BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 22983166)

  • 1. Development of a fluorescence intensity assay for the mitotic serine/threonine protein kinase Aurora-A.
    Slatter AF; Campbell S; Angell RM
    J Biomol Screen; 2013 Feb; 18(2):219-25. PubMed ID: 22983166
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of selective aminothiazole aurora kinase inhibitors.
    Andersen CB; Wan Y; Chang JW; Riggs B; Lee C; Liu Y; Sessa F; Villa F; Kwiatkowski N; Suzuki M; Nallan L; Heald R; Musacchio A; Gray NS
    ACS Chem Biol; 2008 Mar; 3(3):180-92. PubMed ID: 18307303
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aurora kinase inhibitors.
    Kitzen JJ; de Jonge MJ; Verweij J
    Crit Rev Oncol Hematol; 2010 Feb; 73(2):99-110. PubMed ID: 19369091
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clinical experience with aurora kinase inhibitors: a review.
    Boss DS; Beijnen JH; Schellens JH
    Oncologist; 2009 Aug; 14(8):780-93. PubMed ID: 19684075
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aurora kinases: new targets for cancer therapy.
    Carvajal RD; Tse A; Schwartz GK
    Clin Cancer Res; 2006 Dec; 12(23):6869-75. PubMed ID: 17145803
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development and biological evaluation of a novel aurora A kinase inhibitor.
    Sardon T; Cottin T; Xu J; Giannis A; Vernos I
    Chembiochem; 2009 Feb; 10(3):464-78. PubMed ID: 19199284
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Is there a future for Aurora kinase inhibitors for anticancer therapy?
    Carpinelli P; Moll J
    Curr Opin Drug Discov Devel; 2009 Jul; 12(4):533-42. PubMed ID: 19562649
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of alkenyl indazoles as selective Aurora kinase inhibitors.
    Blanchard S; William AD; Lee AC; Poulsen A; Teo EL; Deng W; Tu N; Tan E; Goh KL; Ong WC; Ng CP; Goh KC; Bonday Z; Sun ET
    Bioorg Med Chem Lett; 2010 Apr; 20(8):2443-7. PubMed ID: 20338758
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
    Aliagas-Martin I; Burdick D; Corson L; Dotson J; Drummond J; Fields C; Huang OW; Hunsaker T; Kleinheinz T; Krueger E; Liang J; Moffat J; Phillips G; Pulk R; Rawson TE; Ultsch M; Walker L; Wiesmann C; Zhang B; Zhu BY; Cochran AG
    J Med Chem; 2009 May; 52(10):3300-7. PubMed ID: 19402633
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of a novel fluorescent probe for fluorescence correlation spectroscopic detection of kinase inhibitors.
    Kawaguchi M; Terai T; Utata R; Kato M; Tsuganezawa K; Tanaka A; Kojima H; Okabe T; Nagano T
    Bioorg Med Chem Lett; 2008 Jul; 18(13):3752-5. PubMed ID: 18524589
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Advances in Aurora kinase inhibitor patents.
    Coumar MS; Cheung CH; Chang JY; Hsieh HP
    Expert Opin Ther Pat; 2009 Mar; 19(3):321-56. PubMed ID: 19441907
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification, SAR studies, and X-ray co-crystallographic analysis of a novel furanopyrimidine aurora kinase A inhibitor.
    Coumar MS; Tsai MT; Chu CY; Uang BJ; Lin WH; Chang CY; Chang TY; Leou JS; Teng CH; Wu JS; Fang MY; Chen CH; Hsu JT; Wu SY; Chao YS; Hsieh HP
    ChemMedChem; 2010 Feb; 5(2):255-67. PubMed ID: 20039358
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase.
    Yang H; Burke T; Dempsey J; Diaz B; Collins E; Toth J; Beckmann R; Ye X
    FEBS Lett; 2005 Jun; 579(16):3385-91. PubMed ID: 15922328
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of potent and selective thienopyrimidine inhibitors of Aurora kinases.
    McClellan WJ; Dai Y; Abad-Zapatero C; Albert DH; Bouska JJ; Glaser KB; Magoc TJ; Marcotte PA; Osterling DJ; Stewart KD; Davidsen SK; Michaelides MR
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5620-4. PubMed ID: 21778056
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The dietary flavonoid luteolin inhibits Aurora B kinase activity and blocks proliferation of cancer cells.
    Xie F; Lang Q; Zhou M; Zhang H; Zhang Z; Zhang Y; Wan B; Huang Q; Yu L
    Eur J Pharm Sci; 2012 Aug; 46(5):388-96. PubMed ID: 22449725
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity.
    Howard S; Berdini V; Boulstridge JA; Carr MG; Cross DM; Curry J; Devine LA; Early TR; Fazal L; Gill AL; Heathcote M; Maman S; Matthews JE; McMenamin RL; Navarro EF; O'Brien MA; O'Reilly M; Rees DC; Reule M; Tisi D; Williams G; Vinković M; Wyatt PG
    J Med Chem; 2009 Jan; 52(2):379-88. PubMed ID: 19143567
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity.
    Coumar MS; Leou JS; Shukla P; Wu JS; Dixit AK; Lin WH; Chang CY; Lien TW; Tan UK; Chen CH; Hsu JT; Chao YS; Wu SY; Hsieh HP
    J Med Chem; 2009 Feb; 52(4):1050-62. PubMed ID: 19140666
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aurora kinases as anticancer drug targets.
    Gautschi O; Heighway J; Mack PC; Purnell PR; Lara PN; Gandara DR
    Clin Cancer Res; 2008 Mar; 14(6):1639-48. PubMed ID: 18347165
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aurora kinases as targets for cancer therapy.
    Mountzios G; Terpos E; Dimopoulos MA
    Cancer Treat Rev; 2008 Apr; 34(2):175-82. PubMed ID: 18023292
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aurora kinase inhibitors as anti-cancer therapy.
    Lok W; Klein RQ; Saif MW
    Anticancer Drugs; 2010 Apr; 21(4):339-50. PubMed ID: 20016367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.