BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 22981863)

  • 1. LAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation.
    Rouquette-Jazdanian AK; Sommers CL; Kortum RL; Morrison DK; Samelson LE
    Mol Cell; 2012 Oct; 48(2):298-312. PubMed ID: 22981863
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LAT alleviates Th2/Treg imbalance in an OVA-induced allergic asthma mouse model through LAT-PLC-γ1 interaction.
    Chen X; Li XM; Gu W; Wang D; Chen Y; Guo XJ
    Int Immunopharmacol; 2017 Mar; 44():9-15. PubMed ID: 28063403
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT.
    Yablonski D; Kadlecek T; Weiss A
    Mol Cell Biol; 2001 Jul; 21(13):4208-18. PubMed ID: 11390650
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line.
    Irvin BJ; Williams BL; Nilson AE; Maynor HO; Abraham RT
    Mol Cell Biol; 2000 Dec; 20(24):9149-61. PubMed ID: 11094067
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activated PLC-γ1 is catalytically induced at LAT but activated PLC-γ1 is localized at both LAT- and TCR-containing complexes.
    Cruz-Orcutt N; Vacaflores A; Connolly SF; Bunnell SC; Houtman JC
    Cell Signal; 2014 Apr; 26(4):797-805. PubMed ID: 24412752
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1.
    Phee H; Abraham RT; Weiss A
    Nat Immunol; 2005 Jun; 6(6):608-17. PubMed ID: 15864311
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling.
    Zhang W; Trible RP; Zhu M; Liu SK; McGlade CJ; Samelson LE
    J Biol Chem; 2000 Jul; 275(30):23355-61. PubMed ID: 10811803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76.
    Gonen R; Beach D; Ainey C; Yablonski D
    J Biol Chem; 2005 Mar; 280(9):8364-70. PubMed ID: 15623534
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct interaction of SOS1 Ras exchange protein with the SH3 domain of phospholipase C-gamma1.
    Kim MJ; Chang JS; Park SK; Hwang JI; Ryu SH; Suh PG
    Biochemistry; 2000 Jul; 39(29):8674-82. PubMed ID: 10913276
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice.
    Miyaji M; Kortum RL; Surana R; Li W; Woolard KD; Simpson RM; Samelson LE; Sommers CL
    Proc Natl Acad Sci U S A; 2009 Aug; 106(34):14502-7. PubMed ID: 19667175
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phospholipase activity of phospholipase C-gamma1 is required for nerve growth factor-regulated MAP kinase signaling cascade in PC12 cells.
    Rong R; Ahn JY; Chen P; Suh PG; Ye K
    J Biol Chem; 2003 Dec; 278(52):52497-503. PubMed ID: 14570902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.
    Williams BL; Irvin BJ; Sutor SL; Chini CC; Yacyshyn E; Bubeck Wardenburg J; Dalton M; Chan AC; Abraham RT
    EMBO J; 1999 Apr; 18(7):1832-44. PubMed ID: 10202147
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Basic fibroblast growth factor-induced translocation of p21-activated kinase to the membrane is independent of phospholipase C-gamma1 in the differentiation of PC12 cells.
    Shin KS; Shin EY; Lee CS; Quan SH; Woo KN; Soung NK; Kwak SJ; Kim SR; Kim EG
    Exp Mol Med; 2002 May; 34(2):172-6. PubMed ID: 12085993
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells.
    Lindholm CK; Gylfe E; Zhang W; Samelson LE; Welsh M
    J Biol Chem; 1999 Sep; 274(39):28050-7. PubMed ID: 10488157
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survival.
    Niiro H; Maeda A; Kurosaki T; Clark EA
    J Exp Med; 2002 Jan; 195(1):143-9. PubMed ID: 11781373
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 70Z/3 Cbl induces PLC gamma 1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism.
    Graham LJ; Verí MC; DeBell KE; Noviello C; Rawat R; Jen S; Bonvini E; Rellahan B
    Oncogene; 2003 Apr; 22(16):2493-503. PubMed ID: 12717426
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses.
    Kremer KN; Clift IC; Miamen AG; Bamidele AO; Qian NX; Humphreys TD; Hedin KE
    J Immunol; 2011 Aug; 187(3):1440-7. PubMed ID: 21705626
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p21-activated kinase 1 (PAK1) can promote ERK activation in a kinase-independent manner.
    Wang Z; Fu M; Wang L; Liu J; Li Y; Brakebusch C; Mei Q
    J Biol Chem; 2013 Jul; 288(27):20093-9. PubMed ID: 23653349
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.
    Ku GM; Yablonski D; Manser E; Lim L; Weiss A
    EMBO J; 2001 Feb; 20(3):457-65. PubMed ID: 11157752
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The SH2-SH2-SH3 domain of phospholipase C-gamma1 directly binds to translational elongation factor-1alpha.
    Kim MJ; Si F; Kim SJ; Hong SB; Hwang JI; Lee HJ; Lee SJ; Chang JS; Lee YH; Ryu SH; Suh PG
    Mol Cells; 1999 Dec; 9(6):631-7. PubMed ID: 10672930
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.