These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 22974281)

  • 1. Crystal structure of a preacylation complex of the β-lactamase inhibitor sulbactam bound to a sulfenamide bond-containing thiol-β-lactamase.
    Rodkey EA; Drawz SM; Sampson JM; Bethel CR; Bonomo RA; van den Akker F
    J Am Chem Soc; 2012 Oct; 134(40):16798-804. PubMed ID: 22974281
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of KPC-2 β-lactamase in complex with 3-nitrophenyl boronic acid and the penam sulfone PSR-3-226.
    Ke W; Bethel CR; Papp-Wallace KM; Pagadala SR; Nottingham M; Fernandez D; Buynak JD; Bonomo RA; van den Akker F
    Antimicrob Agents Chemother; 2012 May; 56(5):2713-8. PubMed ID: 22330909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New Conformations of Acylation Adducts of Inhibitors of β-Lactamase from Mycobacterium tuberculosis.
    Tassoni R; Blok A; Pannu NS; Ubbink M
    Biochemistry; 2019 Feb; 58(7):997-1009. PubMed ID: 30632739
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study.
    Krishnan NP; Nguyen NQ; Papp-Wallace KM; Bonomo RA; van den Akker F
    PLoS One; 2015; 10(9):e0136813. PubMed ID: 26340563
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.
    Totir MA; Padayatti PS; Helfand MS; Carey MP; Bonomo RA; Carey PR; van den Akker F
    Biochemistry; 2006 Oct; 45(39):11895-904. PubMed ID: 17002290
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal Structures of KPC-2 and SHV-1 β-Lactamases in Complex with the Boronic Acid Transition State Analog S02030.
    Nguyen NQ; Krishnan NP; Rojas LJ; Prati F; Caselli E; Romagnoli C; Bonomo RA; van den Akker F
    Antimicrob Agents Chemother; 2016 Jan; 60(3):1760-6. PubMed ID: 26729491
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase.
    Padayatti PS; Helfand MS; Totir MA; Carey MP; Carey PR; Bonomo RA; van den Akker F
    J Biol Chem; 2005 Oct; 280(41):34900-7. PubMed ID: 16055923
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244.
    Thomson JM; Distler AM; Bonomo RA
    Biochemistry; 2007 Oct; 46(40):11361-8. PubMed ID: 17848099
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Understanding the molecular determinants of substrate and inhibitor specificities in the Carbapenemase KPC-2: exploring the roles of Arg220 and Glu276.
    Papp-Wallace KM; Taracila MA; Smith KM; Xu Y; Bonomo RA
    Antimicrob Agents Chemother; 2012 Aug; 56(8):4428-38. PubMed ID: 22687511
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The G132S Mutation Enhances the Resistance of
    van Alen I; Chikunova A; Safeer AA; Ahmad MUD; Perrakis A; Ubbink M
    Biochemistry; 2021 Jul; 60(28):2236-2245. PubMed ID: 34250791
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of a novel class A β-lactamase OKP-B-6 of Klebsiella quasipneumoniae: structural characterisation and interaction with commercially available drugs.
    Bellini R; Guedes IA; Ciapina LP; de Vasconcelos ATR; Dardenne LE; Nicolás MF
    Mem Inst Oswaldo Cruz; 2022; 117():e220102. PubMed ID: 36169569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel insights into the mode of inhibition of class A SHV-1 beta-lactamases revealed by boronic acid transition state inhibitors.
    Ke W; Sampson JM; Ori C; Prati F; Drawz SM; Bethel CR; Bonomo RA; van den Akker F
    Antimicrob Agents Chemother; 2011 Jan; 55(1):174-83. PubMed ID: 21041505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone.
    Papp-Wallace KM; Bethel CR; Gootz TD; Shang W; Stroh J; Lau W; McLeod D; Price L; Marfat A; Distler A; Drawz SM; Chen H; Harry E; Nottingham M; Carey PR; Buynak JD; Bonomo RA
    Biochem Pharmacol; 2012 Feb; 83(4):462-71. PubMed ID: 22155308
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamase.
    Totir MA; Helfand MS; Carey MP; Sheri A; Buynak JD; Bonomo RA; Carey PR
    Biochemistry; 2007 Aug; 46(31):8980-7. PubMed ID: 17630699
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting Multidrug-Resistant
    Barnes MD; Kumar V; Bethel CR; Moussa SH; O'Donnell J; Rutter JD; Good CE; Hujer KM; Hujer AM; Marshall SH; Kreiswirth BN; Richter SS; Rather PN; Jacobs MR; Papp-Wallace KM; van den Akker F; Bonomo RA
    mBio; 2019 Mar; 10(2):. PubMed ID: 30862744
    [TBL] [Abstract][Full Text] [Related]  

  • 16.
    Barnes MD; Winkler ML; Taracila MA; Page MG; Desarbre E; Kreiswirth BN; Shields RK; Nguyen MH; Clancy C; Spellberg B; Papp-Wallace KM; Bonomo RA
    mBio; 2017 Oct; 8(5):. PubMed ID: 29089425
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase.
    Papp-Wallace KM; Bethel CR; Distler AM; Kasuboski C; Taracila M; Bonomo RA
    Antimicrob Agents Chemother; 2010 Feb; 54(2):890-7. PubMed ID: 20008772
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S
    Cheng Q; Xu C; Chai J; Zhang R; Wai Chi Chan E; Chen S
    ACS Infect Dis; 2020 Apr; 6(4):577-587. PubMed ID: 31709791
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Different intermediate populations formed by tazobactam, sulbactam, and clavulanate reacting with SHV-1 beta-lactamases: Raman crystallographic evidence.
    Kalp M; Totir MA; Buynak JD; Carey PR
    J Am Chem Soc; 2009 Feb; 131(6):2338-47. PubMed ID: 19161282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.
    Helfand MS; Taracila MA; Totir MA; Bonomo RA; Buynak JD; van den Akker F; Carey PR
    Biochemistry; 2007 Jul; 46(29):8689-99. PubMed ID: 17595114
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.