318 related articles for article (PubMed ID: 22976441)
1. DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction.
Wang Z; Inuzuka H; Zhong J; Fukushima H; Wan L; Liu P; Wei W
Oncotarget; 2012 Sep; 3(9):1026-35. PubMed ID: 22976441
[TBL] [Abstract][Full Text] [Related]
2. ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.
Cheng Q; Chen L; Li Z; Lane WS; Chen J
EMBO J; 2009 Dec; 28(24):3857-67. PubMed ID: 19816404
[TBL] [Abstract][Full Text] [Related]
3. Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.
Tang J; Agrawal T; Cheng Q; Qu L; Brewer MD; Chen J; Yang X
PLoS One; 2013; 8(2):e55813. PubMed ID: 23405218
[TBL] [Abstract][Full Text] [Related]
4. Mechanism of p53 stabilization by ATM after DNA damage.
Cheng Q; Chen J
Cell Cycle; 2010 Feb; 9(3):472-8. PubMed ID: 20081365
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.
Inuzuka H; Tseng A; Gao D; Zhai B; Zhang Q; Shaik S; Wan L; Ang XL; Mock C; Yin H; Stommel JM; Gygi S; Lahav G; Asara J; Xiao ZX; Kaelin WG; Harper JW; Wei W
Cancer Cell; 2010 Aug; 18(2):147-59. PubMed ID: 20708156
[TBL] [Abstract][Full Text] [Related]
6. Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.
Jin J; Ang XL; Ye X; Livingstone M; Harper JW
J Biol Chem; 2008 Jul; 283(28):19322-8. PubMed ID: 18480045
[TBL] [Abstract][Full Text] [Related]
7. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
[TBL] [Abstract][Full Text] [Related]
8. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.
Pereg Y; Shkedy D; de Graaf P; Meulmeester E; Edelson-Averbukh M; Salek M; Biton S; Teunisse AF; Lehmann WD; Jochemsen AG; Shiloh Y
Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5056-61. PubMed ID: 15788536
[TBL] [Abstract][Full Text] [Related]
9. ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.
Khoronenkova SV; Dianova II; Ternette N; Kessler BM; Parsons JL; Dianov GL
Mol Cell; 2012 Mar; 45(6):801-13. PubMed ID: 22361354
[TBL] [Abstract][Full Text] [Related]
10. The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro.
Winston JT; Strack P; Beer-Romero P; Chu CY; Elledge SJ; Harper JW
Genes Dev; 1999 Feb; 13(3):270-83. PubMed ID: 9990852
[TBL] [Abstract][Full Text] [Related]
11. ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.
Taira N; Yamamoto H; Yamaguchi T; Miki Y; Yoshida K
J Biol Chem; 2010 Feb; 285(7):4909-19. PubMed ID: 19965871
[TBL] [Abstract][Full Text] [Related]
12. ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.
Dornan D; Shimizu H; Mah A; Dudhela T; Eby M; O'rourke K; Seshagiri S; Dixit VM
Science; 2006 Aug; 313(5790):1122-6. PubMed ID: 16931761
[TBL] [Abstract][Full Text] [Related]
13. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
[TBL] [Abstract][Full Text] [Related]
14. ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2A.
Shouse GP; Nobumori Y; Panowicz MJ; Liu X
Oncogene; 2011 Sep; 30(35):3755-65. PubMed ID: 21460856
[TBL] [Abstract][Full Text] [Related]
15. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
[TBL] [Abstract][Full Text] [Related]
16. ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice.
Gannon HS; Woda BA; Jones SN
Cancer Cell; 2012 May; 21(5):668-679. PubMed ID: 22624716
[TBL] [Abstract][Full Text] [Related]
17. A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz M; Stilmann M; Arslan SÇ; Khanna KK; Dittmar G; Scheidereit C
Mol Cell; 2010 Oct; 40(1):63-74. PubMed ID: 20932475
[TBL] [Abstract][Full Text] [Related]
18. SCF β-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration.
Zhong J; Shaik S; Wan L; Tron AE; Wang Z; Sun L; Inuzuka H; Wei W
Oncotarget; 2013 Dec; 4(12):2339-53. PubMed ID: 24318128
[TBL] [Abstract][Full Text] [Related]
19. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
Brew CT; Aronchik I; Hsu JC; Sheen JH; Dickson RB; Bjeldanes LF; Firestone GL
Int J Cancer; 2006 Feb; 118(4):857-68. PubMed ID: 16152627
[TBL] [Abstract][Full Text] [Related]
20. The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis.
Lau AW; Fukushima H; Wei W
Front Biosci (Landmark Ed); 2012 Jun; 17(6):2197-212. PubMed ID: 22652772
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]