224 related articles for article (PubMed ID: 23011796)
1. Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region.
Stephenson NL; Avis JM
Proc Natl Acad Sci U S A; 2012 Oct; 109(41):E2757-65. PubMed ID: 23011796
[TBL] [Abstract][Full Text] [Related]
2. Mutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability.
Stephenson NL; Avis JM
FEBS Open Bio; 2015; 5():625-33. PubMed ID: 26288744
[TBL] [Abstract][Full Text] [Related]
3. Force-induced unfolding simulations of the human Notch1 negative regulatory region: possible roles of the heterodimerization domain in mechanosensing.
Chen J; Zolkiewska A
PLoS One; 2011; 6(7):e22837. PubMed ID: 21829530
[TBL] [Abstract][Full Text] [Related]
4. Human NOTCH2 Is Resistant to Ligand-independent Activation by Metalloprotease Adam17.
Habets RA; Groot AJ; Yahyanejad S; Tiyanont K; Blacklow SC; Vooijs M
J Biol Chem; 2015 Jun; 290(23):14705-16. PubMed ID: 25918160
[TBL] [Abstract][Full Text] [Related]
5. Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2.
Gordon WR; Vardar-Ulu D; L'Heureux S; Ashworth T; Malecki MJ; Sanchez-Irizarry C; McArthur DG; Histen G; Mitchell JL; Aster JC; Blacklow SC
PLoS One; 2009 Aug; 4(8):e6613. PubMed ID: 19701457
[TBL] [Abstract][Full Text] [Related]
6. Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL.
Gordon WR; Roy M; Vardar-Ulu D; Garfinkel M; Mansour MR; Aster JC; Blacklow SC
Blood; 2009 Apr; 113(18):4381-90. PubMed ID: 19075186
[TBL] [Abstract][Full Text] [Related]
7. Single molecule studies of force-induced S2 site exposure in the mammalian Notch negative regulatory domain.
Ploscariu N; Kuczera K; Malek KE; Wawrzyniuk M; Dey A; Szoszkiewicz R
J Phys Chem B; 2014 May; 118(18):4761-70. PubMed ID: 24735465
[TBL] [Abstract][Full Text] [Related]
8. Insights into Notch3 activation and inhibition mediated by antibodies directed against its negative regulatory region.
Tiyanont K; Wales TE; Siebel CW; Engen JR; Blacklow SC
J Mol Biol; 2013 Sep; 425(17):3192-204. PubMed ID: 23747483
[TBL] [Abstract][Full Text] [Related]
9. Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.
Gordon WR; Zimmerman B; He L; Miles LJ; Huang J; Tiyanont K; McArthur DG; Aster JC; Perrimon N; Loparo JJ; Blacklow SC
Dev Cell; 2015 Jun; 33(6):729-36. PubMed ID: 26051539
[TBL] [Abstract][Full Text] [Related]
10. Structural basis for autoinhibition of Notch.
Gordon WR; Vardar-Ulu D; Histen G; Sanchez-Irizarry C; Aster JC; Blacklow SC
Nat Struct Mol Biol; 2007 Apr; 14(4):295-300. PubMed ID: 17401372
[TBL] [Abstract][Full Text] [Related]
11. Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.
Bozkulak EC; Weinmaster G
Mol Cell Biol; 2009 Nov; 29(21):5679-95. PubMed ID: 19704010
[TBL] [Abstract][Full Text] [Related]
12. Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins.
Groot AJ; Habets R; Yahyanejad S; Hodin CM; Reiss K; Saftig P; Theys J; Vooijs M
Mol Cell Biol; 2014 Aug; 34(15):2822-32. PubMed ID: 24842903
[TBL] [Abstract][Full Text] [Related]
13. Evidence for increased exposure of the Notch1 metalloprotease cleavage site upon conversion to an activated conformation.
Tiyanont K; Wales TE; Aste-Amezaga M; Aster JC; Engen JR; Blacklow SC
Structure; 2011 Apr; 19(4):546-54. PubMed ID: 21481777
[TBL] [Abstract][Full Text] [Related]
14. Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region.
Xu X; Choi SH; Hu T; Tiyanont K; Habets R; Groot AJ; Vooijs M; Aster JC; Chopra R; Fryer C; Blacklow SC
Structure; 2015 Jul; 23(7):1227-35. PubMed ID: 26051713
[TBL] [Abstract][Full Text] [Related]
15. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments.
LaVoie MJ; Selkoe DJ
J Biol Chem; 2003 Sep; 278(36):34427-37. PubMed ID: 12826675
[TBL] [Abstract][Full Text] [Related]
16. The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity.
Boldt HB; Kjaer-Sorensen K; Overgaard MT; Weyer K; Poulsen CB; Sottrup-Jensen L; Conover CA; Giudice LC; Oxvig C
J Biol Chem; 2004 Sep; 279(37):38525-31. PubMed ID: 15262980
[TBL] [Abstract][Full Text] [Related]
17. Evolutionary plasticity in the requirement for force exerted by ligand endocytosis to activate C. elegans Notch proteins.
Langridge PD; Garcia Diaz A; Chan JY; Greenwald I; Struhl G
Curr Biol; 2022 May; 32(10):2263-2271.e6. PubMed ID: 35349791
[TBL] [Abstract][Full Text] [Related]
18. The Molecular Mechanism of Notch Activation.
Lovendahl KN; Blacklow SC; Gordon WR
Adv Exp Med Biol; 2018; 1066():47-58. PubMed ID: 30030821
[TBL] [Abstract][Full Text] [Related]
19. ADAM proteases: ligand processing and modulation of the Notch pathway.
Zolkiewska A
Cell Mol Life Sci; 2008 Jul; 65(13):2056-68. PubMed ID: 18344021
[TBL] [Abstract][Full Text] [Related]
20. Therapeutic antibody targeting of individual Notch receptors.
Wu Y; Cain-Hom C; Choy L; Hagenbeek TJ; de Leon GP; Chen Y; Finkle D; Venook R; Wu X; Ridgway J; Schahin-Reed D; Dow GJ; Shelton A; Stawicki S; Watts RJ; Zhang J; Choy R; Howard P; Kadyk L; Yan M; Zha J; Callahan CA; Hymowitz SG; Siebel CW
Nature; 2010 Apr; 464(7291):1052-7. PubMed ID: 20393564
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
