BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

417 related articles for article (PubMed ID: 23035117)

  • 1. δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.
    Xu M; Liu K; Swaroop M; Porter FD; Sidhu R; Firnkes S; Ory DS; Marugan JJ; Xiao J; Southall N; Pavan WJ; Davidson C; Walkley SU; Remaley AT; Baxa U; Sun W; McKew JC; Austin CP; Zheng W
    J Biol Chem; 2012 Nov; 287(47):39349-60. PubMed ID: 23035117
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions.
    Yañez MJ; Marín T; Balboa E; Klein AD; Alvarez AR; Zanlungo S
    Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165875. PubMed ID: 32522631
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
    Newton J; Palladino END; Weigel C; Maceyka M; Gräler MH; Senkal CE; Enriz RD; Marvanova P; Jampilek J; Lima S; Milstien S; Spiegel S
    J Biol Chem; 2020 Jul; 295(27):9121-9133. PubMed ID: 32385114
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: similarities with Niemann-Pick type C disease.
    Chen J; Soni RK; Xu Y; Simoes S; Liang FX; DeFreitas L; Hwang R; Montesinos J; Lee JH; Area-Gomez E; Nandakumar R; Vardarajan B; Marquer C
    EBioMedicine; 2023 Jun; 92():104628. PubMed ID: 37245481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy.
    Yu D; Swaroop M; Wang M; Baxa U; Yang R; Yan Y; Coksaygan T; DeTolla L; Marugan JJ; Austin CP; McKew JC; Gong DW; Zheng W
    J Biomol Screen; 2014 Sep; 19(8):1164-73. PubMed ID: 24907126
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altered vitamin E status in Niemann-Pick type C disease.
    Ulatowski L; Parker R; Davidson C; Yanjanin N; Kelley TJ; Corey D; Atkinson J; Porter F; Arai H; Walkley SU; Manor D
    J Lipid Res; 2011 Jul; 52(7):1400-10. PubMed ID: 21550990
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells.
    Ebrahimi-Fakhari D; Wahlster L; Bartz F; Werenbeck-Ueding J; Praggastis M; Zhang J; Joggerst-Thomalla B; Theiss S; Grimm D; Ory DS; Runz H
    Hum Mol Genet; 2016 Aug; 25(16):3588-3599. PubMed ID: 27378690
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
    Boadu E; Nelson RC; Francis GA
    Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype.
    Argüello G; Balboa E; Tapia PJ; Castro J; Yañez MJ; Mattar P; Pulgar R; Zanlungo S
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33921734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.
    Lloyd-Evans E; Morgan AJ; He X; Smith DA; Elliot-Smith E; Sillence DJ; Churchill GC; Schuchman EH; Galione A; Platt FM
    Nat Med; 2008 Nov; 14(11):1247-55. PubMed ID: 18953351
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1.
    Singhal A; Szente L; Hildreth JEK; Song B
    Cell Death Dis; 2018 Oct; 9(10):1019. PubMed ID: 30282967
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endo-lysosomal dysfunction and neuronal-glial crosstalk in Niemann-Pick type C disease.
    Malara M; Prestel M; Tahirovic S
    Philos Trans R Soc Lond B Biol Sci; 2024 Apr; 379(1899):20220388. PubMed ID: 38368932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.
    Torres S; Matías N; Baulies A; Nuñez S; Alarcon-Vila C; Martinez L; Nuño N; Fernandez A; Caballeria J; Levade T; Gonzalez-Franquesa A; Garcia-Rovés P; Balboa E; Zanlungo S; Fabrías G; Casas J; Enrich C; Garcia-Ruiz C; Fernández-Checa JC
    Redox Biol; 2017 Apr; 11():60-72. PubMed ID: 27888692
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Endosomal/lysosomal processing of gangliosides affects neuronal cholesterol sequestration in Niemann-Pick disease type C.
    Zhou S; Davidson C; McGlynn R; Stephney G; Dobrenis K; Vanier MT; Walkley SU
    Am J Pathol; 2011 Aug; 179(2):890-902. PubMed ID: 21708114
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect.
    Devlin C; Pipalia NH; Liao X; Schuchman EH; Maxfield FR; Tabas I
    Traffic; 2010 May; 11(5):601-15. PubMed ID: 20412078
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.
    Newton J; Hait NC; Maceyka M; Colaco A; Maczis M; Wassif CA; Cougnoux A; Porter FD; Milstien S; Platt N; Platt FM; Spiegel S
    FASEB J; 2017 Apr; 31(4):1719-1730. PubMed ID: 28082351
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin.
    Vance JE; Karten B
    J Lipid Res; 2014 Aug; 55(8):1609-21. PubMed ID: 24664998
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.
    Long Y; Xu M; Li R; Dai S; Beers J; Chen G; Soheilian F; Baxa U; Wang M; Marugan JJ; Muro S; Li Z; Brady R; Zheng W
    Stem Cells Transl Med; 2016 Dec; 5(12):1644-1655. PubMed ID: 27484861
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pulmonary abnormalities in animal models due to Niemann-Pick type C1 (NPC1) or C2 (NPC2) disease.
    Roszell BR; Tao JQ; Yu KJ; Gao L; Huang S; Ning Y; Feinstein SI; Vite CH; Bates SR
    PLoS One; 2013; 8(7):e67084. PubMed ID: 23843985
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ontogenic changes in lung cholesterol metabolism, lipid content, and histology in mice with Niemann-Pick type C disease.
    Ramirez CM; Lopez AM; Le LQ; Posey KS; Weinberg AG; Turley SD
    Biochim Biophys Acta; 2014 Jan; 1841(1):54-61. PubMed ID: 24076310
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.