BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 22988061)

  • 1. The orally active glutamate carboxypeptidase II inhibitor E2072 exhibits sustained nerve exposure and attenuates peripheral neuropathy.
    Wozniak KM; Wu Y; Vornov JJ; Lapidus R; Rais R; Rojas C; Tsukamoto T; Slusher BS
    J Pharmacol Exp Ther; 2012 Dec; 343(3):746-54. PubMed ID: 22988061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reversible disulfide formation of the glutamate carboxypeptidase II inhibitor E2072 results in prolonged systemic exposures in vivo.
    Rais R; Hoover R; Wozniak K; Rudek MA; Tsukamoto T; Alt J; Rojas C; Slusher BS
    Drug Metab Dispos; 2012 Dec; 40(12):2315-23. PubMed ID: 22949627
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetics and pharmacodynamics of the glutamate carboxypeptidase II inhibitor 2-MPPA show prolonged alleviation of neuropathic pain through an indirect mechanism.
    Vornov JJ; Wozniak KM; Wu Y; Rojas C; Rais R; Slusher BS
    J Pharmacol Exp Ther; 2013 Sep; 346(3):406-13. PubMed ID: 23776202
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The preventive and therapeutic effects of GCPII (NAALADase) inhibition on painful and sensory diabetic neuropathy.
    Zhang W; Murakawa Y; Wozniak KM; Slusher B; Sima AA
    J Neurol Sci; 2006 Sep; 247(2):217-23. PubMed ID: 16780883
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A single dose of liposome-encapsulated oxymorphone or morphine provides long-term analgesia in an animal model of neuropathic pain.
    Smith LJ; Krugner-Higby L; Clark M; Wendland A; Heath TD
    Comp Med; 2003 Jun; 53(3):280-7. PubMed ID: 12868573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and pharmacological evaluation of glutamate carboxypeptidase II (GCPII) inhibitors based on thioalkylbenzoic acid scaffolds.
    Stoermer D; Vitharana D; Hin N; Delahanty G; Duvall B; Ferraris DV; Grella BS; Hoover R; Rojas C; Shanholtz MK; Smith KP; Stathis M; Wu Y; Wozniak KM; Slusher BS; Tsukamoto T
    J Med Chem; 2012 Jun; 55(12):5922-32. PubMed ID: 22642259
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Goshajinkigan reduces oxaliplatin-induced peripheral neuropathy without affecting anti-tumour efficacy in rodents.
    Ushio S; Egashira N; Sada H; Kawashiri T; Shirahama M; Masuguchi K; Oishi R
    Eur J Cancer; 2012 Jun; 48(9):1407-13. PubMed ID: 21907570
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Spinal administration of a delta opioid receptor agonist attenuates hyperalgesia and allodynia in a rat model of neuropathic pain.
    Holdridge SV; Cahill CM
    Eur J Pain; 2007 Aug; 11(6):685-93. PubMed ID: 17175187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxaliplatin-induced neuropathy in the rat: involvement of oxalate in cold hyperalgesia but not mechanical allodynia.
    Sakurai M; Egashira N; Kawashiri T; Yano T; Ikesue H; Oishi R
    Pain; 2009 Dec; 147(1-3):165-74. PubMed ID: 19782472
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diphenyl diselenide attenuates acute thermal hyperalgesia and persistent inflammatory and neuropathic pain behavior in mice.
    Savegnago L; Jesse CR; Pinto LG; Rocha JB; Nogueira CW
    Brain Res; 2007 Oct; 1175():54-9. PubMed ID: 17888416
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxaliplatin acts on IB4-positive nociceptors to induce an oxidative stress-dependent acute painful peripheral neuropathy.
    Joseph EK; Chen X; Bogen O; Levine JD
    J Pain; 2008 May; 9(5):463-72. PubMed ID: 18359667
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of synthetic eel calcitonin, elcatonin, on cold and mechanical allodynia induced by oxaliplatin and paclitaxel in rats.
    Aoki M; Mori A; Nakahara T; Sakamoto K; Ishii K
    Eur J Pharmacol; 2012 Dec; 696(1-3):62-9. PubMed ID: 23001015
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor.
    Majer P; Jackson PF; Delahanty G; Grella BS; Ko YS; Li W; Liu Q; Maclin KM; Poláková J; Shaffer KA; Stoermer D; Vitharana D; Wang EY; Zakrzewski A; Rojas C; Slusher BS; Wozniak KM; Burak E; Limsakun T; Tsukamoto T
    J Med Chem; 2003 May; 46(10):1989-96. PubMed ID: 12723961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuroprotective effect of saponin rich extract of Acorus calamus L. in rat model of chronic constriction injury (CCI) of sciatic nerve-induced neuropathic pain.
    Muthuraman A; Singh N
    J Ethnopharmacol; 2012 Aug; 142(3):723-31. PubMed ID: 22706151
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of urea-based inhibitors as active site probes of glutamate carboxypeptidase II: efficacy as analgesic agents.
    Kozikowski AP; Zhang J; Nan F; Petukhov PA; Grajkowska E; Wroblewski JT; Yamamoto T; Bzdega T; Wroblewska B; Neale JH
    J Med Chem; 2004 Mar; 47(7):1729-38. PubMed ID: 15027864
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy.
    Bordet T; Buisson B; Michaud M; Abitbol JL; Marchand F; Grist J; Andriambeloson E; Malcangio M; Pruss RM
    J Pharmacol Exp Ther; 2008 Aug; 326(2):623-32. PubMed ID: 18492948
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of extracellular signal-regulated kinase in sciatic nerve contributes to neuropathic pain after partial sciatic nerve ligation in mice.
    Kiguchi N; Maeda T; Kobayashi Y; Fukazawa Y; Kishioka S
    Anesth Analg; 2009 Oct; 109(4):1305-11. PubMed ID: 19762761
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of amitriptyline and gabapentin on bilateral hyperalgesia observed in an animal model of unilateral axotomy.
    Yasuda T; Miki S; Yoshinaga N; Senba E
    Pain; 2005 May; 115(1-2):161-70. PubMed ID: 15836979
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model.
    Yamamoto T; Hirasawa S; Wroblewska B; Grajkowska E; Zhou J; Kozikowski A; Wroblewski J; Neale JH
    Eur J Neurosci; 2004 Jul; 20(2):483-94. PubMed ID: 15233757
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.
    Dudhgaonkar SP; Tandan SK; Kumar D; Naik AK; Raviprakash V
    Eur J Pain; 2007 Jul; 11(5):528-34. PubMed ID: 16920373
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.