BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 23026564)

  • 1. The transition state analog inhibitor of Purine Nucleoside Phosphorylase (PNP) Immucillin-H arrests bone loss in rat periodontal disease models.
    Deves C; de Assunção TM; Ducati RG; Campos MM; Basso LA; Santos DS; Batista EL
    Bone; 2013 Jan; 52(1):167-75. PubMed ID: 23026564
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for inhibition of human PNP by immucillin-H.
    Filgueira de Azevedo W; Canduri F; Marangoni dos Santos D; Pereira JH; Dias MV; Silva RG; Mendes MA; Basso LA; Palma MS; Santos DS
    Biochem Biophys Res Commun; 2003 Oct; 309(4):917-22. PubMed ID: 13679061
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.
    Deng H; Lewandowicz A; Cahill SM; Furneaux RH; Tyler PC; Girvin ME; Callender RH; Schramm VL
    Biochemistry; 2004 Feb; 43(7):1980-7. PubMed ID: 14967038
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase.
    Kicska GA; Tyler PC; Evans GB; Furneaux RH; Schramm VL; Kim K
    J Biol Chem; 2002 Feb; 277(5):3226-31. PubMed ID: 11706018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
    Miles RW; Tyler PC; Furneaux RH; Bagdassarian CK; Schramm VL
    Biochemistry; 1998 Jun; 37(24):8615-21. PubMed ID: 9628722
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes.
    Kicska GA; Long L; Hörig H; Fairchild C; Tyler PC; Furneaux RH; Schramm VL; Kaufman HL
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4593-8. PubMed ID: 11287638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New catalytic mechanism for human purine nucleoside phosphorylase.
    Canduri F; Fadel V; Basso LA; Palma MS; Santos DS; de Azevedo WF
    Biochem Biophys Res Commun; 2005 Feb; 327(3):646-9. PubMed ID: 15649395
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Forodesine (BCX-1777, Immucillin H)--a new purine nucleoside analogue: mechanism of action and potential clinical application.
    Korycka A; Błoński JZ; Robak T
    Mini Rev Med Chem; 2007 Sep; 7(9):976-83. PubMed ID: 17897085
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts.
    Basso LA; Santos DS; Shi W; Furneaux RH; Tyler PC; Schramm VL; Blanchard JS
    Biochemistry; 2001 Jul; 40(28):8196-203. PubMed ID: 11444965
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Four generations of transition-state analogues for human purine nucleoside phosphorylase.
    Ho MC; Shi W; Rinaldo-Matthis A; Tyler PC; Evans GB; Clinch K; Almo SC; Schramm VL
    Proc Natl Acad Sci U S A; 2010 Mar; 107(11):4805-12. PubMed ID: 20212140
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.
    Evans GB; Furneaux RH; Lewandowicz A; Schramm VL; Tyler PC
    J Med Chem; 2003 Jul; 46(15):3412-23. PubMed ID: 12852771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Immucillin-H binding to purine nucleoside phosphorylase reduces dynamic solvent exchange.
    Wang F; Miles RW; Kicska G; Nieves E; Schramm VL; Angeletti RH
    Protein Sci; 2000 Sep; 9(9):1660-8. PubMed ID: 11045613
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent.
    Bantia S; Miller PJ; Parker CD; Ananth SL; Horn LL; Kilpatrick JM; Morris PE; Hutchison TL; Montgomery JA; Sandhu JS
    Int Immunopharmacol; 2001 Jun; 1(6):1199-210. PubMed ID: 11407314
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents.
    Schramm VL
    Biochim Biophys Acta; 2002 Jul; 1587(2-3):107-17. PubMed ID: 12084452
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: Preliminary in vitro studies with analogues of immucillin-G.
    Jacomelli G; Baldini E; Mugnaini C; Micheli V; Bernardini G; Santucci A
    J Inherit Metab Dis; 2019 Jan; 42(1):178-185. PubMed ID: 30740729
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of human PNP complexed with ligands.
    Canduri F; Silva RG; dos Santos DM; Palma MS; Basso LA; Santos DS; de Azevedo WF
    Acta Crystallogr D Biol Crystallogr; 2005 Jul; 61(Pt 7):856-62. PubMed ID: 15983407
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Purine nucleoside phosphorylase activity and expression are upregulated in sites affected by periodontal disease.
    Batista EL; Deves C; Ayub L; da Silva RG; Filho LC; Basso LA; Santos DS
    J Periodontal Res; 2010 Oct; 45(5):664-71. PubMed ID: 20572921
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transition states and inhibitors of the purine nucleoside phosphorylase family.
    Taylor Ringia EA; Schramm VL
    Curr Top Med Chem; 2005; 5(13):1237-58. PubMed ID: 16305529
    [TBL] [Abstract][Full Text] [Related]  

  • 19. L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
    Rinaldo-Matthis A; Murkin AS; Ramagopal UA; Clinch K; Mee SP; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
    J Am Chem Soc; 2008 Jan; 130(3):842-4. PubMed ID: 18154341
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine).
    Gandhi V; Kilpatrick JM; Plunkett W; Ayres M; Harman L; Du M; Bantia S; Davisson J; Wierda WG; Faderl S; Kantarjian H; Thomas D
    Blood; 2005 Dec; 106(13):4253-60. PubMed ID: 16131572
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.