BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 23039228)

  • 1. Structure of RdxA--an oxygen-insensitive nitroreductase essential for metronidazole activation in Helicobacter pylori.
    Martínez-Júlvez M; Rojas AL; Olekhnovich I; Espinosa Angarica V; Hoffman PS; Sancho J
    FEBS J; 2012 Dec; 279(23):4306-17. PubMed ID: 23039228
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of the NAD(P)H oxidase and metronidazole reductase activities of the RdxA nitroreductase of Helicobacter pylori.
    Olekhnovich IN; Goodwin A; Hoffman PS
    FEBS J; 2009 Jun; 276(12):3354-64. PubMed ID: 19438716
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase.
    Goodwin A; Kersulyte D; Sisson G; Veldhuyzen van Zanten SJ; Berg DE; Hoffman PS
    Mol Microbiol; 1998 Apr; 28(2):383-93. PubMed ID: 9622362
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori.
    Tu IF; Liao JH; Yang FL; Lin NT; Chan HL; Wu SH
    Helicobacter; 2014 Oct; 19(5):356-66. PubMed ID: 24834789
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of the genes rdxA and frxA involved in metronidazole resistance in Helicobacter pylori.
    Marais A; Bilardi C; Cantet F; Mendz GL; Mégraud F
    Res Microbiol; 2003 Mar; 154(2):137-44. PubMed ID: 12648728
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Frequent association between alteration of the rdxA gene and metronidazole resistance in French and North African isolates of Helicobacter pylori.
    Tankovic J; Lamarque D; Delchier JC; Soussy CJ; Labigne A; Jenks PJ
    Antimicrob Agents Chemother; 2000 Mar; 44(3):608-13. PubMed ID: 10681326
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Frequency of Helicobacter pylori nitroreductase RdxA mutations for metronidazole activation in a population in the Cauca Department, Colombia].
    Acosta CP; Quiroga AJ; Sierra CH; Trespalacios AA
    Biomedica; 2017 Jun; 37(2):191-199. PubMed ID: 28527283
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potential involvement of several nitroreductases in metronidazole resistance in Helicobacter pylori.
    Jorgensen MA; Trend MA; Hazell SL; Mendz GL
    Arch Biochem Biophys; 2001 Aug; 392(2):180-91. PubMed ID: 11488591
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of allelic variants of rdxA associated with metronidazole resistance in Helicobacter pylori: detection of common genotypes in rdxA by multiplex allele-specific polymerase chain reaction.
    Butlop TR; Mungkote NT; Chaichanawongsaroj NT
    Genet Mol Res; 2016 Sep; 15(3):. PubMed ID: 27706703
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enzymes associated with reductive activation and action of nitazoxanide, nitrofurans, and metronidazole in Helicobacter pylori.
    Sisson G; Goodwin A; Raudonikiene A; Hughes NJ; Mukhopadhyay AK; Berg DE; Hoffman PS
    Antimicrob Agents Chemother; 2002 Jul; 46(7):2116-23. PubMed ID: 12069963
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the rdxA and frxA genes in oxygen-dependent metronidazole resistance of Helicobacter pylori.
    Gerrits MM; van der Wouden EJ; Bax DA; van Zwet AA; van Vliet AH; de Jong A; Kusters JG; Thijs JC; Kuipers EJ
    J Med Microbiol; 2004 Nov; 53(Pt 11):1123-1128. PubMed ID: 15496391
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori.
    Jeong JY; Mukhopadhyay AK; Dailidiene D; Wang Y; Velapatiño B; Gilman RH; Parkinson AJ; Nair GB; Wong BC; Lam SK; Mistry R; Segal I; Yuan Y; Gao H; Alarcon T; Brea ML; Ito Y; Kersulyte D; Lee HK; Gong Y; Goodwin A; Hoffman PS; Berg DE
    J Bacteriol; 2000 Sep; 182(18):5082-90. PubMed ID: 10960091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Analysis of rdxA and involvement of additional genes encoding NAD(P)H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori.
    Kwon DH; El-Zaatari FA; Kato M; Osato MS; Reddy R; Yamaoka Y; Graham DY
    Antimicrob Agents Chemother; 2000 Aug; 44(8):2133-42. PubMed ID: 10898687
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of the rdxA gene in high-level metronidazole-resistant clinical isolates confirms a limited use of rdxA mutations as a marker for prediction of metronidazole resistance in Helicobacter pylori.
    Bereswill S; Krainick C; Stähler F; Herrmann L; Kist M
    FEMS Immunol Med Microbiol; 2003 May; 36(3):193-8. PubMed ID: 12738391
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A redox basis for metronidazole resistance in Helicobacter pylori.
    Kaakoush NO; Asencio C; Mégraud F; Mendz GL
    Antimicrob Agents Chemother; 2009 May; 53(5):1884-91. PubMed ID: 19223619
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Contingency nature of Helicobacter bizzozeronii oxygen-insensitive NAD(P)H-nitroreductase (HBZC1_00960) and its role in metronidazole resistance.
    Kondadi PK; Pacini C; Revez J; Hänninen ML; Rossi M
    Vet Res; 2013 Jul; 44(1):56. PubMed ID: 23865636
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic analysis of Helicobacter pylori clinical isolates suggests resistance to metronidazole can occur without the loss of functional rdxA.
    Kim SY; Joo YM; Lee HS; Chung IS; Yoo YJ; Merrell DS; Cha JH
    J Antibiot (Tokyo); 2009 Jan; 62(1):43-50. PubMed ID: 19132060
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The rdxA gene plays a more major role than frxA gene mutation in high-level metronidazole resistance of Helicobacter pylori in Taiwan.
    Yang YJ; Wu JJ; Sheu BS; Kao AW; Huang AH
    Helicobacter; 2004 Oct; 9(5):400-7. PubMed ID: 15361078
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutations in Helicobacter pylori rdxA gene sequences may not contribute to metronidazole resistance.
    Chisholm SA; Owen RJ
    J Antimicrob Chemother; 2003 Apr; 51(4):995-9. PubMed ID: 12654749
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Study of rdxA and frxA genes mutations in metronidazole-resistant and -susceptible Helicobacter pylori clinical isolates from the central region of Portugal.
    Marques B; Donato MM; Cardoso O; Luxo C; Martinho A; Almeida N
    J Glob Antimicrob Resist; 2019 Jun; 17():300-304. PubMed ID: 30658199
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.