96 related articles for article (PubMed ID: 23041456)
1. The Substrate-Activity-Screening methodology applied to receptor tyrosine kinases: a proof-of-concept study.
Chapelat J; Berst F; Marzinzik AL; Moebitz H; Drueckes P; Trappe J; Fabbro D; Seebach D
Eur J Med Chem; 2012 Nov; 57():1-9. PubMed ID: 23041456
[TBL] [Abstract][Full Text] [Related]
2. Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition.
Peng SB; Yan L; Xia X; Watkins SA; Brooks HB; Beight D; Herron DK; Jones ML; Lampe JW; McMillen WT; Mort N; Sawyer JS; Yingling JM
Biochemistry; 2005 Feb; 44(7):2293-304. PubMed ID: 15709742
[TBL] [Abstract][Full Text] [Related]
3. Integrating ligand-based and protein-centric virtual screening of kinase inhibitors using ensembles of multiple protein kinase genes and conformations.
Dixit A; Verkhivker GM
J Chem Inf Model; 2012 Oct; 52(10):2501-15. PubMed ID: 22992037
[TBL] [Abstract][Full Text] [Related]
4. Substrate profiling of IGF-1R and InsR: identification of a potent pentamer substrate.
Chapelat J; Berst F; Marzinzik AL; Moebitz H; Drueckes P; Fabbro D; Trappe J; Seebach D
Bioorg Med Chem Lett; 2011 Dec; 21(23):7030-3. PubMed ID: 22004721
[TBL] [Abstract][Full Text] [Related]
5. Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.
Comess KM; Sun C; Abad-Zapatero C; Goedken ER; Gum RJ; Borhani DW; Argiriadi M; Groebe DR; Jia Y; Clampit JE; Haasch DL; Smith HT; Wang S; Song D; Coen ML; Cloutier TE; Tang H; Cheng X; Quinn C; Liu B; Xin Z; Liu G; Fry EH; Stoll V; Ng TI; Banach D; Marcotte D; Burns DJ; Calderwood DJ; Hajduk PJ
ACS Chem Biol; 2011 Mar; 6(3):234-44. PubMed ID: 21090814
[TBL] [Abstract][Full Text] [Related]
6. High-throughput, cell-free, liposome-based approach for assessing in vitro activity of lipid kinases.
Demian DJ; Clugston SL; Foster MM; Rameh L; Sarkes D; Townson SA; Yang L; Zhang M; Charlton ME
J Biomol Screen; 2009 Aug; 14(7):838-44. PubMed ID: 19641220
[TBL] [Abstract][Full Text] [Related]
7. Exquisitely specific bisubstrate inhibitors of c-Src kinase.
Brandvold KR; Santos SM; Breen ME; Lachacz EJ; Steffey ME; Soellner MB
ACS Chem Biol; 2015 Jun; 10(6):1387-91. PubMed ID: 25793938
[TBL] [Abstract][Full Text] [Related]
8. MALDI-TOF mass-spectrometry-based versatile method for the characterization of protein kinases.
Kondo N; Nishimura S
Chemistry; 2009; 15(6):1413-21. PubMed ID: 19115309
[TBL] [Abstract][Full Text] [Related]
9. Tricyclic azepine derivatives: pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors.
Smith L; Piatnitski EL; Kiselyov AS; Ouyang X; Chen X; Burdzovic-Wizemann S; Xu Y; Pan W; Chen X; Wang Y; Rosler RL; Patel SN; Chiang HH; Milligan DL; Columbus J; Wong WC; Doody JF; Hadari YR
Bioorg Med Chem Lett; 2006 Mar; 16(6):1643-6. PubMed ID: 16412636
[TBL] [Abstract][Full Text] [Related]
10. Hit-to-lead studies on benzimidazole inhibitors of ITK: discovery of a novel class of kinase inhibitors.
Snow RJ; Abeywardane A; Campbell S; Lord J; Kashem MA; Khine HH; King J; Kowalski JA; Pullen SS; Roma T; Roth GP; Sarko CR; Wilson NS; Winters MP; Wolak JP; Cywin CL
Bioorg Med Chem Lett; 2007 Jul; 17(13):3660-5. PubMed ID: 17499505
[TBL] [Abstract][Full Text] [Related]
11. Development of natural product-derived receptor tyrosine kinase inhibitors based on conservation of protein domain fold.
Kissau L; Stahl P; Mazitschek R; Giannis A; Waldmann H
J Med Chem; 2003 Jul; 46(14):2917-31. PubMed ID: 12825933
[TBL] [Abstract][Full Text] [Related]
12. Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening.
Usui T; Ban HS; Kawada J; Hirokawa T; Nakamura H
Bioorg Med Chem Lett; 2008 Jan; 18(1):285-8. PubMed ID: 17983745
[TBL] [Abstract][Full Text] [Related]
13. A high-throughput, nonisotopic, competitive binding assay for kinases using nonselective inhibitor probes (ED-NSIP).
Vainshtein I; Silveria S; Kaul P; Rouhani R; Eglen RM; Wang J
J Biomol Screen; 2002 Dec; 7(6):507-14. PubMed ID: 14599348
[TBL] [Abstract][Full Text] [Related]
14. Peptide and protein phosphorylation by protein tyrosine kinase Csk: insights into specificity and mechanism.
Sondhi D; Xu W; Songyang Z; Eck MJ; Cole PA
Biochemistry; 1998 Jan; 37(1):165-72. PubMed ID: 9425036
[TBL] [Abstract][Full Text] [Related]
15. Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors.
Leproult E; Barluenga S; Moras D; Wurtz JM; Winssinger N
J Med Chem; 2011 Mar; 54(5):1347-55. PubMed ID: 21322567
[TBL] [Abstract][Full Text] [Related]
16. Steady-state kinetic characterization of kinase activity and requirements for Mg2+ of interleukin-1 receptor-associated kinase-4.
Hekmat-Nejad M; Cai T; Swinney DC
Biochemistry; 2010 Feb; 49(7):1495-506. PubMed ID: 20104875
[TBL] [Abstract][Full Text] [Related]
17. New paradigms in anticancer therapy: targeting multiple signaling pathways with kinase inhibitors.
Faivre S; Djelloul S; Raymond E
Semin Oncol; 2006 Aug; 33(4):407-20. PubMed ID: 16890796
[TBL] [Abstract][Full Text] [Related]
18. Design and synthesis of novel tyrosine kinase inhibitors using a pharmacophore model of the ATP-binding site of the EGF-R.
Traxler P; Furet P; Mett H; Buchdunger E; Meyer T; Lydon N
J Pharm Belg; 1997; 52(2):88-96. PubMed ID: 9193132
[TBL] [Abstract][Full Text] [Related]
19. Gold nanoparticle-based electrochemical detection of protein phosphorylation.
Kerman K; Chikae M; Yamamura S; Tamiya E
Anal Chim Acta; 2007 Apr; 588(1):26-33. PubMed ID: 17386790
[TBL] [Abstract][Full Text] [Related]
20. Characterization and development of a peptide substrate-based phosphate transfer assay for the human vascular endothelial growth factor receptor-2 tyrosine kinase.
Zhao G; Peery RB; Yingling JM
Anal Biochem; 2007 Jan; 360(2):196-206. PubMed ID: 17141171
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]