BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 22957647)

  • 1. Retinoblastoma gene-independent G1 phase arrest by flavone, phosphatidylinositol 3-kinase inhibitor, and histone deacetylase inhibitor.
    Tomosugi M; Sowa Y; Yasuda S; Tanaka R; te Riele H; Ikawa H; Koyama M; Sakai T
    Cancer Sci; 2012 Dec; 103(12):2139-43. PubMed ID: 22957647
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct roles for p107 and p130 in Rb-independent cellular senescence.
    Lehmann BD; Brooks AM; Paine MS; Chappell WH; McCubrey JA; Terrian DM
    Cell Cycle; 2008 May; 7(9):1262-8. PubMed ID: 18418057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RB, p130 and p107 differentially repress G1/S and G2/M genes after p53 activation.
    Schade AE; Fischer M; DeCaprio JA
    Nucleic Acids Res; 2019 Dec; 47(21):11197-11208. PubMed ID: 31667499
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cells.
    Bazarov AV; Lee WJ; Bazarov I; Bosire M; Hines WC; Stankovich B; Chicas A; Lowe SW; Yaswen P
    Cell Cycle; 2012 Mar; 11(5):1008-13. PubMed ID: 22333593
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human cytomegalovirus-encoded viral cyclin-dependent kinase (v-CDK) UL97 phosphorylates and inactivates the retinoblastoma protein-related p107 and p130 proteins.
    Iwahori S; Umaña AC; VanDeusen HR; Kalejta RF
    J Biol Chem; 2017 Apr; 292(16):6583-6599. PubMed ID: 28289097
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein's C-Terminal Helix.
    Topacio BR; Zatulovskiy E; Cristea S; Xie S; Tambo CS; Rubin SM; Sage J; Kõivomägi M; Skotheim JM
    Mol Cell; 2019 May; 74(4):758-770.e4. PubMed ID: 30982746
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The cancer preventive flavonoid silibinin causes hypophosphorylation of Rb/p107 and Rb2/p130 via modulation of cell cycle regulators in human prostate carcinoma DU145 cells.
    Tyagi A; Agarwal C; Agarwal R
    Cell Cycle; 2002; 1(2):137-42. PubMed ID: 12429923
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RB and RB2/p130 genes demonstrate both specific and overlapping functions during the early steps of in vitro neural differentiation of marrow stromal stem cells.
    Jori FP; Melone MA; Napolitano MA; Cipollaro M; Cascino A; Giordano A; Galderisi U
    Cell Death Differ; 2005 Jan; 12(1):65-77. PubMed ID: 15459751
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retinoblastoma family proteins have distinct functions in pulmonary epithelial cells in vivo critical for suppressing cell growth and tumorigenesis.
    Simpson DS; Mason-Richie NA; Gettler CA; Wikenheiser-Brokamp KA
    Cancer Res; 2009 Nov; 69(22):8733-41. PubMed ID: 19887614
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.
    Sangwan M; McCurdy SR; Livne-Bar I; Ahmad M; Wrana JL; Chen D; Bremner R
    Oncogene; 2012 Nov; 31(48):5019-28. PubMed ID: 22286767
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retinoblastoma/p107/p130 pocket proteins: protein dynamics and interactions with target gene promoters.
    Stengel KR; Thangavel C; Solomon DA; Angus SP; Zheng Y; Knudsen ES
    J Biol Chem; 2009 Jul; 284(29):19265-71. PubMed ID: 19279001
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation.
    Uxa S; Bernhart SH; Mages CFS; Fischer M; Kohler R; Hoffmann S; Stadler PF; Engeland K; Müller GA
    Nucleic Acids Res; 2019 Sep; 47(17):9087-9103. PubMed ID: 31400114
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development.
    Leezer JL; Hackmiller RC; Greene RM; Pisano MM
    Orthod Craniofac Res; 2003 Feb; 6(1):32-47. PubMed ID: 12627794
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of the retinoblastoma-E2F pathway by the ubiquitin-proteasome system.
    Sengupta S; Henry RW
    Biochim Biophys Acta; 2015 Oct; 1849(10):1289-97. PubMed ID: 26319102
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell cycle blockade and differentiation of ovarian cancer cells by the histone deacetylase inhibitor trichostatin A are associated with changes in p21, Rb, and Id proteins.
    Strait KA; Dabbas B; Hammond EH; Warnick CT; Iistrup SJ; Ford CD
    Mol Cancer Ther; 2002 Nov; 1(13):1181-90. PubMed ID: 12479699
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest.
    Laplantine E; Rossi F; Sahni M; Basilico C; Cobrinik D
    J Cell Biol; 2002 Aug; 158(4):741-50. PubMed ID: 12177046
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.
    Zhang HS; Gavin M; Dahiya A; Postigo AA; Ma D; Luo RX; Harbour JW; Dean DC
    Cell; 2000 Mar; 101(1):79-89. PubMed ID: 10778858
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells.
    Jackson JG; Pereira-Smith OM
    Mol Cell Biol; 2006 Apr; 26(7):2501-10. PubMed ID: 16537896
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes.
    Wharton W; Savell J; Cress WD; Seto E; Pledger WJ
    J Biol Chem; 2000 Oct; 275(43):33981-7. PubMed ID: 10945992
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.