These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 23009633)

  • 1. Binding processes determine the stereoselective intestinal and hepatic extraction of verapamil in vivo.
    Thörn HA; Sjögren E; Dickinson PA; Lennernäs H
    Mol Pharm; 2012 Nov; 9(11):3034-45. PubMed ID: 23009633
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver: important for the mechanistic understanding of first-pass drug-drug interactions.
    Thörn HA; Hedeland M; Bondesson U; Knutson L; Yasin M; Dickinson P; Lennernäs H
    Drug Metab Dispos; 2009 Nov; 37(11):2186-96. PubMed ID: 19687151
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A semi-physiologically-based pharmacokinetic model characterizing mechanism-based auto-inhibition to predict stereoselective pharmacokinetics of verapamil and its metabolite norverapamil in human.
    Wang J; Xia S; Xue W; Wang D; Sai Y; Liu L; Liu X
    Eur J Pharm Sci; 2013 Nov; 50(3-4):290-302. PubMed ID: 23916407
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PBPK modeling to unravel nonlinear pharmacokinetics of verapamil to estimate the fractional clearance for verapamil N-demethylation in the recirculating rat liver preparation.
    Yang QJ; Si L; Tang H; Sveigaard HH; Chow EC; Pang KS
    Drug Metab Dispos; 2015 Apr; 43(4):631-45. PubMed ID: 25650380
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reversal of stereoselectivity in the hepatic availability of verapamil in isolated perfused rat livers. Role of protein binding.
    Mehvar R; Reynolds J
    Drug Metab Dispos; 1996 Oct; 24(10):1088-94. PubMed ID: 8894509
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enantioselective distribution of verapamil and norverapamil into human and rat erythrocytes: the role of plasma protein binding.
    Robinson MA; Mehvar R
    Biopharm Drug Dispos; 1996 Oct; 17(7):577-87. PubMed ID: 8894116
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs.
    Sjögren E; Hedeland M; Bondesson U; Lennernäs H
    Eur J Pharm Sci; 2014 Jun; 57():214-23. PubMed ID: 24075962
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacokinetic interaction between verapamil and metoprolol in the dog. Stereochemical aspects.
    Murthy SS; Nelson WL; Shen DD; Power JM; Cahill CM; McLean AJ
    Drug Metab Dispos; 1991; 19(6):1093-100. PubMed ID: 1687016
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo investigation in pigs of intestinal absorption, hepatobiliary disposition, and metabolism of the 5α-reductase inhibitor finasteride and the effects of coadministered ketoconazole.
    Lundahl A; Hedeland M; Bondesson U; Lennernäs H
    Drug Metab Dispos; 2011 May; 39(5):847-57. PubMed ID: 21317368
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin.
    Fromm MF; Busse D; Kroemer HK; Eichelbaum M
    Hepatology; 1996 Oct; 24(4):796-801. PubMed ID: 8855178
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Input rate-dependent stereoselective pharmacokinetics. Experimental evidence in verapamil-infused isolated rat livers.
    Mehvar R; Reynolds J
    Drug Metab Dispos; 1995 Jun; 23(6):637-41. PubMed ID: 7587945
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differentiation of gut and hepatic first-pass loss of verapamil in intestinal and vascular access-ported (IVAP) rabbits.
    Kunta JR; Lee SH; Perry BA; Lee YH; Sinko PJ
    Drug Metab Dispos; 2004 Nov; 32(11):1293-8. PubMed ID: 15304428
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enantioselective kinetics of verapamil and norverapamil in isolated perfused rat livers.
    Mehvar R; Reynolds JM; Robinson MA; Longstreth JA
    Pharm Res; 1994 Dec; 11(12):1815-9. PubMed ID: 7899248
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantitative analysis of pharmacokinetic profiles of verapamil and drug-drug interactions induced by a CYP inhibitor using a stable isotope-labeled compound.
    Kataoka M; Kojima C; Ueda K; Minami K; Higashino H; Sakuma S; Togashi K; Mutaguchi K; Yamashita S
    Drug Metab Pharmacokinet; 2016 Dec; 31(6):405-410. PubMed ID: 27876352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of N-hexane inhalation on the enantioselective pharmacokinetics and metabolism of verapamil in rats.
    Mateus FH; Lepera JS; Marques MP; Boralli VB; Lanchote VL
    Chirality; 2010 Jan; 22(1):29-34. PubMed ID: 19229957
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacokinetics and first-pass elimination of metoprolol in rats: contribution of intestinal first-pass extraction to low bioavailability of metoprolol.
    Yoon IS; Choi MK; Kim JS; Shim CK; Chung SJ; Kim DD
    Xenobiotica; 2011 Mar; 41(3):243-51. PubMed ID: 21128757
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stereoselective first-pass metabolism of verapamil in the small intestine and liver in rats.
    Hanada K; Ikemi Y; Kukita K; Mihara K; Ogata H
    Drug Metab Dispos; 2008 Oct; 36(10):2037-42. PubMed ID: 18617604
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.
    Lau YY; Okochi H; Huang Y; Benet LZ
    Drug Metab Dispos; 2006 Jul; 34(7):1175-81. PubMed ID: 16624870
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Application of semisimultaneous midazolam administration for hepatic and intestinal cytochrome P450 3A phenotyping.
    Lee JI; Chaves-Gnecco D; Amico JA; Kroboth PD; Wilson JW; Frye RF
    Clin Pharmacol Ther; 2002 Dec; 72(6):718-28. PubMed ID: 12496753
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacokinetics of the enantiomers of verapamil in the dog.
    Bai SA; Lankford SM; Johnson LM
    Chirality; 1993; 5(6):436-42. PubMed ID: 8398603
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.