These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

627 related articles for article (PubMed ID: 22982527)

  • 21. Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone.
    Conchon E; Anizon F; Aboab B; Golsteyn RM; Léonce S; Pfeiffer B; Prudhomme M
    Eur J Med Chem; 2008 Feb; 43(2):282-92. PubMed ID: 17502122
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity.
    Pierre F; Stefan E; Nédellec AS; Chevrel MC; Regan CF; Siddiqui-Jain A; Macalino D; Streiner N; Drygin D; Haddach M; O'Brien SE; Anderes K; Ryckman DM
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6687-92. PubMed ID: 21982499
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and biological evaluation of quinoline derivatives as potential anti-prostate cancer agents and Pim-1 kinase inhibitors.
    Li K; Li Y; Zhou D; Fan Y; Guo H; Ma T; Wen J; Liu D; Zhao L
    Bioorg Med Chem; 2016 Apr; 24(8):1889-97. PubMed ID: 26979485
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and evaluation of 5-substituted 9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as check point 1 kinase inhibitors.
    Sako Y; Ichikawa S; Osada A; Matsuda A
    Bioorg Med Chem; 2010 Nov; 18(22):7878-89. PubMed ID: 20943405
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Discovery of novel triazolo[4,3-b]pyridazin-3-yl-quinoline derivatives as PIM inhibitors.
    Martínez-González S; Rodríguez-Arístegui S; Gómez de la Oliva CA; Hernández AI; González Cantalapiedra E; Varela C; García AB; Rabal O; Oyarzabal J; Bischoff JR; Klett J; Albarrán MI; Cebriá A; Ajenjo N; García-Serelde B; Gómez-Casero E; Cuadrado-Urbano M; Cebrián D; Blanco-Aparicio C; Pastor J
    Eur J Med Chem; 2019 Apr; 168():87-109. PubMed ID: 30802730
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis and biological activities of new checkpoint kinase 1 inhibitors structurally related to granulatimide.
    Conchon E; Anizon F; Aboab B; Prudhomme M
    J Med Chem; 2007 Sep; 50(19):4669-80. PubMed ID: 17722905
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis and in vitro antitumor activity of novel 2-alkyl-5-methoxycarbonyl-11-methyl-6H-pyrido[4,3-b]carbazol-2-ium and 2-alkylellipticin-2-ium chloride derivatives.
    Mori R; Kato A; Komenoi K; Kurasaki H; Iijima T; Kawagoshi M; Kiran YB; Takeda S; Sakai N; Konakahara T
    Eur J Med Chem; 2014 Jul; 82():16-35. PubMed ID: 24863982
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors.
    Bass AKA; Nageeb EM; El-Zoghbi MS; Mohamed MFA; Badr M; Abuo-Rahma GEA
    Bioorg Chem; 2022 Feb; 119():105564. PubMed ID: 34959179
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The design, synthesis, and biological evaluation of PIM kinase inhibitors.
    Tsuhako AL; Brown DS; Koltun ES; Aay N; Arcalas A; Chan V; Du H; Engst S; Franzini M; Galan A; Huang P; Johnston S; Kane B; Kim MH; Laird AD; Lin R; Mock L; Ngan I; Pack M; Stott G; Stout TJ; Yu P; Zaharia C; Zhang W; Zhou P; Nuss JM; Kearney PC; Xu W
    Bioorg Med Chem Lett; 2012 Jun; 22(11):3732-8. PubMed ID: 22542012
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities.
    Abouzid KAM; Al-Ansary GH; El-Naggar AM
    Eur J Med Chem; 2017 Jul; 134():357-365. PubMed ID: 28431341
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors.
    Mori M; Tintori C; Christopher RS; Radi M; Schenone S; Musumeci F; Brullo C; Sanità P; Delle Monache S; Angelucci A; Kissova M; Crespan E; Maga G; Botta M
    ChemMedChem; 2013 Mar; 8(3):484-96. PubMed ID: 23436791
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases.
    Dao VH; Ourliac-Garnier I; Logé C; McCarthy FO; Bach S; da Silva TG; Denevault-Sabourin C; Thiéfaine J; Baratte B; Robert T; Gouilleux F; Brachet-Botineau M; Bazin MA; Marchand P
    Molecules; 2021 Oct; 26(21):. PubMed ID: 34770981
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles.
    Conchon E; Anizon F; Aboab B; Golsteyn RM; Léonce S; Pfeiffer B; Prudhomme M
    Bioorg Med Chem; 2008 Apr; 16(8):4419-30. PubMed ID: 18321713
    [TBL] [Abstract][Full Text] [Related]  

  • 34. New cyanopyridine-based scaffold as PIM-1 inhibitors and apoptotic inducers: Synthesis and SARs study.
    Farrag AM; Ibrahim MH; Mehany ABM; Ismail MMF
    Bioorg Chem; 2020 Dec; 105():104378. PubMed ID: 33099167
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis and antiproliferative activity of new cytotoxic azanaphthoquinone pyrrolo-annelated derivatives: Part II.
    Shanab K; Schirmer E; Wulz E; Weissenbacher B; Lassnig S; Slanz R; Fösleitner G; Holzer W; Spreitzer H; Schmidt P; Aicher B; Müller G; Günther E
    Bioorg Med Chem Lett; 2011 May; 21(10):3117-21. PubMed ID: 21458262
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis and biological evaluation of new cytotoxic azanaphthoquinone pyrrolo-annelated derivatives.
    Shanab K; Schirmer E; Knafl H; Wulz E; Holzer W; Spreitzer H; Schmidt P; Aicher B; Müller G; Günther E
    Bioorg Med Chem Lett; 2010 Jul; 20(13):3950-2. PubMed ID: 20537894
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design and synthesis of substituted pyrido[3,2-d]-1,2,3-triazines as potential Pim-1 inhibitors.
    Fan YB; Li K; Huang M; Cao Y; Li Y; Jin SY; Liu WB; Wen JC; Liu D; Zhao LX
    Bioorg Med Chem Lett; 2016 Feb; 26(4):1224-8. PubMed ID: 26804231
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2.
    Guillon J; Le Borgne M; Rimbault C; Moreau S; Savrimoutou S; Pinaud N; Baratin S; Marchivie M; Roche S; Bollacke A; Pecci A; Alvarez L; Desplat V; Jose J
    Eur J Med Chem; 2013 Jul; 65():205-22. PubMed ID: 23711832
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations.
    Mahmoud MAA; Mohareb RM; Al-Sharif MA
    Anticancer Agents Med Chem; 2018; 18(12):1711-1728. PubMed ID: 29732981
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Antiproliferative activity of some 1,4-dimethylcarbazoles on cells that express estrogen receptors: part I.
    Caruso A; Chimento A; El-Kashef H; Lancelot JC; Panno A; Pezzi V; Saturnino C; Sinicropi MS; Sirianni R; Rault S
    J Enzyme Inhib Med Chem; 2012 Aug; 27(4):609-13. PubMed ID: 21883039
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 32.