169 related articles for article (PubMed ID: 23022675)
1. RNA interference targeting E637K mutation rescues hERG channel currents and restores its kinetic properties.
Lu X; Yang X; Huang X; Huang C; Sun HH; Jin L; Xu W; Mao H; Guo J; Zhou J; Lian J
Heart Rhythm; 2013 Jan; 10(1):128-36. PubMed ID: 23022675
[TBL] [Abstract][Full Text] [Related]
2. Pharmacologic Approach to Defective Protein Trafficking in the E637K-hERG Mutant with PD-118057 and Thapsigargin.
Mao H; Lu X; Karush JM; Huang X; Yang X; Ba Y; Wang Y; Liu N; Zhou J; Lian J
PLoS One; 2013; 8(6):e65481. PubMed ID: 23840331
[TBL] [Abstract][Full Text] [Related]
3. Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome.
Hayashi K; Shimizu M; Ino H; Yamaguchi M; Mabuchi H; Hoshi N; Higashida H
Cardiovasc Res; 2002 Apr; 54(1):67-76. PubMed ID: 12062363
[TBL] [Abstract][Full Text] [Related]
4. HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
Yang HT; Sun CF; Cui CC; Xue XL; Zhang AF; Li HB; Wang DQ; Shu J
Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):822-7. PubMed ID: 19215240
[TBL] [Abstract][Full Text] [Related]
5. Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2.
Aidery P; Kisselbach J; Gaspar H; Baldea I; Schweizer PA; Becker R; Katus HA; Thomas D
Biochem Biophys Res Commun; 2012 Feb; 418(4):830-5. PubMed ID: 22314138
[TBL] [Abstract][Full Text] [Related]
6. HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.
Paulussen AD; Raes A; Jongbloed RJ; Gilissen RA; Wilde AA; Snyders DJ; Smeets HJ; Aerssens J
Cardiovasc Res; 2005 Aug; 67(3):467-75. PubMed ID: 15958262
[TBL] [Abstract][Full Text] [Related]
7. The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells.
Huo J; Zhang Y; Huang N; Liu P; Huang C; Guo X; Jiang W; Zhou N; Grace A; Huang CL; Ma A
Pflugers Arch; 2008 Aug; 456(5):917-28. PubMed ID: 18386051
[TBL] [Abstract][Full Text] [Related]
8. Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum.
Wang Y; Huang X; Zhou J; Yang X; Li D; Mao H; Sun HH; Liu N; Lian J
PLoS One; 2012; 7(1):e29885. PubMed ID: 22242185
[TBL] [Abstract][Full Text] [Related]
9. Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).
Kang Y; Guo J; Yang T; Li W; Zhang S
Biochem J; 2015 Nov; 472(1):71-82. PubMed ID: 26363003
[TBL] [Abstract][Full Text] [Related]
10. Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.
Lian J; Huang N; Zhou J; Ge S; Huang X; Huo J; Liu L; Xu W; Zhang S; Yang X; Zhou J; Huang C
Can J Cardiol; 2010 Oct; 26(8):417-22. PubMed ID: 20931094
[TBL] [Abstract][Full Text] [Related]
11. Extracellular K+ is a prerequisite for the function and plasma membrane stability of HERG channels.
Massaeli H; Guo J; Xu J; Zhang S
Circ Res; 2010 Apr; 106(6):1072-82. PubMed ID: 20133899
[TBL] [Abstract][Full Text] [Related]
12. HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs.
Bai YL; Liu HB; Sun B; Zhang Y; Li Q; Hu CW; Zhu JX; Gong DM; Teng X; Zhang Q; Yang BF; Dong DL
J Mol Cell Cardiol; 2011 Nov; 51(5):876-80. PubMed ID: 21820442
[TBL] [Abstract][Full Text] [Related]
13. [The mechanistic rote of KCNH2 gene L413P and L559H mutations in long QT syndrome].
Li CL; Hu DY; Liu WL; Qi SY; Wang HT; Li L; Gong QM; Zhou ZF
Zhonghua Nei Ke Za Zhi; 2007 Oct; 46(10):838-41. PubMed ID: 18218237
[TBL] [Abstract][Full Text] [Related]
14. Partially dominant mutant channel defect corresponding with intermediate LQT2 phenotype.
Krishnan Y; Zheng R; Walsh C; Tang Y; McDonald TV
Pacing Clin Electrophysiol; 2012 Jan; 35(1):3-16. PubMed ID: 21951015
[TBL] [Abstract][Full Text] [Related]
15. Aminoglycoside antibiotics restore functional expression of truncated HERG channels produced by nonsense mutations.
Yao Y; Teng S; Li N; Zhang Y; Boyden PA; Pu J
Heart Rhythm; 2009 Apr; 6(4):553-60. PubMed ID: 19324319
[TBL] [Abstract][Full Text] [Related]
16. F463L increases the potential of dofetilide on human ether-a-go-go-related gene (hERG) channels.
Cheng G; Wu J; Han W; Sun C
Microsc Res Tech; 2018 Jun; 81(6):663-668. PubMed ID: 29573040
[TBL] [Abstract][Full Text] [Related]
17. Identification and functional characterization of the human ether-a-go-go-related gene Q738X mutant associated with hereditary long QT syndrome type 2.
Han SN; Yang SH; Zhang Y; Sun XY; Duan YY; Hu XJ; Fan TL; Huang CZ; Yang G; Zhang Z; Zhang L
Int J Mol Med; 2014 Sep; 34(3):810-5. PubMed ID: 24993425
[TBL] [Abstract][Full Text] [Related]
18. Functional effects of a missense mutation in HERG associated with type 2 long QT syndrome.
Amorós I; Jiménez-Jáimez J; Tercedor L; Barana A; Gómez R; de la Fuente MG; Dolz-Gaitón P; Alvarez M; Martínez-Espín E; Lorente JA; Melgares R; Tamargo J; Delpón E; Caballero R
Heart Rhythm; 2011 Mar; 8(3):463-70. PubMed ID: 21109023
[TBL] [Abstract][Full Text] [Related]
19. Molecular determinants of cocaine block of human ether-á-go-go-related gene potassium channels.
Guo J; Gang H; Zhang S
J Pharmacol Exp Ther; 2006 May; 317(2):865-74. PubMed ID: 16397089
[TBL] [Abstract][Full Text] [Related]
20. Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes.
Guo J; Massaeli H; Li W; Xu J; Luo T; Shaw J; Kirshenbaum LA; Zhang S
J Pharmacol Exp Ther; 2007 Jun; 321(3):911-20. PubMed ID: 17377062
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
