188 related articles for article (PubMed ID: 22985361)
1. Human cystathionine β-synthase (CBS) contains two classes of binding sites for S-adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM.
Pey AL; Majtan T; Sanchez-Ruiz JM; Kraus JP
Biochem J; 2013 Jan; 449(1):109-21. PubMed ID: 22985361
[TBL] [Abstract][Full Text] [Related]
2. Kinetic stability of cystathionine beta-synthase can be modulated by structural analogs of S-adenosylmethionine: Potential approach to pharmacological chaperone therapy for homocystinuria.
Majtan T; Pey AL; Kraus JP
Biochimie; 2016 Jul; 126():6-13. PubMed ID: 26805382
[TBL] [Abstract][Full Text] [Related]
3. Insights into the regulatory domain of cystathionine Beta-synthase: characterization of six variant proteins.
Mendes MI; Santos AS; Smith DE; Lino PR; Colaço HG; de Almeida IT; Vicente JB; Salomons GS; Rivera I; Blom HJ; Leandro P
Hum Mutat; 2014 Oct; 35(10):1195-202. PubMed ID: 25044645
[TBL] [Abstract][Full Text] [Related]
4. Reduced response of Cystathionine Beta-Synthase (CBS) to S-Adenosylmethionine (SAM): Identification and functional analysis of CBS gene mutations in Homocystinuria patients.
Mendes MI; Colaço HG; Smith DE; Ramos RJ; Pop A; van Dooren SJ; Tavares de Almeida I; Kluijtmans LA; Janssen MC; Rivera I; Salomons GS; Leandro P; Blom HJ
J Inherit Metab Dis; 2014 Mar; 37(2):245-54. PubMed ID: 23974653
[TBL] [Abstract][Full Text] [Related]
5. Potential Pharmacological Chaperones for Cystathionine Beta-Synthase-Deficient Homocystinuria.
Majtan T; Pey AL; Gimenez-Mascarell P; Martínez-Cruz LA; Szabo C; Kožich V; Kraus JP
Handb Exp Pharmacol; 2018; 245():345-383. PubMed ID: 29119254
[TBL] [Abstract][Full Text] [Related]
6. Characterization of two pathogenic mutations in cystathionine beta-synthase: different intracellular locations for wild-type and mutant proteins.
Casique L; Kabil O; Banerjee R; Martinez JC; De Lucca M
Gene; 2013 Nov; 531(1):117-24. PubMed ID: 23981774
[TBL] [Abstract][Full Text] [Related]
7. Oligomeric status of human cystathionine beta-synthase modulates AdoMet binding.
Pey AL; Martínez-Cruz LA; Kraus JP; Majtan T
FEBS Lett; 2016 Dec; 590(24):4461-4471. PubMed ID: 27861796
[TBL] [Abstract][Full Text] [Related]
8. Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria.
Al-Sadeq DW; Conter C; Thanassoulas A; Al-Dewik N; Safieh-Garabedian B; Martínez-Cruz LA; Nasrallah GK; Astegno A; Nomikos M
Biochem J; 2024 Apr; 481(8):569-585. PubMed ID: 38563463
[TBL] [Abstract][Full Text] [Related]
9. The role of surface electrostatics on the stability, function and regulation of human cystathionine β-synthase, a complex multidomain and oligomeric protein.
Pey AL; Majtan T; Kraus JP
Biochim Biophys Acta; 2014 Sep; 1844(9):1453-62. PubMed ID: 24780582
[TBL] [Abstract][Full Text] [Related]
10. Mutations in the regulatory domain of cystathionine beta synthase can functionally suppress patient-derived mutations in cis.
Shan X; Dunbrack RL; Christopher SA; Kruger WD
Hum Mol Genet; 2001 Mar; 10(6):635-43. PubMed ID: 11230183
[TBL] [Abstract][Full Text] [Related]
11. The role of cystathionine beta-synthase in homocysteine metabolism.
Jhee KH; Kruger WD
Antioxid Redox Signal; 2005; 7(5-6):813-22. PubMed ID: 15890029
[TBL] [Abstract][Full Text] [Related]
12. Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation.
Roman JV; Mascarenhas R; Ceric K; Ballou DP; Banerjee R
J Biol Chem; 2023 Dec; 299(12):105449. PubMed ID: 37949228
[TBL] [Abstract][Full Text] [Related]
13. Inter-domain communication of human cystathionine β-synthase: structural basis of S-adenosyl-L-methionine activation.
McCorvie TJ; Kopec J; Hyung SJ; Fitzpatrick F; Feng X; Termine D; Strain-Damerell C; Vollmar M; Fleming J; Janz JM; Bulawa C; Yue WW
J Biol Chem; 2014 Dec; 289(52):36018-30. PubMed ID: 25336647
[TBL] [Abstract][Full Text] [Related]
14. Allosteric communication between the pyridoxal 5'-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase.
Yadav PK; Xie P; Banerjee R
J Biol Chem; 2012 Nov; 287(45):37611-20. PubMed ID: 22977242
[TBL] [Abstract][Full Text] [Related]
15. Genetic and Pharmacological Modulation of Cellular Proteostasis Leads to Partial Functional Rescue of Homocystinuria-Causing Cystathionine-Beta Synthase Variants.
Collard R; Majtan T
Mol Cell Biol; 2023; 43(12):664-674. PubMed ID: 38051092
[TBL] [Abstract][Full Text] [Related]
16. Solvent-accessible cysteines in human cystathionine beta-synthase: crucial role of cysteine 431 in S-adenosyl-L-methionine binding.
Frank N; Kery V; Maclean KN; Kraus JP
Biochemistry; 2006 Sep; 45(36):11021-9. PubMed ID: 16953589
[TBL] [Abstract][Full Text] [Related]
17. Targeting Cystathionine Beta-Synthase Misfolding in Homocystinuria by Small Ligands: State of the Art and Future Directions.
Majtan T; Pey AL; Ereño-Orbea J; Martínez-Cruz LA; Kraus JP
Curr Drug Targets; 2016; 17(13):1455-70. PubMed ID: 26931358
[TBL] [Abstract][Full Text] [Related]
18. High homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations.
Maclean KN; Gaustadnes M; Oliveriusová J; Janosík M; Kraus E; Kozich V; Kery V; Skovby F; Rüdiger N; Ingerslev J; Stabler SP; Allen RH; Kraus JP
Hum Mutat; 2002 Jun; 19(6):641-55. PubMed ID: 12007221
[TBL] [Abstract][Full Text] [Related]
19. Defective cystathionine beta-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient.
Kluijtmans LA; Boers GH; Stevens EM; Renier WO; Kraus JP; Trijbels FJ; van den Heuvel LP; Blom HJ
J Clin Invest; 1996 Jul; 98(2):285-9. PubMed ID: 8755636
[TBL] [Abstract][Full Text] [Related]
20. Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase for treatment of homocystinuria.
Majtan T; Bublil EM; Park I; Arning E; Bottiglieri T; Glavin F; Kraus JP
Life Sci; 2018 May; 200():15-25. PubMed ID: 29526799
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
