BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

566 related articles for article (PubMed ID: 22949930)

  • 21. The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease.
    Collins JM; King AE; Woodhouse A; Kirkcaldie MT; Vickers JC
    Exp Neurol; 2015 May; 267():219-29. PubMed ID: 25747037
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.
    Hansen HH; Fabricius K; Barkholt P; Kongsbak-Wismann P; Schlumberger C; Jelsing J; Terwel D; Termont A; Pyke C; Knudsen LB; Vrang N
    PLoS One; 2016; 11(7):e0158205. PubMed ID: 27421117
    [TBL] [Abstract][Full Text] [Related]  

  • 23. p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model.
    Martínez-Mármol R; Mohannak N; Qian L; Wang T; Gormal RS; Ruitenberg MJ; Vanhaesebroeck B; Coulson EJ; Meunier FA
    J Neurosci; 2019 Oct; 39(40):7976-7991. PubMed ID: 31363064
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice.
    Dewachter I; van Dorpe J; Spittaels K; Tesseur I; Van Den Haute C; Moechars D; Van Leuven F
    Exp Gerontol; 2000 Sep; 35(6-7):831-41. PubMed ID: 11053674
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The hypothalamus as the primary brain region of metabolic abnormalities in APP/PS1 transgenic mouse model of Alzheimer's disease.
    Zheng H; Zhou Q; Du Y; Li C; Xu P; Lin L; Xiao J; Gao H
    Biochim Biophys Acta Mol Basis Dis; 2018 Jan; 1864(1):263-273. PubMed ID: 29107091
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Telomere length and micronuclei trajectories in APP/PS1 mouse model of Alzheimer's disease: Correlating with cognitive impairment and brain amyloidosis in a sexually dimorphic manner.
    Guo X; Li J; Qi Y; Chen J; Jiang M; Zhu L; Liu Z; Wang H; Wang G; Wang X
    Aging Cell; 2024 May; 23(5):e14121. PubMed ID: 38450924
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Hyperphosphorylated tau and paired helical filament-like structures in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
    Kurt MA; Davies DC; Kidd M; Duff K; Howlett DR
    Neurobiol Dis; 2003 Oct; 14(1):89-97. PubMed ID: 13678670
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T; Kiliaan AJ; Kadish I
    Neurobiol Dis; 2006 Sep; 23(3):653-62. PubMed ID: 16829076
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Age Moderates the Effects of Traumatic Brain Injury on Beta-Amyloid Plaque Load in APP/PS1 Mice.
    Collins JM; King AE; Woodhouse A; Kirkcaldie MTK; Vickers JC
    J Neurotrauma; 2019 Jun; 36(11):1876-1889. PubMed ID: 30623730
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice.
    Liu HL; Zhao G; Zhang H; Shi LD
    Behav Brain Res; 2013 Nov; 256():261-72. PubMed ID: 23968591
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer's disease.
    Zou C; Montagna E; Shi Y; Peters F; Blazquez-Llorca L; Shi S; Filser S; Dorostkar MM; Herms J
    Acta Neuropathol; 2015 Jun; 129(6):909-20. PubMed ID: 25862638
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
    Mahan TE; Wang C; Bao X; Choudhury A; Ulrich JD; Holtzman DM
    Mol Neurodegener; 2022 Feb; 17(1):13. PubMed ID: 35109920
    [TBL] [Abstract][Full Text] [Related]  

  • 33. CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease.
    Naert G; Rivest S
    J Neurosci; 2011 Apr; 31(16):6208-20. PubMed ID: 21508244
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer's mice.
    Sawmiller D; Koyama N; Fujiwara M; Segawa T; Maeda M; Mori T
    J Biol Chem; 2023 Jul; 299(7):104846. PubMed ID: 37211092
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease.
    Willuweit A; Velden J; Godemann R; Manook A; Jetzek F; Tintrup H; Kauselmann G; Zevnik B; Henriksen G; Drzezga A; Pohlner J; Schoor M; Kemp JA; von der Kammer H
    PLoS One; 2009 Nov; 4(11):e7931. PubMed ID: 19936202
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.
    Readhead B; Haure-Mirande JV; Zhang B; Haroutunian V; Gandy S; Schadt EE; Dudley JT; Ehrlich ME
    Mol Psychiatry; 2016 Aug; 21(8):1099-111. PubMed ID: 26552589
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Multifocal Cerebral Microinfarcts Modulate Early Alzheimer's Disease Pathology in a Sex-Dependent Manner.
    Lecordier S; Pons V; Rivest S; ElAli A
    Front Immunol; 2021; 12():813536. PubMed ID: 35173711
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The role of microglial cells and astrocytes in fibrillar plaque evolution in transgenic APP(SW) mice.
    Wegiel J; Wang KC; Imaki H; Rubenstein R; Wronska A; Osuchowski M; Lipinski WJ; Walker LC; LeVine H
    Neurobiol Aging; 2001; 22(1):49-61. PubMed ID: 11164276
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Sex Differences in Neuropathology and Cognitive Behavior in APP/PS1/tau Triple-Transgenic Mouse Model of Alzheimer's Disease.
    Yang JT; Wang ZJ; Cai HY; Yuan L; Hu MM; Wu MN; Qi JS
    Neurosci Bull; 2018 Oct; 34(5):736-746. PubMed ID: 30099679
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease.
    Horibe S; Emoto T; Mizoguchi T; Tanaka T; Kawauchi S; Sasaki N; Yamashita T; Ikeda K; Emoto N; Hirata KI; Rikitake Y
    Glia; 2024 Jan; 72(1):51-68. PubMed ID: 37610154
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 29.