These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

73 related articles for article (PubMed ID: 22985958)

  • 21. Synthesis and Evaluation of Osteogenic Oxysterols as Hedgehog Pathway Activators.
    Maschinot CA; Corman AR; DeBerardinis AM; Hadden MK
    ChemMedChem; 2016 Apr; 11(7):679-86. PubMed ID: 26919682
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.
    Nagao S; Yamane Y; Funasaka S; Tanaka K; Miyazaki K; Kotake Y; Kamata J; Watanabe-Miyano S; Toyama O; Ozawa Y; Mizui Y; Okamoto K; Ito D
    Bioorg Med Chem; 2014 Oct; 22(19):5513-29. PubMed ID: 25139751
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Discovery of small-molecule modulators of the Sonic Hedgehog pathway.
    Schaefer GI; Perez JR; Duvall JR; Stanton BZ; Shamji AF; Schreiber SL
    J Am Chem Soc; 2013 Jul; 135(26):9675-80. PubMed ID: 23725514
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway.
    Duplan V; Serba C; Garcia J; Valot G; Barluenga S; Hoerlé M; Cuendet M; Winssinger N
    Org Biomol Chem; 2014 Jan; 12(2):370-5. PubMed ID: 24263232
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and preliminary biological evaluation of a compound library of triazolylcyclitols.
    Carrau G; Drewes CC; Shimada AL; Bertucci A; Farsky SH; Stefani HA; Gonzalez D
    Bioorg Med Chem; 2013 Jul; 21(14):4225-32. PubMed ID: 23721916
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Discovery of inhibitors of the Wnt and Hedgehog signaling pathways through the catalytic enantioselective synthesis of an iridoid-inspired compound collection.
    Takayama H; Jia ZJ; Kremer L; Bauer JO; Strohmann C; Ziegler S; Antonchick AP; Waldmann H
    Angew Chem Int Ed Engl; 2013 Nov; 52(47):12404-8. PubMed ID: 24115579
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51.
    Lv W; Budke B; Pawlowski M; Connell PP; Kozikowski AP
    J Med Chem; 2016 May; 59(10):4511-25. PubMed ID: 27049177
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Introduction of fluorine to phenyl group of 4-(2-pyrimidinylamino)benzamides leading to a series of potent hedgehog signaling pathway inhibitors.
    Xin M; Zhang L; Wen J; Shen H; Zhao X; Jin Q; Tang F
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3259-3263. PubMed ID: 28642101
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics.
    Maschinot CA; Pace JR; Hadden MK
    Curr Med Chem; 2015; 22(35):4033-57. PubMed ID: 26310919
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Small molecule Hedgehog pathway antagonists.
    Trinh TN; McLaughlin EA; Gordon CP; Bernstein IR; Pye VJ; Redgrove KA; McCluskey A
    Org Biomol Chem; 2017 Apr; 15(14):3046-3059. PubMed ID: 28318003
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Identification and characterization of benzo[d]oxazol-2(3H)-one derivatives as the first potent and selective small-molecule inhibitors of chromodomain protein CDYL.
    Yang L; Liu Y; Fan M; Zhu G; Jin H; Liang J; Liu Z; Huang Z; Zhang L
    Eur J Med Chem; 2019 Nov; 182():111656. PubMed ID: 31494467
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Small lipidated anti-obesity compounds derived from neuromedin U.
    Micewicz ED; Bahattab OS; Willars GB; Waring AJ; Navab M; Whitelegge JP; McBride WH; Ruchala P
    Eur J Med Chem; 2015 Aug; 101():616-26. PubMed ID: 26204509
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Small-molecule procaspase activators identified using fluorescence polarization.
    Vickers CJ; González-Páez GE; Umotoy JC; Cayanan-Garrett C; Brown SJ; Wolan DW
    Chembiochem; 2013 Aug; 14(12):1419-22. PubMed ID: 23836614
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.
    Němec V; Hylsová M; Maier L; Flegel J; Sievers S; Ziegler S; Schröder M; Berger BT; Chaikuad A; Valčíková B; Uldrijan S; Drápela S; Souček K; Waldmann H; Knapp S; Paruch K
    Angew Chem Int Ed Engl; 2019 Jan; 58(4):1062-1066. PubMed ID: 30569600
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of bromophenol thiohydantoin as an inhibitor of DisA, a c-di-AMP synthase, from a 1000 compound library, using the coralyne assay.
    Zheng Y; Zhou J; Sayre DA; Sintim HO
    Chem Commun (Camb); 2014 Oct; 50(76):11234-7. PubMed ID: 25116237
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Discovery and structure-activity relationships of pyrazolodiazepine derivatives as the first small molecule agonists of the Drosophila sex peptide receptor.
    Kim JH; Jeong PH; Lee JY; Lee JH; Kim YJ; Kim YC
    Bioorg Med Chem; 2015 Apr; 23(8):1808-16. PubMed ID: 25797164
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design and synthesis of small molecule agonists of EphA2 receptor.
    Petty A; Idippily N; Bobba V; Geldenhuys WJ; Zhong B; Su B; Wang B
    Eur J Med Chem; 2018 Jan; 143():1261-1276. PubMed ID: 29128116
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions.
    Haniff HS; Knerr L; Liu X; Crynen G; Boström J; Abegg D; Adibekian A; Lekah E; Wang KW; Cameron MD; Yildirim I; Lemurell M; Disney MD
    Nat Chem; 2020 Oct; 12(10):952-961. PubMed ID: 32839603
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Drugging Hedgehog: signaling the pathway to translation.
    Carney TJ; Ingham PW
    BMC Biol; 2013 Apr; 11():37. PubMed ID: 23587183
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design and development of FGF-23 antagonists: Definition of the pharmacophore and initial structure-activity relationships probed by synthetic analogues.
    Downs RP; Xiao Z; Ikedionwu MO; Cleveland JW; Lin Chin A; Cafferty AE; Darryl Quarles L; Carrick JD
    Bioorg Med Chem; 2021 Jan; 29():115877. PubMed ID: 33232874
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 4.