194 related articles for article (PubMed ID: 22995600)
1. Structural biology of dengue virus enzymes: towards rational design of therapeutics.
Noble CG; Shi PY
Antiviral Res; 2012 Nov; 96(2):115-26. PubMed ID: 22995600
[TBL] [Abstract][Full Text] [Related]
2. Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design.
Lim SP; Noble CG; Nilar S; Shi PY; Yokokawa F
Adv Exp Med Biol; 2018; 1062():187-198. PubMed ID: 29845534
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of dengue virus polymerase by blocking of the RNA tunnel.
Niyomrattanakit P; Chen YL; Dong H; Yin Z; Qing M; Glickman JF; Lin K; Mueller D; Voshol H; Lim JY; Nilar S; Keller TH; Shi PY
J Virol; 2010 Jun; 84(11):5678-86. PubMed ID: 20237086
[TBL] [Abstract][Full Text] [Related]
4. Small molecule inhibitors that selectively block dengue virus methyltransferase.
Lim SP; Sonntag LS; Noble C; Nilar SH; Ng RH; Zou G; Monaghan P; Chung KY; Dong H; Liu B; Bodenreider C; Lee G; Ding M; Chan WL; Wang G; Jian YL; Chao AT; Lescar J; Yin Z; Vedananda TR; Keller TH; Shi PY
J Biol Chem; 2011 Feb; 286(8):6233-40. PubMed ID: 21147775
[TBL] [Abstract][Full Text] [Related]
5. Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
Lim SP; Noble CG; Seh CC; Soh TS; El Sahili A; Chan GK; Lescar J; Arora R; Benson T; Nilar S; Manjunatha U; Wan KF; Dong H; Xie X; Shi PY; Yokokawa F
PLoS Pathog; 2016 Aug; 12(8):e1005737. PubMed ID: 27500641
[TBL] [Abstract][Full Text] [Related]
6. Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.
Barral K; Sallamand C; Petzold C; Coutard B; Collet A; Thillier Y; Zimmermann J; Vasseur JJ; Canard B; Rohayem J; Debart F; Decroly E
Antiviral Res; 2013 Sep; 99(3):292-300. PubMed ID: 23769894
[TBL] [Abstract][Full Text] [Related]
7. 3',5'Di-O-trityluridine inhibits in vitro flavivirus replication.
De Burghgraeve T; Selisko B; Kaptein S; Chatelain G; Leyssen P; Debing Y; Jacobs M; Van Aerschot A; Canard B; Neyts J
Antiviral Res; 2013 May; 98(2):242-7. PubMed ID: 23470860
[TBL] [Abstract][Full Text] [Related]
8. Crystal structure of Dengue virus NS3 protease in complex with a Bowman-Birk inhibitor: implications for flaviviral polyprotein processing and drug design.
Murthy HM; Judge K; DeLucas L; Padmanabhan R
J Mol Biol; 2000 Aug; 301(4):759-67. PubMed ID: 10966782
[TBL] [Abstract][Full Text] [Related]
9. Narasin, a novel antiviral compound that blocks dengue virus protein expression.
Low JS; Wu KX; Chen KC; Ng MM; Chu JJ
Antivir Ther; 2011; 16(8):1203-18. PubMed ID: 22155902
[TBL] [Abstract][Full Text] [Related]
10. The dengue virus NS5 protein as a target for drug discovery.
Lim SP; Noble CG; Shi PY
Antiviral Res; 2015 Jul; 119():57-67. PubMed ID: 25912817
[TBL] [Abstract][Full Text] [Related]
11. Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase.
Xu HT; Colby-Germinario SP; Hassounah S; Quashie PK; Han Y; Oliveira M; Stranix BR; Wainberg MA
Antimicrob Agents Chemother; 2016 Jan; 60(1):600-8. PubMed ID: 26574011
[TBL] [Abstract][Full Text] [Related]
12. The flavivirus polymerase as a target for drug discovery.
Malet H; Massé N; Selisko B; Romette JL; Alvarez K; Guillemot JC; Tolou H; Yap TL; Vasudevan S; Lescar J; Canard B
Antiviral Res; 2008 Oct; 80(1):23-35. PubMed ID: 18611413
[TBL] [Abstract][Full Text] [Related]
13. Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery.
Coutard B; Decroly E; Li C; Sharff A; Lescar J; Bricogne G; Barral K
Antiviral Res; 2014 Jun; 106():61-70. PubMed ID: 24704437
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture.
Steuer C; Gege C; Fischl W; Heinonen KH; Bartenschlager R; Klein CD
Bioorg Med Chem; 2011 Jul; 19(13):4067-74. PubMed ID: 21641807
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity relationship study of biflavonoids on the Dengue virus polymerase DENV-NS5 RdRp.
Coulerie P; Nour M; Maciuk A; Eydoux C; Guillemot JC; Lebouvier N; Hnawia E; Leblanc K; Lewin G; Canard B; Figadère B
Planta Med; 2013 Sep; 79(14):1313-8. PubMed ID: 23929244
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine.
Noble CG; Li SH; Dong H; Chew SH; Shi PY
Antiviral Res; 2014 Nov; 111():78-81. PubMed ID: 25241250
[TBL] [Abstract][Full Text] [Related]
17. Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target.
Lescar J; Luo D; Xu T; Sampath A; Lim SP; Canard B; Vasudevan SG
Antiviral Res; 2008 Nov; 80(2):94-101. PubMed ID: 18674567
[TBL] [Abstract][Full Text] [Related]
18. Identification of dengue viral RNA-dependent RNA polymerase inhibitor using computational fragment-based approaches and molecular dynamics study.
Anusuya S; Velmurugan D; Gromiha MM
J Biomol Struct Dyn; 2016 Jul; 34(7):1512-32. PubMed ID: 26262439
[TBL] [Abstract][Full Text] [Related]
19. Biochemical and genetic characterization of dengue virus methyltransferase.
Dong H; Chang DC; Xie X; Toh YX; Chung KY; Zou G; Lescar J; Lim SP; Shi PY
Virology; 2010 Sep; 405(2):568-78. PubMed ID: 20655081
[TBL] [Abstract][Full Text] [Related]
20. Strategies for development of Dengue virus inhibitors.
Noble CG; Chen YL; Dong H; Gu F; Lim SP; Schul W; Wang QY; Shi PY
Antiviral Res; 2010 Mar; 85(3):450-62. PubMed ID: 20060421
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
