BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

519 related articles for article (PubMed ID: 23034282)

  • 61. Decitabine priming enhances the antileukemic effects of exportin 1 (XPO1) selective inhibitor selinexor in acute myeloid leukemia.
    Ranganathan P; Yu X; Santhanam R; Hofstetter J; Walker A; Walsh K; Bhatnagar B; Klisovic R; Vasu S; Phelps MA; Devine S; Shacham S; Kauffman M; Marcucci G; Blum W; Garzon R
    Blood; 2015 Apr; 125(17):2689-92. PubMed ID: 25716206
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Structural basis for assembly and disassembly of the CRM1 nuclear export complex.
    Dong X; Biswas A; Chook YM
    Nat Struct Mol Biol; 2009 May; 16(5):558-60. PubMed ID: 19339972
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Inhibition of XPO1 with KPT-330 induces autophagy-dependent apoptosis in gallbladder cancer by activating the p53/mTOR pathway.
    Zhao C; Yang ZY; Zhang J; Li O; Liu SL; Cai C; Shu YJ; Pan LJ; Gong W; Dong P
    J Transl Med; 2022 Sep; 20(1):434. PubMed ID: 36180918
    [TBL] [Abstract][Full Text] [Related]  

  • 64. STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma.
    Miloudi H; Leroy K; Jardin F; Sola B
    Cell Signal; 2018 Jun; 46():76-82. PubMed ID: 29501729
    [TBL] [Abstract][Full Text] [Related]  

  • 65. XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid Leukemia by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus.
    Ranganathan P; Kashyap T; Yu X; Meng X; Lai TH; McNeil B; Bhatnagar B; Shacham S; Kauffman M; Dorrance AM; Blum W; Sampath D; Landesman Y; Garzon R
    Clin Cancer Res; 2016 Dec; 22(24):6142-6152. PubMed ID: 27358488
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in
    Zhang W; Ly C; Ishizawa J; Mu H; Ruvolo V; Shacham S; Daver N; Andreeff M
    Haematologica; 2018 Oct; 103(10):1642-1653. PubMed ID: 29773601
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies.
    Hing ZA; Fung HY; Ranganathan P; Mitchell S; El-Gamal D; Woyach JA; Williams K; Goettl VM; Smith J; Yu X; Meng X; Sun Q; Cagatay T; Lehman AM; Lucas DM; Baloglu E; Shacham S; Kauffman MG; Byrd JC; Chook YM; Garzon R; Lapalombella R
    Leukemia; 2016 Dec; 30(12):2364-2372. PubMed ID: 27323910
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Ratjadone and leptomycin B block CRM1-dependent nuclear export by identical mechanisms.
    Meissner T; Krause E; Vinkemeier U
    FEBS Lett; 2004 Oct; 576(1-2):27-30. PubMed ID: 15474004
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: analysis of the central role of XPO1.
    Cosson A; Chapiro E; Bougacha N; Lambert J; Herbi L; Cung HA; Algrin C; Keren B; Damm F; Gabillaud C; Brunelle-Navas MN; Davi F; Merle-Béral H; Le Garff-Tavernier M; Roos-Weil D; Choquet S; Uzunov M; Morel V; Leblond V; Maloum K; Lepretre S; Feugier P; Lesty C; Lejeune J; Sutton L; Landesman Y; Susin SA; Nguyen-Khac F
    Leukemia; 2017 Jul; 31(7):1625-1629. PubMed ID: 28344316
    [No Abstract]   [Full Text] [Related]  

  • 70. Verdinexor (KPT-335), a Selective Inhibitor of Nuclear Export, Reduces Respiratory Syncytial Virus Replication
    Jorquera PA; Mathew C; Pickens J; Williams C; Luczo JM; Tamir S; Ghildyal R; Tripp RA
    J Virol; 2019 Feb; 93(4):. PubMed ID: 30541831
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Selective inhibition of nuclear export: a promising approach in the shifting treatment paradigms for hematological neoplasms.
    Balasubramanian SK; Azmi AS; Maciejewski J
    Leukemia; 2022 Mar; 36(3):601-612. PubMed ID: 35091658
    [TBL] [Abstract][Full Text] [Related]  

  • 72. The Cellular Distribution of RanGAP1 Is Regulated by CRM1-Mediated Nuclear Export in Mammalian Cells.
    Cha K; Sen P; Raghunayakula S; Zhang XD
    PLoS One; 2015; 10(10):e0141309. PubMed ID: 26506250
    [TBL] [Abstract][Full Text] [Related]  

  • 73. CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications.
    Tai YT; Landesman Y; Acharya C; Calle Y; Zhong MY; Cea M; Tannenbaum D; Cagnetta A; Reagan M; Munshi AA; Senapedis W; Saint-Martin JR; Kashyap T; Shacham S; Kauffman M; Gu Y; Wu L; Ghobrial I; Zhan F; Kung AL; Schey SA; Richardson P; Munshi NC; Anderson KC
    Leukemia; 2014 Jan; 28(1):155-65. PubMed ID: 23588715
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Nuclear Export in Non-Hodgkin Lymphoma and Implications for Targeted XPO1 Inhibitors.
    Trkulja KL; Manji F; Kuruvilla J; Laister RC
    Biomolecules; 2023 Jan; 13(1):. PubMed ID: 36671496
    [TBL] [Abstract][Full Text] [Related]  

  • 75. XPO1-mediated nuclear export of RNF146 protects from angiotensin II-induced endothelial cellular injury.
    Sheng Z; Xu Y; Wang S; Yuan Y; Huang T; Lu P
    Biochem Biophys Res Commun; 2018 Sep; 503(3):1544-1549. PubMed ID: 30029878
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Upregulation of let-7f-2-3p by long noncoding RNA NEAT1 inhibits XPO1-mediated HAX-1 nuclear export in both in vitro and in vivo rodent models of doxorubicin-induced cardiotoxicity.
    Liu Y; Duan C; Liu W; Chen X; Wang Y; Liu X; Yue J; Yang J; Zhou X
    Arch Toxicol; 2019 Nov; 93(11):3261-3276. PubMed ID: 31570982
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
    Zanesi N; Aqeilan R; Drusco A; Kaou M; Sevignani C; Costinean S; Bortesi L; La Rocca G; Koldovsky P; Volinia S; Mancini R; Calin G; Scott CP; Pekarsky Y; Croce CM
    Cancer Res; 2006 Jan; 66(2):915-20. PubMed ID: 16424025
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines.
    Breit MN; Kisseberth WC; Bear MD; Landesman Y; Kashyap T; McCauley D; Kauffman MG; Shacham S; London CA
    BMC Vet Res; 2014 Jul; 10():160. PubMed ID: 25022346
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Promising SINEs for embargoing nuclear-cytoplasmic export as an anticancer strategy.
    Tan DS; Bedard PL; Kuruvilla J; Siu LL; Razak AR
    Cancer Discov; 2014 May; 4(5):527-37. PubMed ID: 24743138
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma.
    Zhang K; Wang M; Tamayo AT; Shacham S; Kauffman M; Lee J; Zhang L; Ou Z; Li C; Sun L; Ford RJ; Pham LV
    Exp Hematol; 2013 Jan; 41(1):67-78.e4. PubMed ID: 22986101
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 26.