178 related articles for article (PubMed ID: 22959245)
1. A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs).
Banister SD; Manoli M; Doddareddy MR; Hibbs DE; Kassiou M
Bioorg Med Chem Lett; 2012 Oct; 22(19):6053-8. PubMed ID: 22959245
[TBL] [Abstract][Full Text] [Related]
2. N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects.
Banister SD; Manoli M; Barron ML; Werry EL; Kassiou M
Bioorg Med Chem; 2013 Oct; 21(19):6038-52. PubMed ID: 23981939
[TBL] [Abstract][Full Text] [Related]
3. Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivity.
Banister SD; Moussa IA; Jorgensen WT; Chua SW; Kassiou M
Bioorg Med Chem Lett; 2011 Jun; 21(12):3622-6. PubMed ID: 21555222
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and receptor affinity of novel conformationally restricted σ ligands based on the [4.3.3]propellane scaffold.
Torres-Gómez H; Lehmkuhl K; Schepmann D; Wünsch B
Eur J Med Chem; 2013; 70():78-87. PubMed ID: 24140950
[TBL] [Abstract][Full Text] [Related]
5. Trishomocubane as a scaffold for the development of selective dopamine transporter (DAT) ligands.
Banister SD; Moussa IA; Beinat C; Reynolds AJ; Schiavini P; Jorgensen WT; Kassiou M
Bioorg Med Chem Lett; 2011 Jan; 21(1):38-41. PubMed ID: 21146989
[TBL] [Abstract][Full Text] [Related]
6. Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine σ₁ receptor ligands.
Moussa IA; Banister SD; Akladios FN; Chua SW; Kassiou M
Bioorg Med Chem Lett; 2011 Oct; 21(19):5707-10. PubMed ID: 21871797
[TBL] [Abstract][Full Text] [Related]
7. Influence of trishomocubanes on sigma receptor binding of N-(1-benzyl-piperidin-4-yl)-4-[123I]iodobenzamide in vivo in the rat brain.
Liu X; Mattner F; Katsifis A; Christie M; Kassiou M
Med Chem; 2005 Jan; 1(1):31-8. PubMed ID: 16789883
[TBL] [Abstract][Full Text] [Related]
8. Trishomocubanes: novel sigma ligands modulate cocaine-induced behavioural effects.
Liu X; Banister SD; Christie MJ; Banati R; Meikle S; Coster MJ; Kassiou M
Eur J Pharmacol; 2007 Jan; 555(1):37-42. PubMed ID: 17113074
[TBL] [Abstract][Full Text] [Related]
9. Trishomocubanes: novel sigma-receptor ligands modulate amphetamine-stimulated [3H]dopamine release.
Liu X; Nuwayhid S; Christie MJ; Kassiou M; Werling LL
Eur J Pharmacol; 2001 Jun; 422(1-3):39-45. PubMed ID: 11430911
[TBL] [Abstract][Full Text] [Related]
10. 7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligands.
Banister SD; Rendina LM; Kassiou M
Bioorg Med Chem Lett; 2012 Jun; 22(12):4059-63. PubMed ID: 22607684
[TBL] [Abstract][Full Text] [Related]
11. N-Arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (σ) receptor ligands.
Banister SD; Yoo DT; Chua SW; Cui J; Mach RH; Kassiou M
Bioorg Med Chem Lett; 2011 Sep; 21(18):5289-92. PubMed ID: 21788137
[TBL] [Abstract][Full Text] [Related]
12. Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling.
Banister SD; Moussa IA; Jordan MJ; Coster MJ; Kassiou M
Bioorg Med Chem Lett; 2010 Jan; 20(1):145-8. PubMed ID: 19954972
[TBL] [Abstract][Full Text] [Related]
13. Development of Tetrahydroindazole-Based Potent and Selective Sigma-2 Receptor Ligands.
Iyamu ID; Lv W; Malik N; Mishra RK; Schiltz GE
ChemMedChem; 2019 Jul; 14(13):1248-1256. PubMed ID: 31071238
[TBL] [Abstract][Full Text] [Related]
14. Exploration of ring size in a series of cyclic vicinal diamines with σ₁ receptor affinity.
Moussa IA; Banister SD; Manoli M; Doddareddy MR; Cui J; Mach RH; Kassiou M
Bioorg Med Chem Lett; 2012 Sep; 22(17):5493-7. PubMed ID: 22850210
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationships of N-(3-phenylpropyl)-N'-benzylpiperazines: Potent ligands for sigma1 and sigma2 receptors.
Nahas RI; Lever JR; Lever SZ
Bioorg Med Chem; 2008 Jan; 16(2):755-61. PubMed ID: 18029187
[TBL] [Abstract][Full Text] [Related]
16. Molecular modeling of sigma 1 receptor ligands: a model of binding conformational and electrostatic considerations.
Gund TM; Floyd J; Jung D
J Mol Graph Model; 2004 Jan; 22(3):221-30. PubMed ID: 14629980
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and pharmacological evaluation of spirocyclic σ(1) receptor ligands with exocyclic amino moiety (increased distance 1).
Rack E; Fröhlich R; Schepmann D; Wünsch B
Bioorg Med Chem; 2011 May; 19(10):3141-51. PubMed ID: 21531141
[TBL] [Abstract][Full Text] [Related]
18. Conformational analysis, pharmacophore identification, and comparative molecular field analysis of ligands for the neuromodulatory sigma 3 receptor.
Myers AM; Charifson PS; Owens CE; Kula NS; McPhail AT; Baldessarini RJ; Booth RG; Wyrick SD
J Med Chem; 1994 Nov; 37(24):4109-17. PubMed ID: 7990111
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for sigma(1) receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives.
Zampieri D; Mamolo MG; Laurini E; Florio C; Zanette C; Fermeglia M; Posocco P; Paneni MS; Pricl S; Vio L
J Med Chem; 2009 Sep; 52(17):5380-93. PubMed ID: 19673530
[TBL] [Abstract][Full Text] [Related]
20. Structure-activity comparison of YZ-069, a novel sigma ligand, and four analogs in receptor binding and behavioral studies.
Matsumoto RR; Potelleret FH; Mack A; Pouw B; Zhang Y; Bowen WD
Pharmacol Biochem Behav; 2004 Apr; 77(4):775-81. PubMed ID: 15099923
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
