333 related articles for article (PubMed ID: 23041316)
1. Reactivation of latent HIV-1 by inhibition of BRD4.
Zhu J; Gaiha GD; John SP; Pertel T; Chin CR; Gao G; Qu H; Walker BD; Elledge SJ; Brass AL
Cell Rep; 2012 Oct; 2(4):807-16. PubMed ID: 23041316
[TBL] [Abstract][Full Text] [Related]
2. The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation.
Li Z; Guo J; Wu Y; Zhou Q
Nucleic Acids Res; 2013 Jan; 41(1):277-87. PubMed ID: 23087374
[TBL] [Abstract][Full Text] [Related]
3. BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.
Boehm D; Calvanese V; Dar RD; Xing S; Schroeder S; Martins L; Aull K; Li PC; Planelles V; Bradner JE; Zhou MM; Siliciano RF; Weinberger L; Verdin E; Ott M
Cell Cycle; 2013 Feb; 12(3):452-62. PubMed ID: 23255218
[TBL] [Abstract][Full Text] [Related]
4. A New Quinoline BRD4 Inhibitor Targets a Distinct Latent HIV-1 Reservoir for Reactivation from Other "Shock" Drugs.
Abner E; Stoszko M; Zeng L; Chen HC; Izquierdo-Bouldstridge A; Konuma T; Zorita E; Fanunza E; Zhang Q; Mahmoudi T; Zhou MM; Filion GJ; Jordan A
J Virol; 2018 May; 92(10):. PubMed ID: 29343578
[TBL] [Abstract][Full Text] [Related]
5. A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNP.
Wang C; Yang S; Lu H; You H; Ni M; Shan W; Lin T; Gao X; Chen H; Zhou Q; Xue Y
PLoS One; 2015; 10(11):e0142739. PubMed ID: 26569506
[TBL] [Abstract][Full Text] [Related]
6. HIV latency reversing agents act through Tat post translational modifications.
Khoury G; Mota TM; Li S; Tumpach C; Lee MY; Jacobson J; Harty L; Anderson JL; Lewin SR; Purcell DFJ
Retrovirology; 2018 May; 15(1):36. PubMed ID: 29751762
[TBL] [Abstract][Full Text] [Related]
7. BET bromodomain inhibition as a novel strategy for reactivation of HIV-1.
Banerjee C; Archin N; Michaels D; Belkina AC; Denis GV; Bradner J; Sebastiani P; Margolis DM; Montano M
J Leukoc Biol; 2012 Dec; 92(6):1147-54. PubMed ID: 22802445
[TBL] [Abstract][Full Text] [Related]
8. 4-Deoxyphorbol inhibits HIV-1 infection in synergism with antiretroviral drugs and reactivates viral reservoirs through PKC/MEK activation synergizing with vorinostat.
De la Torre-Tarazona HE; Jiménez R; Bueno P; Camarero S; Román L; Fernández-García JL; Beltrán M; Nothias LF; Cachet X; Paolini J; Litaudon M; Alcami J; Bedoya LM
Biochem Pharmacol; 2020 Jul; 177():113937. PubMed ID: 32224142
[TBL] [Abstract][Full Text] [Related]
9. The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes.
Conrad RJ; Fozouni P; Thomas S; Sy H; Zhang Q; Zhou MM; Ott M
Mol Cell; 2017 Sep; 67(6):1001-1012.e6. PubMed ID: 28844864
[TBL] [Abstract][Full Text] [Related]
10. Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C-induced HIV latency reversal.
Matsuda K; Kobayakawa T; Tsuchiya K; Hattori SI; Nomura W; Gatanaga H; Yoshimura K; Oka S; Endo Y; Tamamura H; Mitsuya H; Maeda K
J Biol Chem; 2019 Jan; 294(1):116-129. PubMed ID: 30413535
[TBL] [Abstract][Full Text] [Related]
11. Temporal transcriptional response to latency reversing agents identifies specific factors regulating HIV-1 viral transcriptional switch.
Venkatachari NJ; Zerbato JM; Jain S; Mancini AE; Chattopadhyay A; Sluis-Cremer N; Bar-Joseph Z; Ayyavoo V
Retrovirology; 2015 Oct; 12():85. PubMed ID: 26438393
[TBL] [Abstract][Full Text] [Related]
12. Long Noncoding RNA uc002yug.2 Activates HIV-1 Latency through Regulation of mRNA Levels of Various RUNX1 Isoforms and Increased Tat Expression.
Huan C; Li Z; Ning S; Wang H; Yu XF; Zhang W
J Virol; 2018 May; 92(9):. PubMed ID: 29491162
[TBL] [Abstract][Full Text] [Related]
13. The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency.
Li Z; Mbonye U; Feng Z; Wang X; Gao X; Karn J; Zhou Q
PLoS Pathog; 2018 Apr; 14(4):e1007012. PubMed ID: 29684085
[TBL] [Abstract][Full Text] [Related]
14. The Novel PKC Activator 10-Methyl-Aplog-1 Combined with JQ1 Induced Strong and Synergistic HIV Reactivation with Tolerable Global T Cell Activation.
Washizaki A; Murata M; Seki Y; Kikumori M; Tang Y; Tan W; Wardani NP; Irie K; Akari H
Viruses; 2021 Oct; 13(10):. PubMed ID: 34696466
[TBL] [Abstract][Full Text] [Related]
15. Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV.
Niu Q; Liu Z; Alamer E; Fan X; Chen H; Endsley J; Gelman BB; Tian B; Kim JH; Michael NL; Robb ML; Ananworanich J; Zhou J; Hu H
J Clin Invest; 2019 Jul; 129(8):3361-3373. PubMed ID: 31329163
[TBL] [Abstract][Full Text] [Related]
16. Posttranscriptional Regulation of HIV-1 Gene Expression during Replication and Reactivation from Latency by Nuclear Matrix Protein MATR3.
Sarracino A; Gharu L; Kula A; Pasternak AO; Avettand-Fenoel V; Rouzioux C; Bardina M; De Wit S; Benkirane M; Berkhout B; Van Lint C; Marcello A
mBio; 2018 Nov; 9(6):. PubMed ID: 30425153
[TBL] [Abstract][Full Text] [Related]
17. Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue.
Biancotto A; Grivel JC; Gondois-Rey F; Bettendroffer L; Vigne R; Brown S; Margolis LB; Hirsch I
J Virol; 2004 Oct; 78(19):10507-15. PubMed ID: 15367617
[TBL] [Abstract][Full Text] [Related]
18. Bromodomain and extraterminal inhibitors block the Epstein-Barr virus lytic cycle at two distinct steps.
Keck KM; Moquin SA; He A; Fernandez SG; Somberg JJ; Liu SM; Martinez DM; Miranda JL
J Biol Chem; 2017 Aug; 292(32):13284-13295. PubMed ID: 28588024
[TBL] [Abstract][Full Text] [Related]
19. Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication.
Campbell GR; Bruckman RS; Herns SD; Joshi S; Durden DL; Spector SA
J Biol Chem; 2018 Apr; 293(16):5808-5820. PubMed ID: 29475942
[TBL] [Abstract][Full Text] [Related]
20. Differential effects of phorbol-13-monoesters on human immunodeficiency virus reactivation.
Márquez N; Calzado MA; Sánchez-Duffhues G; Pérez M; Minassi A; Pagani A; Appendino G; Diaz L; Muñoz-Fernández MA; Muñoz E
Biochem Pharmacol; 2008 Mar; 75(6):1370-80. PubMed ID: 18241838
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
