BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 23000296)

  • 1. Novel multipotent phenylthiazole-tacrine hybrids for the inhibition of cholinesterase activity, β-amyloid aggregation and Ca²⁺ overload.
    Wang Y; Wang F; Yu JP; Jiang FC; Guan XL; Wang CM; Li L; Cao H; Li MX; Chen JG
    Bioorg Med Chem; 2012 Nov; 20(21):6513-22. PubMed ID: 23000296
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids.
    Huang L; Su T; Shan W; Luo Z; Sun Y; He F; Li X
    Bioorg Med Chem; 2012 May; 20(9):3038-48. PubMed ID: 22472046
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.
    Luo W; Li YP; He Y; Huang SL; Tan JH; Ou TM; Li D; Gu LQ; Huang ZS
    Bioorg Med Chem; 2011 Jan; 19(2):763-70. PubMed ID: 21211982
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, Aβ aggregation, and β-secretase.
    Sun Q; Peng DY; Yang SG; Zhu XL; Yang WC; Yang GF
    Bioorg Med Chem; 2014 Sep; 22(17):4784-91. PubMed ID: 25088549
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and evaluation of tacrine-flurbiprofen-nitrate trihybrids as novel anti-Alzheimer's disease agents.
    Chen Y; Sun J; Huang Z; Liao H; Peng S; Lehmann J; Zhang Y
    Bioorg Med Chem; 2013 May; 21(9):2462-70. PubMed ID: 23541836
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E; Sadeghpour H; Nadri H; Sakhteman A; Tüylü Küçükkılınç T; Miri R; Edraki N
    Bioorg Chem; 2019 Aug; 89():103006. PubMed ID: 31158577
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
    Xie SS; Wang XB; Li JY; Yang L; Kong LY
    Eur J Med Chem; 2013 Jun; 64():540-53. PubMed ID: 23685572
    [TBL] [Abstract][Full Text] [Related]  

  • 9. O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation.
    Mao F; Huang L; Luo Z; Liu A; Lu C; Xie Z; Li X
    Bioorg Med Chem; 2012 Oct; 20(19):5884-92. PubMed ID: 22944335
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tacrine-flurbiprofen hybrids as multifunctional drug candidates for the treatment of Alzheimer's disease.
    Chen Y; Sun J; Peng S; Liao H; Zhang Y; Lehmann J
    Arch Pharm (Weinheim); 2013 Dec; 346(12):865-71. PubMed ID: 24203864
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
    Chao X; He X; Yang Y; Zhou X; Jin M; Liu S; Cheng Z; Liu P; Wang Y; Yu J; Tan Y; Huang Y; Qin J; Rapposelli S; Pi R
    Bioorg Med Chem Lett; 2012 Oct; 22(20):6498-502. PubMed ID: 22981331
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
    Li SY; Wang XB; Xie SS; Jiang N; Wang KD; Yao HQ; Sun HB; Kong LY
    Eur J Med Chem; 2013 Nov; 69():632-46. PubMed ID: 24095756
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
    Di Pietro O; Pérez-Areales FJ; Juárez-Jiménez J; Espargaró A; Clos MV; Pérez B; Lavilla R; Sabaté R; Luque FJ; Muñoz-Torrero D
    Eur J Med Chem; 2014 Sep; 84():107-17. PubMed ID: 25016233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.
    Fernández-Bachiller MI; Pérez C; Monjas L; Rademann J; Rodríguez-Franco MI
    J Med Chem; 2012 Feb; 55(3):1303-17. PubMed ID: 22243648
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigation of the role of linker moieties in bifunctional tacrine hybrids.
    Eckroat TJ; Green KD; Reed RA; Bornstein JJ; Garneau-Tsodikova S
    Bioorg Med Chem; 2013 Jun; 21(12):3614-23. PubMed ID: 23535563
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
    Keri RS; Quintanova C; Marques SM; Esteves AR; Cardoso SM; Santos MA
    Bioorg Med Chem; 2013 Aug; 21(15):4559-69. PubMed ID: 23768661
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
    Tang H; Zhao LZ; Zhao HT; Huang SL; Zhong SM; Qin JK; Chen ZF; Huang ZS; Liang H
    Eur J Med Chem; 2011 Oct; 46(10):4970-9. PubMed ID: 21871694
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease.
    Zhang C; Du QY; Chen LD; Wu WH; Liao SY; Yu LH; Liang XT
    Eur J Med Chem; 2016 Jun; 116():200-209. PubMed ID: 27061983
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
    Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.