These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
152 related articles for article (PubMed ID: 22984987)
1. Discovery of diverse human dihydroorotate dehydrogenase inhibitors as immunosuppressive agents by structure-based virtual screening. Diao Y; Lu W; Jin H; Zhu J; Han L; Xu M; Gao R; Shen X; Zhao Z; Liu X; Xu Y; Huang J; Li H J Med Chem; 2012 Oct; 55(19):8341-9. PubMed ID: 22984987 [TBL] [Abstract][Full Text] [Related]
2. Identification of novel PfDHODH inhibitors as antimalarial agents via pharmacophore-based virtual screening followed by molecular docking and in vivo antimalarial activity. Vyas VK; Qureshi G; Ghate M; Patel H; Dalai S SAR QSAR Environ Res; 2016 Jun; 27(6):427-40. PubMed ID: 27310104 [TBL] [Abstract][Full Text] [Related]
3. Synthesis, Design, and Structure⁻Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of Xu L; Li W; Diao Y; Sun H; Li H; Zhu L; Zhou H; Zhao Z Molecules; 2018 May; 23(6):. PubMed ID: 29794978 [TBL] [Abstract][Full Text] [Related]
4. Synthesis of brequinar analogue inhibitors of malaria parasite dihydroorotate dehydrogenase. Boa AN; Canavan SP; Hirst PR; Ramsey C; Stead AM; McConkey GA Bioorg Med Chem; 2005 Mar; 13(6):1945-67. PubMed ID: 15727850 [TBL] [Abstract][Full Text] [Related]
5. Identification of New Human Malaria Parasite Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors by Pharmacophore and Structure-Based Virtual Screening. Pavadai E; El Mazouni F; Wittlin S; de Kock C; Phillips MA; Chibale K J Chem Inf Model; 2016 Mar; 56(3):548-62. PubMed ID: 26915022 [TBL] [Abstract][Full Text] [Related]
6. Discovery of a new structural class of competitive hDHODH inhibitors with in vitro and in vivo anti-inflammatory, immunosuppressive effects. Shen W; Ren X; Zhu J; Xu Y; Lin J; Li Y; Zhao F; Zheng H; Li R; Cui X; Zhang X; Lu X; Zheng Z Eur J Pharmacol; 2016 Nov; 791():205-212. PubMed ID: 27597161 [TBL] [Abstract][Full Text] [Related]
7. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives. Xu M; Zhu J; Diao Y; Zhou H; Ren X; Sun D; Huang J; Han D; Zhao Z; Zhu L; Xu Y; Li H J Med Chem; 2013 Oct; 56(20):7911-24. PubMed ID: 24073986 [TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds. Sainas S; Pippione AC; Giorgis M; Lupino E; Goyal P; Ramondetti C; Buccinnà B; Piccinini M; Braga RC; Andrade CH; Andersson M; Moritzer AC; Friemann R; Mensa S; Al-Kadaraghi S; Boschi D; Lolli ML Eur J Med Chem; 2017 Mar; 129():287-302. PubMed ID: 28235702 [TBL] [Abstract][Full Text] [Related]
9. In silico identification of novel inhibitors against Plasmodium falciparum dihydroorate dehydrogenase. Wadood A; Ulhaq ZU J Mol Graph Model; 2013 Mar; 40():40-7. PubMed ID: 23353582 [TBL] [Abstract][Full Text] [Related]
10. Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors. Azeredo LFSP; Coutinho JP; Jabor VAP; Feliciano PR; Nonato MC; Kaiser CR; Menezes CMS; Hammes ASO; Caffarena ER; Hoelz LVB; de Souza NB; Pereira GAN; Cerávolo IP; Krettli AU; Boechat N Eur J Med Chem; 2017 Jan; 126():72-83. PubMed ID: 27744189 [TBL] [Abstract][Full Text] [Related]
11. Synthesis and evaluation of a novel series of quinoline derivatives with immunosuppressive activity. Liu GB; Xu JL; He CC; Chen G; Xu Q; Xu HX; Li JX Bioorg Med Chem; 2009 Aug; 17(15):5433-41. PubMed ID: 19596582 [TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase. Heikkilä T; Ramsey C; Davies M; Galtier C; Stead AM; Johnson AP; Fishwick CW; Boa AN; McConkey GA J Med Chem; 2007 Jan; 50(2):186-91. PubMed ID: 17228860 [TBL] [Abstract][Full Text] [Related]
14. Synthesis, biological evaluation and molecular docking studies of 1,3,4-oxadiazole derivatives as potential immunosuppressive agents. Zhang ZM; Zhang XW; Zhao ZZ; Yan R; Xu R; Gong HB; Zhu HL Bioorg Med Chem; 2012 May; 20(10):3359-67. PubMed ID: 22520630 [TBL] [Abstract][Full Text] [Related]
15. Synthesis, biological evaluation of chrysin derivatives as potential immunosuppressive agents. Lv PC; Cai TT; Qian Y; Sun J; Zhu HL Eur J Med Chem; 2011 Jan; 46(1):393-8. PubMed ID: 21131104 [TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents. Vyas VK; Variya B; Ghate MD Eur J Med Chem; 2014 Jul; 82():385-93. PubMed ID: 24929289 [TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of novel substituted benzamide derivatives bearing a 1,2,3-triazole moiety as potent human dihydroorotate dehydrogenase inhibitors. Lu K; Cai L; Zhang X; Wu G; Xu C; Zhao Y; Gong P Bioorg Chem; 2018 Feb; 76():528-537. PubMed ID: 29316525 [TBL] [Abstract][Full Text] [Related]
18. Pyrazole bioisosteres of leflunomide as B-cell immunosuppressants for xenotransplantation and chronic rejection: scope and limitations. Papageorgiou C; Albert R; Floersheim P; Lemaire M; Bitch F; Weber HP; Andersen E; Hungerford V; Schreier MH J Med Chem; 1998 Aug; 41(18):3530-8. PubMed ID: 9719606 [TBL] [Abstract][Full Text] [Related]
19. Structural Optimization and Structure-Activity Relationship of 4-Thiazolidinone Derivatives as Novel Inhibitors of Human Dihydroorotate Dehydrogenase. Zeng F; Quan L; Yang G; Qi T; Zhang L; Li S; Li H; Zhu L; Xu X Molecules; 2019 Jul; 24(15):. PubMed ID: 31370178 [TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, biological evaluation and molecular modeling of novel 1,3,4-oxadiazole derivatives based on Vanillic acid as potential immunosuppressive agents. Tang JF; Lv XH; Wang XL; Sun J; Zhang YB; Yang YS; Gong HB; Zhu HL Bioorg Med Chem; 2012 Jul; 20(14):4226-36. PubMed ID: 22727369 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]