BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

564 related articles for article (PubMed ID: 23033485)

  • 21. [HERG K+ channel, the target of anti-arrhythmias drugs].
    Guan FY; Yang SJ
    Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
    [TBL] [Abstract][Full Text] [Related]  

  • 22. F463L increases the potential of dofetilide on human ether-a-go-go-related gene (hERG) channels.
    Cheng G; Wu J; Han W; Sun C
    Microsc Res Tech; 2018 Jun; 81(6):663-668. PubMed ID: 29573040
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.
    Johannesen L; Vicente J; Mason JW; Sanabria C; Waite-Labott K; Hong M; Guo P; Lin J; Sørensen JS; Galeotti L; Florian J; Ugander M; Stockbridge N; Strauss DG
    Clin Pharmacol Ther; 2014 Nov; 96(5):549-58. PubMed ID: 25054430
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.
    Ficker E; Jarolimek W; Brown AM
    Mol Pharmacol; 2001 Dec; 60(6):1343-8. PubMed ID: 11723241
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Exploring chemical substructures essential for HERG k(+) channel blockade by synthesis and biological evaluation of dofetilide analogues.
    ; Guo D; Klaasse E; de Vries H; Brussee J; Nalos L; Rook MB; Vos MA; van der Heyden MA; Ijzerman AP
    ChemMedChem; 2009 Oct; 4(10):1722-32. PubMed ID: 19725081
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Iloperidone (Fanapt®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration.
    Vigneault P; Pilote S; Patoine D; Simard C; Drolet B
    Pharmacol Res; 2012 Jul; 66(1):60-5. PubMed ID: 22465688
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Correlation between human ether-a-go-go-related gene channel inhibition and action potential prolongation.
    Saxena P; Hortigon-Vinagre MP; Beyl S; Baburin I; Andranovits S; Iqbal SM; Costa A; IJzerman AP; Kügler P; Timin E; Smith GL; Hering S
    Br J Pharmacol; 2017 Sep; 174(18):3081-3093. PubMed ID: 28681507
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structural determinants of HERG channel block by clofilium and ibutilide.
    Perry M; de Groot MJ; Helliwell R; Leishman D; Tristani-Firouzi M; Sanguinetti MC; Mitcheson J
    Mol Pharmacol; 2004 Aug; 66(2):240-9. PubMed ID: 15266014
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Fluorescently labeled analogues of dofetilide as high-affinity fluorescence polarization ligands for the human ether-a-go-go-related gene (hERG) channel.
    Singleton DH; Boyd H; Steidl-Nichols JV; Deacon M; Groot MJ; Price D; Nettleton DO; Wallace NK; Troutman MD; Williams C; Boyd JG
    J Med Chem; 2007 Jun; 50(13):2931-41. PubMed ID: 17536794
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Interactions at human ether-à-go-go-related gene channels.
    Friemel A; Zünkler BJ
    Toxicol Sci; 2010 Apr; 114(2):346-55. PubMed ID: 20071423
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells.
    Jehle J; Ficker E; Wan X; Deschenes I; Kisselbach J; Wiedmann F; Staudacher I; Schmidt C; Schweizer PA; Becker R; Katus HA; Thomas D
    Br J Pharmacol; 2013 Mar; 168(5):1215-29. PubMed ID: 23061993
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.
    Park MH; Lee SH; Chu DH; Won KH; Choi BH; Choe H; Jo SH
    J Pharmacol Sci; 2013 Sep; 123(1):67-77. PubMed ID: 24005046
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Molecular determinants of HERG channel block.
    Kamiya K; Niwa R; Mitcheson JS; Sanguinetti MC
    Mol Pharmacol; 2006 May; 69(5):1709-16. PubMed ID: 16474003
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells.
    De Waard S; Montnach J; Ribeiro B; Nicolas S; Forest V; Charpentier F; Mangoni ME; Gaborit N; Ronjat M; Loussouarn G; Lemarchand P; De Waard M
    Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 32998413
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The calmodulin inhibitor N-(6-aminohexyl)-5-chloro-1-naphthalene sulphonamide directly blocks human ether à-go-go-related gene potassium channels stably expressed in human embryonic kidney 293 cells.
    Zhang XH; Jin MW; Sun HY; Zhang S; Li GR
    Br J Pharmacol; 2010 Oct; 161(4):872-84. PubMed ID: 20860665
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cyclovirobuxine D inhibits the currents of HERG potassium channels stably expressed in HEK293 cells.
    Zhao J; Wang Q; Xu J; Zhao J; Liu G; Peng S
    Eur J Pharmacol; 2011 Jun; 660(2-3):259-67. PubMed ID: 21497594
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inhibition of the rapid component of the delayed rectifier potassium current in ventricular myocytes by angiotensin II via the AT1 receptor.
    Wang YH; Shi CX; Dong F; Sheng JW; Xu YF
    Br J Pharmacol; 2008 May; 154(2):429-39. PubMed ID: 18414380
    [TBL] [Abstract][Full Text] [Related]  

  • 39. High affinity open channel block by dofetilide of HERG expressed in a human cell line.
    Snyders DJ; Chaudhary A
    Mol Pharmacol; 1996 Jun; 49(6):949-55. PubMed ID: 8649354
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dynamics of hERG closure allow novel insights into hERG blocking by small molecules.
    Schmidtke P; Ciantar M; Theret I; Ducrot P
    J Chem Inf Model; 2014 Aug; 54(8):2320-33. PubMed ID: 25000969
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 29.