171 related articles for article (PubMed ID: 22991046)
1. State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1.
Rapedius M; Schmidt MR; Sharma C; Stansfeld PJ; Sansom MS; Baukrowitz T; Tucker SJ
Channels (Austin); 2012; 6(6):473-8. PubMed ID: 22991046
[TBL] [Abstract][Full Text] [Related]
2. The pore structure and gating mechanism of K2P channels.
Piechotta PL; Rapedius M; Stansfeld PJ; Bollepalli MK; Ehrlich G; Andres-Enguix I; Fritzenschaft H; Decher N; Sansom MS; Tucker SJ; Baukrowitz T
EMBO J; 2011 Aug; 30(17):3607-19. PubMed ID: 21822218
[TBL] [Abstract][Full Text] [Related]
3. Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K
Bustos D; Bedoya M; Ramírez D; Concha G; Zúñiga L; Decher N; Hernández-Rodríguez EW; Sepúlveda FV; Martínez L; González W
Int J Mol Sci; 2020 Jan; 21(2):. PubMed ID: 31947679
[TBL] [Abstract][Full Text] [Related]
4. Markov modeling reveals novel intracellular modulation of the human TREK-2 selectivity filter.
Harrigan MP; McKiernan KA; Shanmugasundaram V; Denny RA; Pande VS
Sci Rep; 2017 Apr; 7(1):632. PubMed ID: 28377596
[TBL] [Abstract][Full Text] [Related]
5. TRESK background potassium channel is not gated at the helix bundle crossing near the cytoplasmic end of the pore.
Lengyel M; Czirják G; Enyedi P
PLoS One; 2018; 13(5):e0197622. PubMed ID: 29763475
[TBL] [Abstract][Full Text] [Related]
6. K
Lolicato M; Arrigoni C; Mori T; Sekioka Y; Bryant C; Clark KA; Minor DL
Nature; 2017 Jul; 547(7663):364-368. PubMed ID: 28693035
[TBL] [Abstract][Full Text] [Related]
7. External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter.
Ma XY; Yu JM; Zhang SZ; Liu XY; Wu BH; Wei XL; Yan JQ; Sun HL; Yan HT; Zheng JQ
J Biol Chem; 2011 Nov; 286(46):39813-22. PubMed ID: 21965685
[TBL] [Abstract][Full Text] [Related]
8. 'C-type' closed state and gating mechanisms of K2P channels revealed by conformational changes of the TREK-1 channel.
Zhang Q; Fu J; Zhang S; Guo P; Liu S; Shen J; Guo J; Yang H
J Mol Cell Biol; 2022 Apr; 14(1):. PubMed ID: 35022758
[TBL] [Abstract][Full Text] [Related]
9. Gating, Regulation, and Structure in K2P K+ Channels: In Varietate Concordia?
Niemeyer MI; Cid LP; González W; Sepúlveda FV
Mol Pharmacol; 2016 Sep; 90(3):309-17. PubMed ID: 27268784
[TBL] [Abstract][Full Text] [Related]
10. Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.
Aryal P; Jarerattanachat V; Clausen MV; Schewe M; McClenaghan C; Argent L; Conrad LJ; Dong YY; Pike ACW; Carpenter EP; Baukrowitz T; Sansom MSP; Tucker SJ
Structure; 2017 May; 25(5):708-718.e2. PubMed ID: 28392258
[TBL] [Abstract][Full Text] [Related]
11. Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states.
McClenaghan C; Schewe M; Aryal P; Carpenter EP; Baukrowitz T; Tucker SJ
J Gen Physiol; 2016 Jun; 147(6):497-505. PubMed ID: 27241700
[TBL] [Abstract][Full Text] [Related]
12. The effects of stretch activation on ionic selectivity of the TREK-2 K2P K
Nematian-Ardestani E; Jarerattanachat V; Aryal P; Sansom MSP; Tucker SJ
Channels (Austin); 2017 Sep; 11(5):482-486. PubMed ID: 28723241
[TBL] [Abstract][Full Text] [Related]
13. K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
Dong YY; Pike AC; Mackenzie A; McClenaghan C; Aryal P; Dong L; Quigley A; Grieben M; Goubin S; Mukhopadhyay S; Ruda GF; Clausen MV; Cao L; Brennan PE; Burgess-Brown NA; Sansom MS; Tucker SJ; Carpenter EP
Science; 2015 Mar; 347(6227):1256-9. PubMed ID: 25766236
[TBL] [Abstract][Full Text] [Related]
14. State-independent block of BK channels by an intracellular quaternary ammonium.
Wilkens CM; Aldrich RW
J Gen Physiol; 2006 Sep; 128(3):347-64. PubMed ID: 16940557
[TBL] [Abstract][Full Text] [Related]
15. Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate.
Contreras JE; Holmgren M
J Gen Physiol; 2006 May; 127(5):481-94. PubMed ID: 16606688
[TBL] [Abstract][Full Text] [Related]
16. Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate.
Proks P; Schewe M; Conrad LJ; Rao S; Rathje K; Rödström KEJ; Carpenter EP; Baukrowitz T; Tucker SJ
J Gen Physiol; 2021 Aug; 153(8):. PubMed ID: 34032848
[TBL] [Abstract][Full Text] [Related]
17. Gating of the kir2.1 channel at the bundle crossing region by intracellular spermine and other cations.
Huang CW; Kuo CC
J Cell Physiol; 2014 Nov; 229(11):1703-21. PubMed ID: 24633623
[TBL] [Abstract][Full Text] [Related]
18. A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel.
Aryal P; Abd-Wahab F; Bucci G; Sansom MS; Tucker SJ
Nat Commun; 2014 Jul; 5():4377. PubMed ID: 25001086
[TBL] [Abstract][Full Text] [Related]
19. Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels.
Bruening-Wright A; Lee WS; Adelman JP; Maylie J
J Gen Physiol; 2007 Dec; 130(6):601-10. PubMed ID: 17998394
[TBL] [Abstract][Full Text] [Related]
20. Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel.
Aryal P; Abd-Wahab F; Bucci G; Sansom MS; Tucker SJ
Channels (Austin); 2015; 9(1):44-9. PubMed ID: 25487004
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]