BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

734 related articles for article (PubMed ID: 23010360)

  • 1. A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias.
    Belardinelli L; Liu G; Smith-Maxwell C; Wang WQ; El-Bizri N; Hirakawa R; Karpinski S; Li CH; Hu L; Li XJ; Crumb W; Wu L; Koltun D; Zablocki J; Yao L; Dhalla AK; Rajamani S; Shryock JC
    J Pharmacol Exp Ther; 2013 Jan; 344(1):23-32. PubMed ID: 23010360
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective inhibition of physiological late Na
    El-Bizri N; Li CH; Liu GX; Rajamani S; Belardinelli L
    Am J Physiol Heart Circ Physiol; 2018 Feb; 314(2):H236-H245. PubMed ID: 28971840
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Late I
    Hwang J; Kim TY; Terentyev D; Zhong M; Kabakov AY; Bronk P; Arunachalam K; Belardinelli L; Rajamani S; Kunitomo Y; Pfeiffer Z; Lu Y; Peng X; Odening KE; Qu Z; Karma A; Koren G; Choi BR
    Circ Arrhythm Electrophysiol; 2020 Aug; 13(8):e006875. PubMed ID: 32628505
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts--role of late sodium current and intracellular ion accumulation.
    Sossalla S; Wagner S; Rasenack EC; Ruff H; Weber SL; Schöndube FA; Tirilomis T; Tenderich G; Hasenfuss G; Belardinelli L; Maier LS
    J Mol Cell Cardiol; 2008 Jul; 45(1):32-43. PubMed ID: 18439620
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sophocarpine attenuates the Na(+)-dependent Ca2(+) overload induced by Anemonia sulcata toxin-increased late sodium current in rabbit ventricular myocytes.
    Zhang S; Ma JH; Zhang PH; Luo AT; Ren ZQ; Kong LH
    J Cardiovasc Pharmacol; 2012 Oct; 60(4):357-66. PubMed ID: 23064241
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An increase in late sodium current potentiates the proarrhythmic activities of low-risk QT-prolonging drugs in female rabbit hearts.
    Wu L; Shryock JC; Song Y; Belardinelli L
    J Pharmacol Exp Ther; 2006 Feb; 316(2):718-26. PubMed ID: 16234410
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes.
    Song Y; Shryock JC; Belardinelli L
    Am J Physiol Heart Circ Physiol; 2008 May; 294(5):H2031-9. PubMed ID: 18310511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.
    Portero V; Casini S; Hoekstra M; Verkerk AO; Mengarelli I; Belardinelli L; Rajamani S; Wilde AAM; Bezzina CR; Veldkamp MW; Remme CA
    Cardiovasc Res; 2017 Jun; 113(7):829-838. PubMed ID: 28430892
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RSD1235 blocks late INa and suppresses early afterdepolarizations and torsades de pointes induced by class III agents.
    Orth PM; Hesketh JC; Mak CK; Yang Y; Lin S; Beatch GN; Ezrin AM; Fedida D
    Cardiovasc Res; 2006 Jun; 70(3):486-96. PubMed ID: 16545351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reduction of repolarization reserve unmasks the proarrhythmic role of endogenous late Na(+) current in the heart.
    Wu L; Rajamani S; Li H; January CT; Shryock JC; Belardinelli L
    Am J Physiol Heart Circ Physiol; 2009 Sep; 297(3):H1048-57. PubMed ID: 19592609
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.
    Bossu A; Houtman MJC; Meijborg VMF; Varkevisser R; Beekman HDM; Dunnink A; de Bakker JMT; Mollova N; Rajamani S; Belardinelli L; van der Heyden MAG; Vos MA
    Br J Pharmacol; 2018 Jun; 175(12):2470-2482. PubMed ID: 29582428
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of the Inhibition of Late Sodium Current by GS967 on Stretch-Induced Changes in Cardiac Electrophysiology.
    Del Canto I; Santamaría L; Genovés P; Such-Miquel L; Arias-Mutis O; Zarzoso M; Soler C; Parra G; Tormos Á; Alberola A; Such L; Chorro FJ
    Cardiovasc Drugs Ther; 2018 Oct; 32(5):413-425. PubMed ID: 30173392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome.
    Wu L; Shryock JC; Song Y; Li Y; Antzelevitch C; Belardinelli L
    J Pharmacol Exp Ther; 2004 Aug; 310(2):599-605. PubMed ID: 15031300
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.
    Wu L; Ma J; Li H; Wang C; Grandi E; Zhang P; Luo A; Bers DM; Shryock JC; Belardinelli L
    Circulation; 2011 Apr; 123(16):1713-20. PubMed ID: 21482963
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes.
    Song Y; Shryock JC; Wu L; Belardinelli L
    J Cardiovasc Pharmacol; 2004 Aug; 44(2):192-9. PubMed ID: 15243300
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ATX-II-induced pulmonary vein arrhythmogenesis related to atrial fibrillation and long QT syndrome.
    Lu YY; Cheng CC; Chen YC; Chen SA; Chen YJ
    Eur J Clin Invest; 2012 Aug; 42(8):823-31. PubMed ID: 22339387
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine.
    Sicouri S; Timothy KW; Zygmunt AC; Glass A; Goodrow RJ; Belardinelli L; Antzelevitch C
    Heart Rhythm; 2007 May; 4(5):638-47. PubMed ID: 17467634
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ranolazine antagonizes the effects of increased late sodium current on intracellular calcium cycling in rat isolated intact heart.
    Wasserstrom JA; Sharma R; O'Toole MJ; Zheng J; Kelly JE; Shryock J; Belardinelli L; Aistrup GL
    J Pharmacol Exp Ther; 2009 Nov; 331(2):382-91. PubMed ID: 19675298
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction.
    Song Y; Shryock JC; Wagner S; Maier LS; Belardinelli L
    J Pharmacol Exp Ther; 2006 Jul; 318(1):214-22. PubMed ID: 16565163
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sinus node dysfunction in ATX-II-induced in-vitro murine model of long QT3 syndrome and rescue effect of ranolazine.
    Wu J; Cheng L; Lammers WJ; Wu L; Wang X; Shryock JC; Belardinelli L; Lei M
    Prog Biophys Mol Biol; 2008; 98(2-3):198-207. PubMed ID: 19351514
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.