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution.
    Zhang Z; Sugio S; Komives EA; Liu KD; Knowles JR; Petsko GA; Ringe D
    Biochemistry; 1994 Mar; 33(10):2830-7. PubMed ID: 8130195
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power.
    Williams JC; Zeelen JP; Neubauer G; Vriend G; Backmann J; Michels PA; Lambeir AM; Wierenga RK
    Protein Eng; 1999 Mar; 12(3):243-50. PubMed ID: 10235625
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme.
    Pareek V; Samanta M; Joshi NV; Balaram H; Murthy MR; Balaram P
    Chembiochem; 2016 Apr; 17(7):620-9. PubMed ID: 26762569
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of the mutant yeast triosephosphate isomerase in which the catalytic base glutamic acid 165 is changed to aspartic acid.
    Joseph-McCarthy D; Rost LE; Komives EA; Petsko GA
    Biochemistry; 1994 Mar; 33(10):2824-9. PubMed ID: 7907502
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Active-Site Glu165 Activation in Triosephosphate Isomerase and Its Deprotonation Kinetics.
    Deng H; Dyer RB; Callender R
    J Phys Chem B; 2019 May; 123(19):4230-4241. PubMed ID: 31013084
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of water in the catalytic efficiency of triosephosphate isomerase.
    Zhang Z; Komives EA; Sugio S; Blacklow SC; Narayana N; Xuong NH; Stock AM; Petsko GA; Ringe D
    Biochemistry; 1999 Apr; 38(14):4389-97. PubMed ID: 10194358
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and functional perturbation of Giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region.
    Hernández-Alcántara G; Torres-Larios A; Enríquez-Flores S; García-Torres I; Castillo-Villanueva A; Méndez ST; de la Mora-de la Mora I; Gómez-Manzo S; Torres-Arroyo A; López-Velázquez G; Reyes-Vivas H; Oria-Hernández J
    PLoS One; 2013; 8(7):e69031. PubMed ID: 23894402
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Solution-state NMR investigations of triosephosphate isomerase active site loop motion: ligand release in relation to active site loop dynamics.
    Rozovsky S; Jogl G; Tong L; McDermott AE
    J Mol Biol; 2001 Jun; 310(1):271-80. PubMed ID: 11419952
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential inactivation of rabbit and yeast triosephosphate isomerase: effect of oxidations produced by chloramine-T.
    Zubillaga RA; Pérez-Montfort R; Gómez-Puyou A
    Arch Biochem Biophys; 1994 Sep; 313(2):328-36. PubMed ID: 8080280
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.