133 related articles for article (PubMed ID: 22952146)
1. 'The chicken or the egg?' dilemma strikes back for the controlling mechanism in chordoma(#).
Szuhai K; Hogendoorn PC
J Pathol; 2012 Nov; 228(3):261-5. PubMed ID: 22952146
[TBL] [Abstract][Full Text] [Related]
2. An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma.
Nelson AC; Pillay N; Henderson S; Presneau N; Tirabosco R; Halai D; Berisha F; Flicek P; Stemple DL; Stern CD; Wardle FC; Flanagan AM
J Pathol; 2012 Nov; 228(3):274-85. PubMed ID: 22847733
[TBL] [Abstract][Full Text] [Related]
3. Brachyury and chordoma: the chondroid-chordoid dilemma resolved?
Romeo S; Hogendoorn PC
J Pathol; 2006 Jun; 209(2):143-6. PubMed ID: 16604512
[TBL] [Abstract][Full Text] [Related]
4. The driver landscape of sporadic chordoma.
Tarpey PS; Behjati S; Young MD; Martincorena I; Alexandrov LB; Farndon SJ; Guzzo C; Hardy C; Latimer C; Butler AP; Teague JW; Shlien A; Futreal PA; Shah S; Bashashati A; Jamshidi F; Nielsen TO; Huntsman D; Baumhoer D; Brandner S; Wunder J; Dickson B; Cogswell P; Sommer J; Phillips JJ; Amary MF; Tirabosco R; Pillay N; Yip S; Stratton MR; Flanagan AM; Campbell PJ
Nat Commun; 2017 Oct; 8(1):890. PubMed ID: 29026114
[TBL] [Abstract][Full Text] [Related]
5. Novel therapeutic targets in chordoma.
Bydon M; Papadimitriou K; Witham T; Wolinsky JP; Bydon A; Sciubba D; Gokaslan Z
Expert Opin Ther Targets; 2012 Nov; 16(11):1139-43. PubMed ID: 22860993
[TBL] [Abstract][Full Text] [Related]
6. Notochordal Tumors: An Update on Molecular Pathology with Therapeutic Implications.
Yamaguchi T; Imada H; Iida S; Szuhai K
Surg Pathol Clin; 2017 Sep; 10(3):637-656. PubMed ID: 28797506
[TBL] [Abstract][Full Text] [Related]
7. A common single-nucleotide variant in T is strongly associated with chordoma.
Pillay N; Plagnol V; Tarpey PS; Lobo SB; Presneau N; Szuhai K; Halai D; Berisha F; Cannon SR; Mead S; Kasperaviciute D; Palmen J; Talmud PJ; Kindblom LG; Amary MF; Tirabosco R; Flanagan AM
Nat Genet; 2012 Nov; 44(11):1185-7. PubMed ID: 23064415
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death.
Cottone L; Cribbs AP; Khandelwal G; Wells G; Ligammari L; Philpott M; Tumber A; Lombard P; Hookway ES; Szommer T; Johansson C; Brennan PE; Pillay N; Jenner RG; Oppermann U; Flanagan AM
Cancer Res; 2020 Oct; 80(20):4540-4551. PubMed ID: 32855205
[TBL] [Abstract][Full Text] [Related]
9. Brachyury gene copy number gain and activation of the PI3K/Akt pathway: association with upregulation of oncogenic Brachyury expression in skull base chordoma.
Otani R; Mukasa A; Shin M; Omata M; Takayanagi S; Tanaka S; Ueki K; Saito N
J Neurosurg; 2018 May; 128(5):1428-1437. PubMed ID: 28753115
[TBL] [Abstract][Full Text] [Related]
10. Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity.
Sheppard HE; Dall'Agnese A; Park WD; Shamim MH; Dubrulle J; Johnson HL; Stossi F; Cogswell P; Sommer J; Levy J; Sharifnia T; Wawer MJ; Nabet B; Gray NS; Clemons PA; Schreiber SL; Workman P; Young RA; Lin CY
Cell Rep Med; 2021 Jan; 2(1):100188. PubMed ID: 33521702
[TBL] [Abstract][Full Text] [Related]
11. T (brachyury) gene duplication confers major susceptibility to familial chordoma.
Yang XR; Ng D; Alcorta DA; Liebsch NJ; Sheridan E; Li S; Goldstein AM; Parry DM; Kelley MJ
Nat Genet; 2009 Nov; 41(11):1176-8. PubMed ID: 19801981
[TBL] [Abstract][Full Text] [Related]
12. From notochord formation to hereditary chordoma: the many roles of Brachyury.
Nibu Y; José-Edwards DS; Di Gregorio A
Biomed Res Int; 2013; 2013():826435. PubMed ID: 23662285
[TBL] [Abstract][Full Text] [Related]
13. Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target.
Hsu W; Mohyeldin A; Shah SR; ap Rhys CM; Johnson LF; Sedora-Roman NI; Kosztowski TA; Awad OA; McCarthy EF; Loeb DM; Wolinsky JP; Gokaslan ZL; Quiñones-Hinojosa A
J Neurosurg; 2011 Oct; 115(4):760-9. PubMed ID: 21699479
[TBL] [Abstract][Full Text] [Related]
14. Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury.
Magnaghi P; Salom B; Cozzi L; Amboldi N; Ballinari D; Tamborini E; Gasparri F; Montagnoli A; Raddrizzani L; Somaschini A; Bosotti R; Orrenius C; Bozzi F; Pilotti S; Galvani A; Sommer J; Stacchiotti S; Isacchi A
Mol Cancer Ther; 2018 Mar; 17(3):603-613. PubMed ID: 29237806
[TBL] [Abstract][Full Text] [Related]
15. Diagnosing an extra-axial chordoma of the proximal tibia with the help of brachyury, a molecule required for notochordal differentiation.
O'donnell P; Tirabosco R; Vujovic S; Bartlett W; Briggs TW; Henderson S; Boshoff C; Flanagan AM
Skeletal Radiol; 2007 Jan; 36(1):59-65. PubMed ID: 16810540
[TBL] [Abstract][Full Text] [Related]
16. The brachyury Gly177Asp SNP is not associated with a risk of skull base chordoma in the Chinese population.
Wu Z; Wang K; Wang L; Feng J; Hao S; Tian K; Zhang L; Jia G; Wan H; Zhang J
Int J Mol Sci; 2013 Oct; 14(11):21258-65. PubMed ID: 24232574
[TBL] [Abstract][Full Text] [Related]
17. T gene isoform expression pattern is significantly different between chordomas and notochords.
Wang K; Hu Q; Wang L; Chen W; Tian K; Cao C; Wu Z; Jia G; Zhang L; Zeng C; Zhang J
Biochem Biophys Res Commun; 2015 Nov; 467(2):261-7. PubMed ID: 26435504
[TBL] [Abstract][Full Text] [Related]
18. Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas.
Vujovic S; Henderson S; Presneau N; Odell E; Jacques TS; Tirabosco R; Boshoff C; Flanagan AM
J Pathol; 2006 Jun; 209(2):157-65. PubMed ID: 16538613
[TBL] [Abstract][Full Text] [Related]
19. Poorly differentiated extra-axial extraskeletal chordoma diagnosed by methylation profiling: case report and analysis of brachyury expression in SWI/SNF-deficient tumors.
Klubíčková N; Michal M; Kinkor Z; Soukup J; Ryška A; Brtková J; Lutonský M; Hájková V; Ptáková N; Michal M; Farkas M; Švajdler M
Virchows Arch; 2024 Apr; 484(4):621-627. PubMed ID: 37594643
[TBL] [Abstract][Full Text] [Related]
20. Molecular profiling of chordoma.
Scheil-Bertram S; Kappler R; von Baer A; Hartwig E; Sarkar M; Serra M; Brüderlein S; Westhoff B; Melzner I; Bassaly B; Herms J; Hugo HH; Schulte M; Möller P
Int J Oncol; 2014 Apr; 44(4):1041-55. PubMed ID: 24452533
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
