These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
231 related articles for article (PubMed ID: 23045147)
1. In vitro evaluation of metabolic drug-drug interactions: a descriptive and critical commentary. Li AP Curr Protoc Toxicol; 2007; Chapter 4():Unit 4.25. PubMed ID: 23045147 [TBL] [Abstract][Full Text] [Related]
2. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5'-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography-Tandem Mass Spectrometry. Lee B; Ji HK; Lee T; Liu KH Drug Metab Dispos; 2015 Jul; 43(7):1137-46. PubMed ID: 25904760 [TBL] [Abstract][Full Text] [Related]
3. Strategies to in vitro assessment of major human CYP enzyme activities by using liquid chromatography tandem mass spectrometry. Lahoz A; Donato MT; Castell JV; Gómez-Lechón MJ Curr Drug Metab; 2008 Jan; 9(1):12-9. PubMed ID: 18220567 [TBL] [Abstract][Full Text] [Related]
4. In vitro oxidative metabolism of cajaninstilbene Acid by human liver microsomes and hepatocytes: involvement of cytochrome p450 reaction phenotyping, inhibition, and induction studies. Hua X; Peng X; Tan S; Li C; Wang W; Luo M; Fu Y; Zu Y; Smyth H J Agric Food Chem; 2014 Oct; 62(43):10604-14. PubMed ID: 25272989 [TBL] [Abstract][Full Text] [Related]
5. Study of in-vitro metabolism of selected antibiotic drugs in human liver microsomes by liquid chromatography coupled with tandem mass spectrometry. Szultka-Mlynska M; Buszewski B Anal Bioanal Chem; 2016 Nov; 408(29):8273-8287. PubMed ID: 27704178 [TBL] [Abstract][Full Text] [Related]
6. A new in vitro approach for the simultaneous determination of phase I and phase II enzymatic activities of human hepatocyte preparations. Lahoz A; Donato MT; Montero S; Castell JV; Gómez-Lechón MJ Rapid Commun Mass Spectrom; 2008; 22(2):240-4. PubMed ID: 18088071 [TBL] [Abstract][Full Text] [Related]
7. In Vitro Drug Metabolism Using Liver Microsomes. Knights KM; Stresser DM; Miners JO; Crespi CL Curr Protoc Pharmacol; 2016 Sep; 74():7.8.1-7.8.24. PubMed ID: 27636111 [TBL] [Abstract][Full Text] [Related]
8. [Liver and drug metabolism]. Mikheeva OM Eksp Klin Gastroenterol; 2011; (2):121-4. PubMed ID: 21560652 [TBL] [Abstract][Full Text] [Related]
9. Assessment of cytochrome P450 induction in human hepatocytes using the cocktail strategy plus liquid chromatography tandem mass spectrometry. Lahoz A; Donato MT; Picazo L; Castell JV; Gómez-Lechón MJ Drug Metab Lett; 2008 Aug; 2(3):205-9. PubMed ID: 19356095 [TBL] [Abstract][Full Text] [Related]
10. Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites. Wang WW; Khetani SR; Krzyzewski S; Duignan DB; Obach RS Drug Metab Dispos; 2010 Oct; 38(10):1900-5. PubMed ID: 20595376 [TBL] [Abstract][Full Text] [Related]
11. Assessment of competitive and mechanism-based inhibition by clarithromycin: use of domperidone as a CYP3A probe-drug substrate and various enzymatic sources including a new cell-based assay with freshly isolated human hepatocytes. Michaud V; Turgeon J Drug Metab Lett; 2010 Apr; 4(2):69-76. PubMed ID: 20446912 [TBL] [Abstract][Full Text] [Related]
12. In vitro profiling of the metabolism and drug-drug interaction of tofogliflozin, a potent and highly specific sodium-glucose co-transporter 2 inhibitor, using human liver microsomes, human hepatocytes, and recombinant human CYP. Yamane M; Kawashima K; Yamaguchi K; Nagao S; Sato M; Suzuki M; Honda K; Hagita H; Kuhlmann O; Poirier A; Fowler S; Funk C; Simon S; Aso Y; Ikeda S; Ishigai M Xenobiotica; 2015 Mar; 45(3):230-8. PubMed ID: 25350082 [TBL] [Abstract][Full Text] [Related]
13. Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo. Gómez-Lechón MJ; Castell JV; Donato MT Chem Biol Interact; 2007 May; 168(1):30-50. PubMed ID: 17134688 [TBL] [Abstract][Full Text] [Related]
14. Role of human liver microsomes in in vitro metabolism of drugs-a review. Asha S; Vidyavathi M Appl Biochem Biotechnol; 2010 Mar; 160(6):1699-722. PubMed ID: 19582595 [TBL] [Abstract][Full Text] [Related]
15. HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro. Lübberstedt M; Müller-Vieira U; Mayer M; Biemel KM; Knöspel F; Knobeloch D; Nüssler AK; Gerlach JC; Zeilinger K J Pharmacol Toxicol Methods; 2011; 63(1):59-68. PubMed ID: 20460162 [TBL] [Abstract][Full Text] [Related]
16. An update on metabolism studies using human hepatocytes in primary culture. Gómez-Lechón MJ; Castell JV; Donato MT Expert Opin Drug Metab Toxicol; 2008 Jul; 4(7):837-54. PubMed ID: 18624674 [TBL] [Abstract][Full Text] [Related]
17. Human hepatocytes: isolation, cryopreservation and applications in drug development. Li AP Chem Biol Interact; 2007 May; 168(1):16-29. PubMed ID: 17270162 [TBL] [Abstract][Full Text] [Related]
18. Metabolism-mediated drug interaction potential of HS-23, a new herbal drug for the treatment of sepsis in human hepatocytes and liver microsomes. Jeong HU; Lee JY; Kwon SS; Kim JH; Kim YM; Hong SW; Yeon SH; Lee SM; Cho YY; Lee HS Arch Pharm Res; 2015 Feb; 38(2):171-7. PubMed ID: 25052959 [TBL] [Abstract][Full Text] [Related]
19. The pivotal role of hepatocytes in drug discovery. Soars MG; McGinnity DF; Grime K; Riley RJ Chem Biol Interact; 2007 May; 168(1):2-15. PubMed ID: 17208208 [TBL] [Abstract][Full Text] [Related]
20. The use of human hepatocytes to investigate drug metabolism and CYP enzyme induction. Klieber S; Torreilles F; Guillou F; Fabre G Methods Mol Biol; 2010; 640():295-308. PubMed ID: 20645059 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]