These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 23013248)

  • 1. Comparative NMR-based metabonomic investigation of the metabolic phenotype associated with tienilic acid and tienilic acid isomer.
    Coen M; Rademacher PM; Zou W; Scott M; Ganey PE; Roth R; Nelson SD
    Chem Res Toxicol; 2012 Nov; 25(11):2412-22. PubMed ID: 23013248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Opposite behaviors of reactive metabolites of tienilic acid and its isomer toward liver proteins: use of specific anti-tienilic acid-protein adduct antibodies and the possible relationship with different hepatotoxic effects of the two compounds.
    Bonierbale E; Valadon P; Pons C; Desfosses B; Dansette PM; Mansuy D
    Chem Res Toxicol; 1999 Mar; 12(3):286-96. PubMed ID: 10077492
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential oxidation of two thiophene-containing regioisomers to reactive metabolites by cytochrome P450 2C9.
    Rademacher PM; Woods CM; Huang Q; Szklarz GD; Nelson SD
    Chem Res Toxicol; 2012 Apr; 25(4):895-903. PubMed ID: 22329513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes.
    Dansette PM; Amar C; Smith C; Pons C; Mansuy D
    Biochem Pharmacol; 1990 Mar; 39(5):911-8. PubMed ID: 2310416
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Involvement of cytochrome P450-mediated metabolism in tienilic acid hepatotoxicity in rats.
    Nishiya T; Kato M; Suzuki T; Maru C; Kataoka H; Hattori C; Mori K; Jindo T; Tanaka Y; Manabe S
    Toxicol Lett; 2008 Dec; 183(1-3):81-9. PubMed ID: 18992796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hydroxylation and formation of electrophilic metabolites of tienilic acid and its isomer by human liver microsomes. Catalysis by a cytochrome P450 IIC different from that responsible for mephenytoin hydroxylation.
    Dansette PM; Amar C; Valadon P; Pons C; Beaune PH; Mansuy D
    Biochem Pharmacol; 1991 Feb; 41(4):553-60. PubMed ID: 1997003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular structure and hepatotoxicity: compared data about two closely related thiophene compounds.
    Mansuy D
    J Hepatol; 1997; 26 Suppl 2():22-5. PubMed ID: 9204406
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The crucial protective role of glutathione against tienilic acid hepatotoxicity in rats.
    Nishiya T; Mori K; Hattori C; Kai K; Kataoka H; Masubuchi N; Jindo T; Manabe S
    Toxicol Appl Pharmacol; 2008 Oct; 232(2):280-91. PubMed ID: 18708081
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer.
    Kyriakides M; Maitre L; Stamper BD; Mohar I; Kavanagh TJ; Foster J; Wilson ID; Holmes E; Nelson SD; Coen M
    Arch Toxicol; 2016 Dec; 90(12):3073-3085. PubMed ID: 26746206
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human-liver cytochromes P-450 expressed in yeast as tools for reactive-metabolite formation studies. Oxidative activation of tienilic acid by cytochromes P-450 2C9 and 2C10.
    Lopez Garcia MP; Dansette PM; Valadon P; Amar C; Beaune PH; Guengerich FP; Mansuy D
    Eur J Biochem; 1993 Apr; 213(1):223-32. PubMed ID: 8477697
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity.
    Coen M; Goldfain-Blanc F; Rolland-Valognes G; Walther B; Robertson DG; Holmes E; Lindon JC; Nicholson JK
    J Proteome Res; 2012 Apr; 11(4):2427-40. PubMed ID: 22384821
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic hydroxylation of the thiophene ring: isolation of 5-hydroxy-tienilic acid as the major urinary metabolite of tienilic acid in man and rat.
    Mansuy D; Dansette PM; Foures C; Jaouen M; Moinet G; Bayer N
    Biochem Pharmacol; 1984 May; 33(9):1429-35. PubMed ID: 6732860
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid.
    López-Garcia MP; Dansette PM; Mansuy D
    Biochemistry; 1994 Jan; 33(1):166-75. PubMed ID: 8286335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Capillary ultra performance liquid chromatography-tandem mass spectrometry analysis of tienilic acid metabolites in urine following intravenous administration to the rat.
    King AM; Grant I; Rainville PD; Isaac G; Coen M; Wilson ID; Plumb RS
    J Chromatogr B Analyt Technol Biomed Life Sci; 2018 Jun; 1087-1088():142-148. PubMed ID: 29738964
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of protein targets of reactive metabolites of tienilic acid in human hepatocytes.
    Koen YM; Sarma D; Williams TD; Galeva NA; Obach RS; Hanzlik RP
    Chem Res Toxicol; 2012 May; 25(5):1145-54. PubMed ID: 22462724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabonomics study of urine from Sprague-Dawley rats exposed to Huang-yao-zi using (1)H NMR spectroscopy.
    Liu Y; Huang R; Liu L; Peng J; Xiao B; Yang J; Miao Z; Huang H
    J Pharm Biomed Anal; 2010 May; 52(1):136-41. PubMed ID: 20061116
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacokinetic and pharmacodynamic studies of tienilic acid in healthy volunteers.
    Kerremans AL; Gribnau FW; Tan Y; van Ginneken CA
    Eur J Clin Pharmacol; 1982; 22(6):515-21. PubMed ID: 7128663
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach.
    Waters NJ; Holmes E; Williams A; Waterfield CJ; Farrant RD; Nicholson JK
    Chem Res Toxicol; 2001 Oct; 14(10):1401-12. PubMed ID: 11599932
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    Huo T; Fang Y; Zhao L; Xiong Z; Zhang Y; Wang Y; Feng C; Yuan M; Wang S; Chen M; Jiang H
    J Ethnopharmacol; 2016 Nov; 192():1-9. PubMed ID: 27377338
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 6.