BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

429 related articles for article (PubMed ID: 23029491)

  • 1. Limited phenotypic effects of selectively augmenting the SMN protein in the neurons of a mouse model of severe spinal muscular atrophy.
    Lee AJ; Awano T; Park GH; Monani UR
    PLoS One; 2012; 7(9):e46353. PubMed ID: 23029491
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene.
    Park GH; Maeno-Hikichi Y; Awano T; Landmesser LT; Monani UR
    J Neurosci; 2010 Sep; 30(36):12005-19. PubMed ID: 20826664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Motor neuronal repletion of the NMJ organizer, Agrin, modulates the severity of the spinal muscular atrophy disease phenotype in model mice.
    Kim JK; Caine C; Awano T; Herbst R; Monani UR
    Hum Mol Genet; 2017 Jul; 26(13):2377-2385. PubMed ID: 28379354
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Restoration of SMN to Emx-1 expressing cortical neurons is not sufficient to provide benefit to a severe mouse model of Spinal Muscular Atrophy.
    Taylor AS; Glascock JJ; Rose FF; Lutz C; Lorson CL
    Transgenic Res; 2013 Oct; 22(5):1029-36. PubMed ID: 23512182
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy.
    Deguise MO; De Repentigny Y; Tierney A; Beauvais A; Michaud J; Chehade L; Thabet M; Paul B; Reilly A; Gagnon S; Renaud JM; Kothary R
    EBioMedicine; 2020 May; 55():102750. PubMed ID: 32339936
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.
    Martinez TL; Kong L; Wang X; Osborne MA; Crowder ME; Van Meerbeke JP; Xu X; Davis C; Wooley J; Goldhamer DJ; Lutz CM; Rich MM; Sumner CJ
    J Neurosci; 2012 Jun; 32(25):8703-15. PubMed ID: 22723710
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.
    Bowerman M; Murray LM; Beauvais A; Pinheiro B; Kothary R
    Neuromuscul Disord; 2012 Mar; 22(3):263-76. PubMed ID: 22071333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Muscle-specific SMN reduction reveals motor neuron-independent disease in spinal muscular atrophy models.
    Kim JK; Jha NN; Feng Z; Faleiro MR; Chiriboga CA; Wei-Lapierre L; Dirksen RT; Ko CP; Monani UR
    J Clin Invest; 2020 Mar; 130(3):1271-1287. PubMed ID: 32039917
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction between alpha-COP and SMN ameliorates disease phenotype in a mouse model of spinal muscular atrophy.
    Custer SK; Astroski JW; Li HX; Androphy EJ
    Biochem Biophys Res Commun; 2019 Jun; 514(2):530-537. PubMed ID: 31060774
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Astrocytes influence the severity of spinal muscular atrophy.
    Rindt H; Feng Z; Mazzasette C; Glascock JJ; Valdivia D; Pyles N; Crawford TO; Swoboda KJ; Patitucci TN; Ebert AD; Sumner CJ; Ko CP; Lorson CL
    Hum Mol Genet; 2015 Jul; 24(14):4094-102. PubMed ID: 25911676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model.
    Hua Y; Sahashi K; Rigo F; Hung G; Horev G; Bennett CF; Krainer AR
    Nature; 2011 Oct; 478(7367):123-6. PubMed ID: 21979052
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses.
    Kim JK; Jha NN; Awano T; Caine C; Gollapalli K; Welby E; Kim SS; Fuentes-Moliz A; Wang X; Feng Z; Sera F; Takeda T; Homma S; Ko CP; Tabares L; Ebert AD; Rich MM; Monani UR
    Neuron; 2023 May; 111(9):1423-1439.e4. PubMed ID: 36863345
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypothermia improves disease manifestations in SMA mice via SMN augmentation.
    Tsai LK; Chen CL; Tsai YC; Ting CH; Chien YH; Lee NC; Hwu WL
    Hum Mol Genet; 2016 Feb; 25(4):631-41. PubMed ID: 26647309
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteomic assessment of a cell model of spinal muscular atrophy.
    Wu CY; Whye D; Glazewski L; Choe L; Kerr D; Lee KH; Mason RW; Wang W
    BMC Neurosci; 2011 Mar; 12():25. PubMed ID: 21385431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment.
    Sintusek P; Catapano F; Angkathunkayul N; Marrosu E; Parson SH; Morgan JE; Muntoni F; Zhou H
    PLoS One; 2016; 11(5):e0155032. PubMed ID: 27163330
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Zebrafish survival motor neuron mutants exhibit presynaptic neuromuscular junction defects.
    Boon KL; Xiao S; McWhorter ML; Donn T; Wolf-Saxon E; Bohnsack MT; Moens CB; Beattie CE
    Hum Mol Genet; 2009 Oct; 18(19):3615-25. PubMed ID: 19592581
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse.
    McGovern VL; Massoni-Laporte A; Wang X; Le TT; Le HT; Beattie CE; Rich MM; Burghes AH
    PLoS One; 2015; 10(7):e0132364. PubMed ID: 26134627
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy.
    Riessland M; Ackermann B; Förster A; Jakubik M; Hauke J; Garbes L; Fritzsche I; Mende Y; Blumcke I; Hahnen E; Wirth B
    Hum Mol Genet; 2010 Apr; 19(8):1492-506. PubMed ID: 20097677
    [TBL] [Abstract][Full Text] [Related]  

  • 19. At the "junction" of spinal muscular atrophy pathogenesis: the role of neuromuscular junction dysfunction in SMA disease progression.
    Goulet BB; Kothary R; Parks RJ
    Curr Mol Med; 2013 Aug; 13(7):1160-74. PubMed ID: 23514457
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AAV9-Mediated Expression of SMN Restricted to Neurons Does Not Rescue the Spinal Muscular Atrophy Phenotype in Mice.
    Besse A; Astord S; Marais T; Roda M; Giroux B; Lejeune FX; Relaix F; Smeriglio P; Barkats M; Biferi MG
    Mol Ther; 2020 Aug; 28(8):1887-1901. PubMed ID: 32470325
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.