BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 22999299)

  • 1. The ΔF508-CFTR mutation inhibits wild-type CFTR processing and function when co-expressed in human airway epithelia and in mouse nasal mucosa.
    Tucker TA; Fortenberry JA; Zsembery A; Schwiebert LM; Schwiebert EM
    BMC Physiol; 2012 Sep; 12():12. PubMed ID: 22999299
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endogenous surface expression of ΔF508-CFTR mediates cAMP-stimulated Cl(-) current in CFTR(ΔF508/ΔF508) pig thyroid epithelial cells.
    Li Y; Ganta S; Fong P
    Exp Physiol; 2012 Jan; 97(1):115-24. PubMed ID: 21948195
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia.
    Kreda SM; Mall M; Mengos A; Rochelle L; Yankaskas J; Riordan JR; Boucher RC
    Mol Biol Cell; 2005 May; 16(5):2154-67. PubMed ID: 15716351
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative processing and function of human and ferret cystic fibrosis transmembrane conductance regulator.
    Fisher JT; Liu X; Yan Z; Luo M; Zhang Y; Zhou W; Lee BJ; Song Y; Guo C; Wang Y; Lukacs GL; Engelhardt JF
    J Biol Chem; 2012 Jun; 287(26):21673-85. PubMed ID: 22570484
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spliceosome-mediated RNA trans-splicing with recombinant adeno-associated virus partially restores cystic fibrosis transmembrane conductance regulator function to polarized human cystic fibrosis airway epithelial cells.
    Liu X; Luo M; Zhang LN; Yan Z; Zak R; Ding W; Mansfield SG; Mitchell LG; Engelhardt JF
    Hum Gene Ther; 2005 Sep; 16(9):1116-23. PubMed ID: 16149910
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Purinergic signaling underlies CFTR control of human airway epithelial cell volume.
    Braunstein GM; Zsembery A; Tucker TA; Schwiebert EM
    J Cyst Fibros; 2004 Jun; 3(2):99-117. PubMed ID: 15463893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cystic fibrosis transmembrane conductance regulator-mRNA delivery: a novel alternative for cystic fibrosis gene therapy.
    Bangel-Ruland N; Tomczak K; Fernández Fernández E; Leier G; Leciejewski B; Rudolph C; Rosenecker J; Weber WM
    J Gene Med; 2013; 15(11-12):414-26. PubMed ID: 24123772
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel amino-carbonitrile-pyrazole identified in a small molecule screen activates wild-type and ΔF508 cystic fibrosis transmembrane conductance regulator in the absence of a cAMP agonist.
    Namkung W; Park J; Seo Y; Verkman AS
    Mol Pharmacol; 2013 Sep; 84(3):384-92. PubMed ID: 23788656
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of cystic fibrosis transmembrane conductance regulator and DeltaF508CFTR on inflammatory response, ER stress, and Ca2+ of airway epithelia.
    Hybiske K; Fu Z; Schwarzer C; Tseng J; Do J; Huang N; Machen TE
    Am J Physiol Lung Cell Mol Physiol; 2007 Nov; 293(5):L1250-60. PubMed ID: 17827250
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells.
    Suaud L; Miller K; Alvey L; Yan W; Robay A; Kebler C; Kreindler JL; Guttentag S; Hubbard MJ; Rubenstein RC
    J Biol Chem; 2011 Jun; 286(24):21239-53. PubMed ID: 21525008
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of the cystic fibrosis transmembrane conductance regulator by the flavonoid quercetin: potential use as a biomarker of ΔF508 cystic fibrosis transmembrane conductance regulator rescue.
    Pyle LC; Fulton JC; Sloane PA; Backer K; Mazur M; Prasain J; Barnes S; Clancy JP; Rowe SM
    Am J Respir Cell Mol Biol; 2010 Nov; 43(5):607-16. PubMed ID: 20042712
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bioelectric characterization of epithelia from neonatal CFTR knockout ferrets.
    Fisher JT; Tyler SR; Zhang Y; Lee BJ; Liu X; Sun X; Sui H; Liang B; Luo M; Xie W; Yi Y; Zhou W; Song Y; Keiser N; Wang K; de Jonge HR; Engelhardt JF
    Am J Respir Cell Mol Biol; 2013 Nov; 49(5):837-44. PubMed ID: 23782101
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells.
    Turner MJ; Sato Y; Thomas DY; Abbott-Banner K; Hanrahan JW
    Cell Physiol Biochem; 2021 Dec; 55(6):784-804. PubMed ID: 34936285
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers.
    Bebok Z; Collawn JF; Wakefield J; Parker W; Li Y; Varga K; Sorscher EJ; Clancy JP
    J Physiol; 2005 Dec; 569(Pt 2):601-15. PubMed ID: 16210354
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing.
    Liu X; Jiang Q; Mansfield SG; Puttaraju M; Zhang Y; Zhou W; Cohn JA; Garcia-Blanco MA; Mitchell LG; Engelhardt JF
    Nat Biotechnol; 2002 Jan; 20(1):47-52. PubMed ID: 11753361
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chaperone displacement from mutant cystic fibrosis transmembrane conductance regulator restores its function in human airway epithelia.
    Sun F; Mi Z; Condliffe SB; Bertrand CA; Gong X; Lu X; Zhang R; Latoche JD; Pilewski JM; Robbins PD; Frizzell RA
    FASEB J; 2008 Sep; 22(9):3255-63. PubMed ID: 18556464
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis.
    Fang D; West RH; Manson ME; Ruddy J; Jiang D; Previs SF; Sonawane ND; Burgess JD; Kelley TJ
    Respir Res; 2010 May; 11(1):61. PubMed ID: 20487541
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs.
    Ostedgaard LS; Meyerholz DK; Chen JH; Pezzulo AA; Karp PH; Rokhlina T; Ernst SE; Hanfland RA; Reznikov LR; Ludwig PS; Rogan MP; Davis GJ; Dohrn CL; Wohlford-Lenane C; Taft PJ; Rector MV; Hornick E; Nassar BS; Samuel M; Zhang Y; Richter SS; Uc A; Shilyansky J; Prather RS; McCray PB; Zabner J; Welsh MJ; Stoltz DA
    Sci Transl Med; 2011 Mar; 3(74):74ra24. PubMed ID: 21411740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sensitivity of chloride efflux vs. transepithelial measurements in mixed CF and normal airway epithelial cell populations.
    Illek B; Lei D; Fischer H; Gruenert DC
    Cell Physiol Biochem; 2010; 26(6):983-90. PubMed ID: 21220929
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Resveratrol ameliorates abnormalities of fluid and electrolyte secretion in a hypoxia-Induced model of acquired CFTR deficiency.
    Woodworth BA
    Laryngoscope; 2015 Oct; 125 Suppl 7(0 7):S1-S13. PubMed ID: 25946147
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.