BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 23040068)

  • 1. Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARγ and RhoA/Rho-kinase.
    Pelham CJ; Ketsawatsomkron P; Groh S; Grobe JL; de Lange WJ; Ibeawuchi SR; Keen HL; Weatherford ET; Faraci FM; Sigmund CD
    Cell Metab; 2012 Oct; 16(4):462-72. PubMed ID: 23040068
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity.
    Mukohda M; Fang S; Wu J; Agbor LN; Nair AR; Ibeawuchi SC; Hu C; Liu X; Lu KT; Guo DF; Davis DR; Keen HL; Quelle FW; Sigmund CD
    J Clin Invest; 2019 Mar; 129(6):2318-2332. PubMed ID: 30896450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism.
    Agbor LN; Ibeawuchi SC; Hu C; Wu J; Davis DR; Keen HL; Quelle FW; Sigmund CD
    JCI Insight; 2016 Nov; 1(19):e91015. PubMed ID: 27882355
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dysfunction of Cullin 3 RING E3 ubiquitin ligase causes vasoconstriction and increased sodium reabsorption in diabetes.
    Zhang Y; Guo Q; Jiang G; Zhang C
    Arch Biochem Biophys; 2021 Oct; 710():109000. PubMed ID: 34343486
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The 2023 Walter B. Cannon Award Lecture: Mechanisms Regulating Vascular Function and Blood Pressure by the PPARγ-RhoBTB1-CUL3 Pathway.
    Sigmund CD
    Function (Oxf); 2024; 5(1):zqad071. PubMed ID: 38196837
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PPARγ regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity.
    Ketsawatsomkron P; Lorca RA; Keen HL; Weatherford ET; Liu X; Pelham CJ; Grobe JL; Faraci FM; England SK; Sigmund CD
    Circ Res; 2012 Nov; 111(11):1446-58. PubMed ID: 22962432
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aryl hydrocarbon receptor (AhR) regulates adipocyte differentiation by assembling CRL4B ubiquitin ligase to target PPARγ for proteasomal degradation.
    Dou H; Duan Y; Zhang X; Yu Q; Di Q; Song Y; Li P; Gong Y
    J Biol Chem; 2019 Nov; 294(48):18504-18515. PubMed ID: 31653699
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dominant negative PPARγ promotes atherosclerosis, vascular dysfunction, and hypertension through distinct effects in endothelium and vascular muscle.
    Pelham CJ; Keen HL; Lentz SR; Sigmund CD
    Am J Physiol Regul Integr Comp Physiol; 2013 May; 304(9):R690-701. PubMed ID: 23447133
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Lbc Rho guanine nucleotide exchange factor α-catulin axis functions in serotonin-induced vascular smooth muscle cell mitogenesis and RhoA/ROCK activation.
    Bear MD; Li M; Liu Y; Giel-Moloney MA; Fanburg BL; Toksoz D
    J Biol Chem; 2010 Oct; 285(43):32919-32926. PubMed ID: 20696764
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator-Activated Receptor-γ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate-Salt Hypertension.
    Ketsawatsomkron P; Keen HL; Davis DR; Lu KT; Stump M; De Silva TM; Hilzendeger AM; Grobe JL; Faraci FM; Sigmund CD
    Hypertension; 2016 Jan; 67(1):214-22. PubMed ID: 26597823
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LncRNA-SMILR modulates RhoA/ROCK signaling by targeting miR-141 to regulate vascular remodeling in pulmonary arterial hypertension.
    Lei S; Peng F; Li ML; Duan WB; Peng CQ; Wu SJ
    Am J Physiol Heart Circ Physiol; 2020 Aug; 319(2):H377-H391. PubMed ID: 32559140
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation.
    Ying Z; Giachini FR; Tostes RC; Webb RC
    Cardiovasc Res; 2009 Jul; 83(1):155-62. PubMed ID: 19276129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PPARγ and RhoBTB1 in hypertension.
    Fang S; Sigmund CD
    Curr Opin Nephrol Hypertens; 2020 Mar; 29(2):161-170. PubMed ID: 31789920
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of cold-sensing transient receptor potential melastatin subtype 8 antagonizes vasoconstriction and hypertension through attenuating RhoA/Rho kinase pathway.
    Sun J; Yang T; Wang P; Ma S; Zhu Z; Pu Y; Li L; Zhao Y; Xiong S; Liu D; Zhu Z
    Hypertension; 2014 Jun; 63(6):1354-63. PubMed ID: 24637663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In Vitro and In Vivo Approaches to Assess Rho Kinase Activity.
    Sauzeau V; Loirand G
    Methods Mol Biol; 2017; 1527():213-218. PubMed ID: 28116719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic interference with peroxisome proliferator-activated receptor γ in smooth muscle enhances myogenic tone in the cerebrovasculature via A Rho kinase-dependent mechanism.
    De Silva TM; Ketsawatsomkron P; Pelham C; Sigmund CD; Faraci FM
    Hypertension; 2015 Feb; 65(2):345-51. PubMed ID: 25385762
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo.
    Hasan DM; Starke RM; Gu H; Wilson K; Chu Y; Chalouhi N; Heistad DD; Faraci FM; Sigmund CD
    Hypertension; 2015 Jul; 66(1):211-20. PubMed ID: 25916724
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of calcium-independent phospholipase A2beta in high glucose-induced activation of RhoA, Rho kinase, and CPI-17 in cultured vascular smooth muscle cells and vascular smooth muscle hypercontractility in diabetic animals.
    Xie Z; Gong MC; Su W; Xie D; Turk J; Guo Z
    J Biol Chem; 2010 Mar; 285(12):8628-38. PubMed ID: 20086008
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells.
    Alexis JD; Wang N; Che W; Lerner-Marmarosh N; Sahni A; Korshunov VA; Zou Y; Ding B; Yan C; Berk BC; Abe J
    Circ Res; 2009 Jan; 104(1):69-78. PubMed ID: 19023129
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Resveratrol prevents AngII-induced hypertension via AMPK activation and RhoA/ROCK suppression in mice.
    Cao X; Luo T; Luo X; Tang Z
    Hypertens Res; 2014 Sep; 37(9):803-10. PubMed ID: 24965170
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.