222 related articles for article (PubMed ID: 22991240)
1. Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption.
Martínez VS; Dietmair S; Quek LE; Hodson MP; Gray P; Nielsen LK
Biotechnol Bioeng; 2013 Feb; 110(2):660-6. PubMed ID: 22991240
[TBL] [Abstract][Full Text] [Related]
2. Comparative metabolite analysis to understand lactate metabolism shift in Chinese hamster ovary cell culture process.
Luo J; Vijayasankaran N; Autsen J; Santuray R; Hudson T; Amanullah A; Li F
Biotechnol Bioeng; 2012 Jan; 109(1):146-56. PubMed ID: 21964570
[TBL] [Abstract][Full Text] [Related]
3. Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases.
Zhou M; Crawford Y; Ng D; Tung J; Pynn AF; Meier A; Yuk IH; Vijayasankaran N; Leach K; Joly J; Snedecor B; Shen A
J Biotechnol; 2011 Apr; 153(1-2):27-34. PubMed ID: 21392546
[TBL] [Abstract][Full Text] [Related]
4. Insights into pH-induced metabolic switch by flux balance analysis.
Ivarsson M; Noh H; Morbidelli M; Soos M
Biotechnol Prog; 2015; 31(2):347-57. PubMed ID: 25906421
[TBL] [Abstract][Full Text] [Related]
5. Probing the metabolism of an inducible mammalian expression system using extracellular isotopomer analysis.
Sheikholeslami Z; Jolicoeur M; Henry O
J Biotechnol; 2013 Apr; 164(4):469-78. PubMed ID: 23403402
[TBL] [Abstract][Full Text] [Related]
6. Metabolic analysis of antibody producing CHO cells in fed-batch production.
Dean J; Reddy P
Biotechnol Bioeng; 2013 Jun; 110(6):1735-47. PubMed ID: 23296898
[TBL] [Abstract][Full Text] [Related]
7. Considerations on the lactate consumption by CHO cells in the presence of galactose.
Altamirano C; Illanes A; Becerra S; Cairó JJ; Gòdia F
J Biotechnol; 2006 Oct; 125(4):547-56. PubMed ID: 16822573
[TBL] [Abstract][Full Text] [Related]
8. Elucidating the role of copper in CHO cell energy metabolism using (13)C metabolic flux analysis.
Nargund S; Qiu J; Goudar CT
Biotechnol Prog; 2015; 31(5):1179-86. PubMed ID: 26097228
[TBL] [Abstract][Full Text] [Related]
9. A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism.
Ma N; Ellet J; Okediadi C; Hermes P; McCormick E; Casnocha S
Biotechnol Prog; 2009; 25(5):1353-63. PubMed ID: 19637321
[TBL] [Abstract][Full Text] [Related]
10. Multiplicity of steady states in glycolysis and shift of metabolic state in cultured mammalian cells.
Mulukutla BC; Yongky A; Grimm S; Daoutidis P; Hu WS
PLoS One; 2015; 10(3):e0121561. PubMed ID: 25806512
[TBL] [Abstract][Full Text] [Related]
11. Monitoring Chinese hamster ovary cell culture by the analysis of glucose and lactate metabolism.
Tsao YS; Cardoso AG; Condon RG; Voloch M; Lio P; Lagos JC; Kearns BG; Liu Z
J Biotechnol; 2005 Aug; 118(3):316-27. PubMed ID: 16019100
[TBL] [Abstract][Full Text] [Related]
12. Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity.
Zagari F; Jordan M; Stettler M; Broly H; Wurm FM
N Biotechnol; 2013 Jan; 30(2):238-45. PubMed ID: 22683938
[TBL] [Abstract][Full Text] [Related]
13. A kinetic-metabolic model based on cell energetic state: study of CHO cell behavior under Na-butyrate stimulation.
Ghorbaniaghdam A; Henry O; Jolicoeur M
Bioprocess Biosyst Eng; 2013 Apr; 36(4):469-87. PubMed ID: 22976819
[TBL] [Abstract][Full Text] [Related]
14. Combinatorial engineering of ldh-a and bcl-2 for reducing lactate production and improving cell growth in dihydrofolate reductase-deficient Chinese hamster ovary cells.
Jeon MK; Yu DY; Lee GM
Appl Microbiol Biotechnol; 2011 Nov; 92(4):779-90. PubMed ID: 21792592
[TBL] [Abstract][Full Text] [Related]
15. Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis.
Strigun A; Wahrheit J; Niklas J; Heinzle E; Noor F
Toxicol Sci; 2012 Feb; 125(2):595-606. PubMed ID: 22048646
[TBL] [Abstract][Full Text] [Related]
16. Metabolic flux analysis of CHO cell metabolism in the late non-growth phase.
Sengupta N; Rose ST; Morgan JA
Biotechnol Bioeng; 2011 Jan; 108(1):82-92. PubMed ID: 20672285
[TBL] [Abstract][Full Text] [Related]
17. Influence of hypoxia and an acidic environment on the metabolism and viability of cultured cells: potential implications for cell death in tumors.
Rotin D; Robinson B; Tannock IF
Cancer Res; 1986 Jun; 46(6):2821-6. PubMed ID: 3698008
[TBL] [Abstract][Full Text] [Related]
18. Correlation of antibody production rate with glucose and lactate metabolism in Chinese hamster ovary cells.
Chen F; Ye Z; Zhao L; Liu X; Fan L; Tan WS
Biotechnol Lett; 2012 Mar; 34(3):425-32. PubMed ID: 22105551
[TBL] [Abstract][Full Text] [Related]
19. Metabolic flux analysis of a phenol producing mutant of Pseudomonas putida S12: verification and complementation of hypotheses derived from transcriptomics.
Wierckx N; Ruijssenaars HJ; de Winde JH; Schmid A; Blank LM
J Biotechnol; 2009 Aug; 143(2):124-9. PubMed ID: 19560494
[TBL] [Abstract][Full Text] [Related]
20. Combining mechanistic and data-driven approaches to gain process knowledge on the control of the metabolic shift to lactate uptake in a fed-batch CHO process.
Zalai D; Koczka K; Párta L; Wechselberger P; Klein T; Herwig C
Biotechnol Prog; 2015; 31(6):1657-68. PubMed ID: 26439213
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]