BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 23052055)

  • 1. Production and function of IL-12 in islets and beta cells.
    Taylor-Fishwick DA; Weaver JR; Grzesik W; Chakrabarti S; Green-Mitchell S; Imai Y; Kuhn N; Nadler JL
    Diabetologia; 2013 Jan; 56(1):126-35. PubMed ID: 23052055
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets.
    Edén D; Siegbahn A; Mokhtari D
    Diabetologia; 2015 Nov; 58(11):2563-72. PubMed ID: 26271343
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.
    Eizirik DL; Sammeth M; Bouckenooghe T; Bottu G; Sisino G; Igoillo-Esteve M; Ortis F; Santin I; Colli ML; Barthson J; Bouwens L; Hughes L; Gregory L; Lunter G; Marselli L; Marchetti P; McCarthy MI; Cnop M
    PLoS Genet; 2012; 8(3):e1002552. PubMed ID: 22412385
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
    Hong TP; Andersen NA; Nielsen K; Karlsen AE; Fantuzzi G; Eizirik DL; Dinarello CA; Mandrup-Poulsen T
    Eur Cytokine Netw; 2000 Jun; 11(2):193-205. PubMed ID: 10903798
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.
    Heitmeier MR; Scarim AL; Corbett JA
    J Biol Chem; 1997 May; 272(21):13697-704. PubMed ID: 9153221
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Upregulation of HLA class II in pancreatic beta cells from organ donors with type 1 diabetes.
    Quesada-Masachs E; Zilberman S; Rajendran S; Chu T; McArdle S; Kiosses WB; Lee JM; Yesildag B; Benkahla MA; Pawlowska A; Graef M; Pfeiffer S; Mikulski Z; von Herrath M
    Diabetologia; 2022 Feb; 65(2):387-401. PubMed ID: 34932134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
    Bensellam M; Shi YC; Chan JY; Laybutt DR; Chae H; Abou-Samra M; Pappas EG; Thomas HE; Gilon P; Jonas JC
    Diabetologia; 2019 Dec; 62(12):2273-2286. PubMed ID: 31624901
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes.
    Chan JY; Luzuriaga J; Bensellam M; Biden TJ; Laybutt DR
    Diabetes; 2013 May; 62(5):1557-68. PubMed ID: 23274897
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes.
    Igoillo-Esteve M; Marselli L; Cunha DA; Ladrière L; Ortis F; Grieco FA; Dotta F; Weir GC; Marchetti P; Eizirik DL; Cnop M
    Diabetologia; 2010 Jul; 53(7):1395-405. PubMed ID: 20369226
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of cyclooxygenase-2 in cytokine-induced beta-cell dysfunction and damage by isolated rat and human islets.
    Heitmeier MR; Kelly CB; Ensor NJ; Gibson KA; Mullis KG; Corbett JA; Maziasz TJ
    J Biol Chem; 2004 Dec; 279(51):53145-51. PubMed ID: 15471850
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines.
    Yeung TY; Seeberger KL; Kin T; Adesida A; Jomha N; Shapiro AM; Korbutt GS
    PLoS One; 2012; 7(5):e38189. PubMed ID: 22666480
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual role of interleukin-1β in islet amyloid formation and its β-cell toxicity: Implications for type 2 diabetes and islet transplantation.
    Park YJ; Warnock GL; Ao Z; Safikhan N; Meloche M; Asadi A; Kieffer TJ; Marzban L
    Diabetes Obes Metab; 2017 May; 19(5):682-694. PubMed ID: 28058779
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic β-cell dysfunction.
    Michalska M; Wolf G; Walther R; Newsholme P
    Biosci Rep; 2010 Dec; 30(6):445-53. PubMed ID: 20178457
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress.
    Hasnain SZ; Borg DJ; Harcourt BE; Tong H; Sheng YH; Ng CP; Das I; Wang R; Chen AC; Loudovaris T; Kay TW; Thomas HE; Whitehead JP; Forbes JM; Prins JB; McGuckin MA
    Nat Med; 2014 Dec; 20(12):1417-26. PubMed ID: 25362253
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma -mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells.
    Dupraz P; Cottet S; Hamburger F; Dolci W; Felley-Bosco E; Thorens B
    J Biol Chem; 2000 Dec; 275(48):37672-8. PubMed ID: 10967106
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TLR4 triggered complex inflammation in human pancreatic islets.
    He W; Rebello O; Savino R; Terracciano R; Schuster-Klein C; Guardiola B; Maedler K
    Biochim Biophys Acta Mol Basis Dis; 2019 Jan; 1865(1):86-97. PubMed ID: 30287405
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction.
    Weaver JR; Holman TR; Imai Y; Jadhav A; Kenyon V; Maloney DJ; Nadler JL; Rai G; Simeonov A; Taylor-Fishwick DA
    Mol Cell Endocrinol; 2012 Jul; 358(1):88-95. PubMed ID: 22502743
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular production of n-3 PUFAs and reduction of n-6-to-n-3 ratios in the pancreatic beta-cells and islets enhance insulin secretion and confer protection against cytokine-induced cell death.
    Wei D; Li J; Shen M; Jia W; Chen N; Chen T; Su D; Tian H; Zheng S; Dai Y; Zhao A
    Diabetes; 2010 Feb; 59(2):471-8. PubMed ID: 19933995
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anti-diabetic action of all-trans retinoic acid and the orphan G protein coupled receptor GPRC5C in pancreatic β-cells.
    Amisten S; Mohammad Al-Amily I; Soni A; Hawkes R; Atanes P; Persaud SJ; Rorsman P; Salehi A
    Endocr J; 2017 Mar; 64(3):325-338. PubMed ID: 28228611
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interleukin-4 reduces insulin secretion in human islets from healthy but not type-2 diabetic donors.
    Westholm E; Edlund A; Karagiannopoulos A; Wendt A; Eliasson L
    Biochem Biophys Res Commun; 2023 Mar; 649():87-92. PubMed ID: 36758483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.