163 related articles for article (PubMed ID: 22970849)
1. Modification of residue 42 of the active site loop with a lysine-mimetic side chain rescues isochorismate-pyruvate lyase activity in Pseudomonas aeruginosa PchB.
Olucha J; Meneely KM; Lamb AL
Biochemistry; 2012 Sep; 51(38):7525-32. PubMed ID: 22970849
[TBL] [Abstract][Full Text] [Related]
2. Structure-function analyses of isochorismate-pyruvate lyase from Pseudomonas aeruginosa suggest differing catalytic mechanisms for the two pericyclic reactions of this bifunctional enzyme.
Luo Q; Olucha J; Lamb AL
Biochemistry; 2009 Jun; 48(23):5239-45. PubMed ID: 19432488
[TBL] [Abstract][Full Text] [Related]
3. Exploration of swapping enzymatic function between two proteins: a simulation study of chorismate mutase and isochorismate pyruvate lyase.
Choutko A; Eichenberger AP; van Gunsteren WF; Dolenc J
Protein Sci; 2013 Jun; 22(6):809-22. PubMed ID: 23595942
[TBL] [Abstract][Full Text] [Related]
4. pH Dependence of catalysis by Pseudomonas aeruginosa isochorismate-pyruvate lyase: implications for transition state stabilization and the role of lysine 42.
Olucha J; Ouellette AN; Luo Q; Lamb AL
Biochemistry; 2011 Aug; 50(33):7198-207. PubMed ID: 21751784
[TBL] [Abstract][Full Text] [Related]
5. Entropic and enthalpic components of catalysis in the mutase and lyase activities of Pseudomonas aeruginosa PchB.
Luo Q; Meneely KM; Lamb AL
J Am Chem Soc; 2011 May; 133(18):7229-33. PubMed ID: 21504201
[TBL] [Abstract][Full Text] [Related]
6. Salicylate biosynthesis in Pseudomonas aeruginosa. Purification and characterization of PchB, a novel bifunctional enzyme displaying isochorismate pyruvate-lyase and chorismate mutase activities.
Gaille C; Kast P; Haas D
J Biol Chem; 2002 Jun; 277(24):21768-75. PubMed ID: 11937513
[TBL] [Abstract][Full Text] [Related]
7. Mechanistic insights into the isochorismate pyruvate lyase activity of the catalytically promiscuous PchB from combinatorial mutagenesis and selection.
Künzler DE; Sasso S; Gamper M; Hilvert D; Kast P
J Biol Chem; 2005 Sep; 280(38):32827-34. PubMed ID: 16036918
[TBL] [Abstract][Full Text] [Related]
8. Lysine221 is the general base residue of the isochorismate synthase from Pseudomonas aeruginosa (PchA) in a reaction that is diffusion limited.
Meneely KM; Luo Q; Dhar P; Lamb AL
Arch Biochem Biophys; 2013 Oct; 538(1):49-56. PubMed ID: 23942051
[TBL] [Abstract][Full Text] [Related]
9. Predicting an improvement of secondary catalytic activity of promiscuous isochorismate pyruvate lyase by computational design.
Martí S; Andrés J; Moliner V; Silla E; Tuñón I; Bertran J
J Am Chem Soc; 2008 Mar; 130(10):2894-5. PubMed ID: 18281989
[No Abstract] [Full Text] [Related]
10. Structural genes for salicylate biosynthesis from chorismate in Pseudomonas aeruginosa.
Serino L; Reimmann C; Baur H; Beyeler M; Visca P; Haas D
Mol Gen Genet; 1995 Nov; 249(2):217-28. PubMed ID: 7500944
[TBL] [Abstract][Full Text] [Related]
11. NMR determination of lysine pKa values in the Pol lambda lyase domain: mechanistic implications.
Gao G; DeRose EF; Kirby TW; London RE
Biochemistry; 2006 Feb; 45(6):1785-94. PubMed ID: 16460025
[TBL] [Abstract][Full Text] [Related]
12. Exploration of structure-function relationships in Escherichia coli cystathionine γ-synthase and cystathionine β-lyase via chimeric constructs and site-specific substitutions.
Manders AL; Jaworski AF; Ahmed M; Aitken SM
Biochim Biophys Acta; 2013 Jun; 1834(6):1044-53. PubMed ID: 23470500
[TBL] [Abstract][Full Text] [Related]
13. Two crystal structures of the isochorismate pyruvate lyase from Pseudomonas aeruginosa.
Zaitseva J; Lu J; Olechoski KL; Lamb AL
J Biol Chem; 2006 Nov; 281(44):33441-9. PubMed ID: 16914555
[TBL] [Abstract][Full Text] [Related]
14. Mechanism and plasticity of isochorismate pyruvate lyase: a computational study.
Martí S; Andrés J; Moliner V; Silla E; Tuñón I; Bertrán J
J Am Chem Soc; 2009 Nov; 131(44):16156-61. PubMed ID: 19835359
[TBL] [Abstract][Full Text] [Related]
15. Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis.
Zwahlen J; Kolappan S; Zhou R; Kisker C; Tonge PJ
Biochemistry; 2007 Jan; 46(4):954-64. PubMed ID: 17240979
[TBL] [Abstract][Full Text] [Related]
16. Physical nature of intermolecular interactions within cAMP-dependent protein kinase active site: differential transition state stabilization in phosphoryl transfer reaction.
Szarek P; Dyguda-Kazimierowicz E; Tachibana A; Sokalski WA
J Phys Chem B; 2008 Sep; 112(37):11819-26. PubMed ID: 18720966
[TBL] [Abstract][Full Text] [Related]
17. Enzyme Architecture: Breaking Down the Catalytic Cage that Activates Orotidine 5'-Monophosphate Decarboxylase for Catalysis.
Reyes AC; Plache DC; Koudelka AP; Amyes TL; Gerlt JA; Richard JP
J Am Chem Soc; 2018 Dec; 140(50):17580-17590. PubMed ID: 30475611
[TBL] [Abstract][Full Text] [Related]
18. Mechanism of adenylate kinase. The "essential lysine" helps to orient the phosphates and the active site residues to proper conformations.
Byeon L; Shi Z; Tsai MD
Biochemistry; 1995 Mar; 34(10):3172-82. PubMed ID: 7880812
[TBL] [Abstract][Full Text] [Related]
19. Molecular modeling of the mechanochemical triggering mechanism for catalysis of carbon-cobalt bond homolysis in coenzyme B12.
Brown KL; Marques HM
J Inorg Biochem; 2001 Jan; 83(2-3):121-32. PubMed ID: 11237251
[TBL] [Abstract][Full Text] [Related]
20. Active-site dynamics of SpvC virulence factor from Salmonella typhimurium and density functional theory study of phosphothreonine lyase catalysis.
Smith GK; Ke Z; Hengge AC; Xu D; Xie D; Guo H
J Phys Chem B; 2009 Nov; 113(46):15327-33. PubMed ID: 19715325
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
