These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 23039820)

  • 1. Structure-based identification of aporphines with selective 5-HT(2A) receptor-binding activity.
    Munusamy V; Yap BK; Buckle MJ; Doughty SW; Chung LY
    Chem Biol Drug Des; 2013 Feb; 81(2):250-6. PubMed ID: 23039820
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
    Fiorino F; Perissutti E; Severino B; Santagada V; Cirillo D; Terracciano S; Massarelli P; Bruni G; Collavoli E; Renner C; Caliendo G
    J Med Chem; 2005 Aug; 48(17):5495-503. PubMed ID: 16107148
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular modeling and docking studies of human 5-hydroxytryptamine 2A (5-HT2A) receptor for the identification of hotspots for ligand binding.
    Kanagarajadurai K; Malini M; Bhattacharya A; Panicker MM; Sowdhamini R
    Mol Biosyst; 2009 Dec; 5(12):1877-88. PubMed ID: 19763327
    [TBL] [Abstract][Full Text] [Related]  

  • 4. R-(-)-N-alkyl-11-hydroxy-10-hydroxymethyl- and 10-methyl-aporphines as 5-HT1A receptor ligands.
    Si YG; Gardner MP; Tarazi FI; Baldessarini RJ; Neumeyer JL
    Bioorg Med Chem Lett; 2007 Aug; 17(15):4128-30. PubMed ID: 17543523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of dihydrofuroaporphine derivatives: identification of a potent and selective serotonin 5-HT 1A receptor agonist.
    Liu Z; Zhang H; Ye N; Zhang J; Wu Q; Sun P; Li L; Zhen X; Zhang A
    J Med Chem; 2010 Feb; 53(3):1319-28. PubMed ID: 20041669
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands.
    Chambers JJ; Parrish JC; Jensen NH; Kurrasch-Orbaugh DM; Marona-Lewicka D; Nichols DE
    J Med Chem; 2003 Jul; 46(16):3526-35. PubMed ID: 12877591
    [TBL] [Abstract][Full Text] [Related]  

  • 7. C4 phenyl aporphines with selective h5-HT(2B) receptor affinity.
    Kapadia N; Harding WW
    Bioorg Med Chem Lett; 2015 Sep; 25(17):3451-4. PubMed ID: 26227772
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S; Kołaczkowski M; Maryniak E; Zajdel P; Pawłowski M; Tatarczyńska E; Kłodzińska A; Chojnacka-Wójcik E; Bojarski AJ; Charakchieva-Minol S; Duszyńska B; Nowak G; Maciag D
    J Med Chem; 2004 May; 47(10):2659-66. PubMed ID: 15115407
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile.
    Sun H; Zhu L; Yang H; Qian W; Guo L; Zhou S; Gao B; Li Z; Zhou Y; Jiang H; Chen K; Zhen X; Liu H
    Bioorg Med Chem; 2013 Feb; 21(4):856-68. PubMed ID: 23332346
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and structural investigation of some pyrimido[5,4-c]quinolin-4(3H)-one derivatives with a long-chain arylpiperazine moiety as potent 5-HT(1A/2A) and 5-HT(7) receptor ligands.
    Lewgowd W; Bojarski AJ; Szczesio M; Olczak A; Glowka ML; Mordalski S; Stanczak A
    Eur J Med Chem; 2011 Aug; 46(8):3348-61. PubMed ID: 21601317
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists.
    Braden MR; Parrish JC; Naylor JC; Nichols DE
    Mol Pharmacol; 2006 Dec; 70(6):1956-64. PubMed ID: 17000863
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N-Propylnoraporphin-11-O-yl carboxylic esters as potent dopamine D(2) and serotonin 5-HT(1A) receptor dual ligands.
    Liu Z; Chen X; Sun P; Yu L; Zhen X; Zhang A
    Bioorg Med Chem; 2008 Sep; 16(18):8335-8. PubMed ID: 18783955
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A new class of arylpiperazine derivatives: the library synthesis on SynPhase lanterns and biological evaluation on serotonin 5-HT(1A) and 5-HT(2A) receptors.
    Zajdel P; Subra G; Bojarski AJ; Duszyńska B; Pawłowski M; Martinez J
    J Comb Chem; 2004; 6(5):761-7. PubMed ID: 15360211
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Position 5.46 of the serotonin 5-HT2A receptor contributes to a species-dependent variation for the 5-HT2C agonist (R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol-6(2H)-one: impact on selectivity and toxicological evaluation.
    Miller KJ; Wu GY; Varnes JG; Levesque P; Li J; Li D; Robl JA; Rossi KA; Wacker DA
    Mol Pharmacol; 2009 Dec; 76(6):1211-9. PubMed ID: 19767451
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ; Paluchowska MH; Duszyńska B; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
    Bioorg Med Chem; 2005 Mar; 13(6):2293-303. PubMed ID: 15727878
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New aporphinoid 5-HT2A and α1A antagonists via structural manipulations of nantenine.
    Chaudhary S; Ponnala S; Legendre O; Gonzales JA; Navarro HA; Harding WW
    Bioorg Med Chem; 2011 Oct; 19(19):5861-8. PubMed ID: 21900013
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and pharmacological investigation of novel 2-aminothiazole-privileged aporphines.
    Liu Z; Chen X; Yu L; Zhen X; Zhang A
    Bioorg Med Chem; 2008 Jul; 16(14):6675-81. PubMed ID: 18562201
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Homology modeling of the human 5-HT1A, 5-HT 2A, D1, and D2 receptors: model refinement with molecular dynamics simulations and docking evaluation.
    Yap BK; Buckle MJ; Doughty SW
    J Mol Model; 2012 Aug; 18(8):3639-55. PubMed ID: 22354276
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Affinity of cyamemazine metabolites for serotonin, histamine and dopamine receptor subtypes.
    Benyamina A; Arbus C; Nuss P; Garay RP; Neliat G; Hameg A
    Eur J Pharmacol; 2008 Jan; 578(2-3):142-7. PubMed ID: 17936750
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New potent 5-HT(2A) receptor ligands containing an N'-cyanopicolinamidine nucleus: Synthesis and in vitro pharmacological evaluation.
    Fiorino F; Severino B; Magli E; Perissutti E; Frecentese F; Esposito A; Incisivo GM; Ciano A; Massarelli P; Nencini C; Santagada V; Caliendo G
    Eur J Med Chem; 2012 Jan; 47(1):520-9. PubMed ID: 22133459
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.