BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 23040895)

  • 1. Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitors.
    Su X; Halem HA; Thomas MP; Moutrille C; Culler MD; Vicker N; Potter BV
    Bioorg Med Chem; 2012 Nov; 20(21):6394-402. PubMed ID: 23040895
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors.
    Su X; Pradaux-Caggiano F; Thomas MP; Szeto MW; Halem HA; Culler MD; Vicker N; Potter BV
    ChemMedChem; 2010 Jul; 5(7):1026-44. PubMed ID: 20486152
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1.
    Su X; Pradaux-Caggiano F; Vicker N; Thomas MP; Halem H; Culler MD; Potter BV
    ChemMedChem; 2011 Sep; 6(9):1616-29. PubMed ID: 21714097
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors.
    Su X; Vicker N; Thomas MP; Pradaux-Caggiano F; Halem H; Culler MD; Potter BV
    ChemMedChem; 2011 Aug; 6(8):1439-51. PubMed ID: 21608132
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group.
    Kwon SW; Kang SK; Lee JH; Bok JH; Kim CH; Dal Rhee S; Jung WH; Kim HY; Bae MA; Song JS; Ha DC; Cheon HG; Kim KY; Ahn JH
    Bioorg Med Chem Lett; 2011 Jan; 21(1):435-9. PubMed ID: 21093259
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.
    Webster SP; Ward P; Binnie M; Craigie E; McConnell KM; Sooy K; Vinter A; Seckl JR; Walker BR
    Bioorg Med Chem Lett; 2007 May; 17(10):2838-43. PubMed ID: 17350260
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Su X; Vicker N; Trusselle M; Halem H; Culler MD; Potter BV
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):169-73. PubMed ID: 18775471
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors.
    Cheng H; Hoffman J; Le P; Nair SK; Cripps S; Matthews J; Smith C; Yang M; Kupchinsky S; Dress K; Edwards M; Cole B; Walters E; Loh C; Ermolieff J; Fanjul A; Bhat GB; Herrera J; Pauly T; Hosea N; Paderes G; Rejto P
    Bioorg Med Chem Lett; 2010 May; 20(9):2897-902. PubMed ID: 20363126
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of cyclicsulfonamide derivatives with an acetamide group as 11β-hydroxysteroid dehydrogenase 1 inhibitors.
    Kim SH; Kwon SW; Chu SY; Lee JH; Narsaiah B; Kim CH; Kang SK; Kang NS; Rhee SD; Bae MA; Ahn SH; Ha DC; Kim KY; Ahn JH
    Chem Pharm Bull (Tokyo); 2011; 59(1):46-52. PubMed ID: 21212546
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery and optimization of adamantyl carbamate inhibitors of 11β-HSD1.
    Tice CM; Zhao W; Krosky PM; Kruk BA; Berbaum J; Johnson JA; Bukhtiyarov Y; Panemangalore R; Scott BB; Zhao Y; Bruno JG; Howard L; Togias J; Ye YJ; Singh SB; McKeever BM; Lindblom PR; Guo J; Guo R; Nar H; Schuler-Metz A; Gregg RE; Leftheris K; Harrison RK; McGeehan GM; Zhuang L; Claremon DA
    Bioorg Med Chem Lett; 2010 Nov; 20(22):6725-9. PubMed ID: 20864344
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors.
    Valverde E; Seira C; McBride A; Binnie M; Luque FJ; Webster SP; Bidon-Chanal A; Vázquez S
    Bioorg Med Chem; 2015 Dec; 23(24):7607-17. PubMed ID: 26596711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold.
    Leiva R; Seira C; McBride A; Binnie M; Luque FJ; Bidon-Chanal A; Webster SP; Vázquez S
    Bioorg Med Chem Lett; 2015 Oct; 25(19):4250-3. PubMed ID: 26306982
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and structure-activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1).
    Ye XY; Yoon D; Chen SY; Nayeem A; Golla R; Seethala R; Wang M; Harper T; Sleczka BG; Apedo A; Li YX; He B; Kirby M; Gordon DA; Robl JA
    Bioorg Med Chem Lett; 2014 Jan; 24(2):654-60. PubMed ID: 24360604
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel highly potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, UI-1499.
    Byun SY; Shin YJ; Nam KY; Hong SP; Ahn SK
    Life Sci; 2015 Jan; 120():1-7. PubMed ID: 25447448
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements.
    Yeh VS; Kurukulasuriya R; Madar D; Patel JR; Fung S; Monzon K; Chiou W; Wang J; Jacobson P; Sham HL; Link JT
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5408-13. PubMed ID: 16890427
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
    Roche D; Carniato D; Leriche C; Lepifre F; Christmann-Franck S; Graedler U; Charon C; Bozec S; Doare L; Schmidlin F; Lecomte M; Valeur E
    Bioorg Med Chem Lett; 2009 May; 19(10):2674-8. PubMed ID: 19395260
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.
    Yeh VS; Patel JR; Yong H; Kurukulasuriya R; Fung S; Monzon K; Chiou W; Wang J; Stolarik D; Imade H; Beno D; Brune M; Jacobson P; Sham H; Link JT
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5414-9. PubMed ID: 16899366
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors.
    Paderes GD; Dress K; Huang B; Elleraas J; Rejto PA; Pauly T
    Methods Mol Biol; 2011; 685():191-215. PubMed ID: 20981525
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel highly potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, INU-101.
    Hong SP; Han D; Chang KH; Ahn SK
    Eur J Pharmacol; 2018 Sep; 835():169-178. PubMed ID: 30096297
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diazepane-acetamide derivatives as selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.
    Odermatt A
    Expert Opin Ther Pat; 2009 Oct; 19(10):1477-83. PubMed ID: 19780703
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.