454 related articles for article (PubMed ID: 23011794)
1. Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum.
Malmquist NA; Moss TA; Mecheri S; Scherf A; Fuchter MJ
Proc Natl Acad Sci U S A; 2012 Oct; 109(41):16708-13. PubMed ID: 23011794
[TBL] [Abstract][Full Text] [Related]
2. Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.
Malmquist NA; Sundriyal S; Caron J; Chen P; Witkowski B; Menard D; Suwanarusk R; Renia L; Nosten F; Jiménez-Díaz MB; Angulo-Barturen I; Santos Martínez M; Ferrer S; Sanz LM; Gamo FJ; Wittlin S; Duffy S; Avery VM; Ruecker A; Delves MJ; Sinden RE; Fuchter MJ; Scherf A
Antimicrob Agents Chemother; 2015 Feb; 59(2):950-9. PubMed ID: 25421480
[TBL] [Abstract][Full Text] [Related]
3. The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during
Ngwa CJ; Kiesow MJ; Orchard LM; Farrukh A; Llinás M; Pradel G
Int J Mol Sci; 2019 Oct; 20(20):. PubMed ID: 31615031
[TBL] [Abstract][Full Text] [Related]
4. Antimalarial efficacy of Pongamia pinnata (L) Pierre against Plasmodium falciparum (3D7 strain) and Plasmodium berghei (ANKA).
Satish PVV; Sunita K
BMC Complement Altern Med; 2017 Sep; 17(1):458. PubMed ID: 28893216
[TBL] [Abstract][Full Text] [Related]
5. IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo.
Park KE; Johnson CM; Cabot RA
Reprod Fertil Dev; 2012; 24(6):813-21. PubMed ID: 22781932
[TBL] [Abstract][Full Text] [Related]
6. Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds.
Sundriyal S; Malmquist NA; Caron J; Blundell S; Liu F; Chen X; Srimongkolpithak N; Jin J; Charman SA; Scherf A; Fuchter MJ
ChemMedChem; 2014 Oct; 9(10):2360-2373. PubMed ID: 25044750
[TBL] [Abstract][Full Text] [Related]
7. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
Kubicek S; O'Sullivan RJ; August EM; Hickey ER; Zhang Q; Teodoro ML; Rea S; Mechtler K; Kowalski JA; Homon CA; Kelly TA; Jenuwein T
Mol Cell; 2007 Feb; 25(3):473-81. PubMed ID: 17289593
[TBL] [Abstract][Full Text] [Related]
8. Beneficial effects of diazepin-quinazolin-amine derivative (BIX-01294) on preimplantation development and molecular characteristics of cloned mouse embryos.
Huang Y; Jiang X; Yu M; Huang R; Yao J; Li M; Zheng F; Yang X
Reprod Fertil Dev; 2017 Jun; 29(6):1260-1269. PubMed ID: 27477633
[TBL] [Abstract][Full Text] [Related]
9. The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites.
Delves M; Plouffe D; Scheurer C; Meister S; Wittlin S; Winzeler EA; Sinden RE; Leroy D
PLoS Med; 2012 Feb; 9(2):e1001169. PubMed ID: 22363211
[TBL] [Abstract][Full Text] [Related]
10. Histone lysine methyltransferases and demethylases in Plasmodium falciparum.
Cui L; Fan Q; Cui L; Miao J
Int J Parasitol; 2008 Aug; 38(10):1083-97. PubMed ID: 18299133
[TBL] [Abstract][Full Text] [Related]
11. Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target.
Singh J; Vijay S; Mansuri R; Rawal R; Kadian K; Sahoo GC; Kumar M; Sharma A
PLoS One; 2019; 14(8):e0221032. PubMed ID: 31437171
[TBL] [Abstract][Full Text] [Related]
12. Fast-Acting Small Molecules Targeting Malarial Aspartyl Proteases, Plasmepsins, Inhibit Malaria Infection at Multiple Life Stages.
Singh S; Rajendran V; He J; Singh AK; Achieng AO; Vandana ; Pant A; Nasamu AS; Pandit M; Singh J; Quadiri A; Gupta N; Poonam ; Ghosh PC; Singh BK; Narayanan L; Kempaiah P; Chandra R; Dunn BM; Pandey KC; Goldberg DE; Singh AP; Rathi B
ACS Infect Dis; 2019 Feb; 5(2):184-198. PubMed ID: 30554511
[TBL] [Abstract][Full Text] [Related]
13. Characterising the effect of antimalarial drugs on the maturation and clearance of murine blood-stage Plasmodium parasites in vivo.
Khoury DS; Cromer D; Elliott T; Soon MSF; Thomas BS; James KR; Best SE; Aogo RA; Engel JA; Gartlan KH; Akter J; Sebina I; Haque A; Davenport MP
Int J Parasitol; 2017 Dec; 47(14):913-922. PubMed ID: 28864033
[TBL] [Abstract][Full Text] [Related]
14. Eugenol disrupts Plasmodium falciparum intracellular development during the erythrocytic cycle and protects against cerebral malaria.
Pontes KAO; Silva LS; Santos EC; Pinheiro AS; Teixeira DE; Peruchetti DB; Silva-Aguiar RP; Wendt CHC; Miranda KR; Coelho-de-Souza AN; Leal-Cardoso JH; Caruso-Neves C; Pinheiro AAS
Biochim Biophys Acta Gen Subj; 2021 Mar; 1865(3):129813. PubMed ID: 33321150
[TBL] [Abstract][Full Text] [Related]
15. Novel inhibitor of Plasmodium histone deacetylase that cures P. berghei-infected mice.
Agbor-Enoh S; Seudieu C; Davidson E; Dritschilo A; Jung M
Antimicrob Agents Chemother; 2009 May; 53(5):1727-34. PubMed ID: 19223622
[TBL] [Abstract][Full Text] [Related]
16. Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Biagini GA; Fisher N; Shone AE; Mubaraki MA; Srivastava A; Hill A; Antoine T; Warman AJ; Davies J; Pidathala C; Amewu RK; Leung SC; Sharma R; Gibbons P; Hong DW; Pacorel B; Lawrenson AS; Charoensutthivarakul S; Taylor L; Berger O; Mbekeani A; Stocks PA; Nixon GL; Chadwick J; Hemingway J; Delves MJ; Sinden RE; Zeeman AM; Kocken CH; Berry NG; O'Neill PM; Ward SA
Proc Natl Acad Sci U S A; 2012 May; 109(21):8298-303. PubMed ID: 22566611
[TBL] [Abstract][Full Text] [Related]
17. Identification of novel quinazoline derivatives as potent antiplasmodial agents.
Bouchut A; Rotili D; Pierrot C; Valente S; Lafitte S; Schultz J; Hoglund U; Mazzone R; Lucidi A; Fabrizi G; Pechalrieu D; Arimondo PB; Skinner-Adams TS; Chua MJ; Andrews KT; Mai A; Khalife J
Eur J Med Chem; 2019 Jan; 161():277-291. PubMed ID: 30366254
[TBL] [Abstract][Full Text] [Related]
18. Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites.
Chen PB; Ding S; Zanghì G; Soulard V; DiMaggio PA; Fuchter MJ; Mecheri S; Mazier D; Scherf A; Malmquist NA
Sci Rep; 2016 Feb; 6():21802. PubMed ID: 26902486
[TBL] [Abstract][Full Text] [Related]
19. Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model.
Kumar P; Achieng AO; Rajendran V; Ghosh PC; Singh BK; Rawat M; Perkins DJ; Kempaiah P; Rathi B
Sci Rep; 2017 Jul; 7(1):6724. PubMed ID: 28751747
[TBL] [Abstract][Full Text] [Related]
20. Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
Chang Y; Zhang X; Horton JR; Upadhyay AK; Spannhoff A; Liu J; Snyder JP; Bedford MT; Cheng X
Nat Struct Mol Biol; 2009 Mar; 16(3):312-7. PubMed ID: 19219047
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
