BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 23052231)

  • 1. L- threo -C6-pyridinium-ceramide bromide, a novel cationic ceramide, induces NADPH oxidase activation, mitochondrial dysfunction and loss in cell viability in INS 832/13 β-cells.
    Syed I; Szulc ZM; Ogretmen B; Kowluru A
    Cell Physiol Biochem; 2012; 30(4):1051-8. PubMed ID: 23052231
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1).
    Sidarala V; Veluthakal R; Syeda K; Vlaar C; Newsholme P; Kowluru A
    Biochem Pharmacol; 2015 Jun; 95(4):301-10. PubMed ID: 25881746
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of apocynin-sensitive NADPH oxidase (Nox2) activity in INS-1 832/13 cells under glucotoxic conditions.
    Mohammed AM; Kowluru A
    Islets; 2013; 5(3):129-31. PubMed ID: 23695780
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.
    Subasinghe W; Syed I; Kowluru A
    Am J Physiol Regul Integr Comp Physiol; 2011 Jan; 300(1):R12-20. PubMed ID: 20943855
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rac1-NADPH oxidase signaling promotes CD36 activation under glucotoxic conditions in pancreatic beta cells.
    Elumalai S; Karunakaran U; Lee IK; Moon JS; Won KC
    Redox Biol; 2017 Apr; 11():126-134. PubMed ID: 27912197
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phagocyte-like NADPH oxidase [Nox2] in cellular dysfunction in models of glucolipotoxicity and diabetes.
    Kowluru A; Kowluru RA
    Biochem Pharmacol; 2014 Apr; 88(3):275-83. PubMed ID: 24462914
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.
    Kowluru RA; Kowluru A; Veluthakal R; Mohammad G; Syed I; Santos JM; Mishra M
    Diabetologia; 2014 May; 57(5):1047-56. PubMed ID: 24554007
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ceramide induces mitochondrial abnormalities in insulin-secreting INS-1 cells: potential mechanisms underlying ceramide-mediated metabolic dysfunction of the beta cell.
    Veluthakal R; Palanivel R; Zhao Y; McDonald P; Gruber S; Kowluru A
    Apoptosis; 2005 Aug; 10(4):841-50. PubMed ID: 16133874
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic beta-cells.
    Syed I; Jayaram B; Subasinghe W; Kowluru A
    Biochem Pharmacol; 2010 Sep; 80(6):874-83. PubMed ID: 20493824
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Upregulation of phagocyte-like NADPH oxidase by cytokines in pancreatic beta-cells: attenuation of oxidative and nitrosative stress by 2-bromopalmitate.
    Mohammed AM; Syeda K; Hadden T; Kowluru A
    Biochem Pharmacol; 2013 Jan; 85(1):109-14. PubMed ID: 23092759
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NADPH oxidase 2-derived reactive oxygen species are involved in dysfunction and apoptosis of pancreatic β-cells induced by low density lipoprotein.
    Li M; Dou L; Jiao J; Lu Y; Guo HB; Man Y; Wang S; Li J
    Cell Physiol Biochem; 2012; 30(2):439-49. PubMed ID: 22814241
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes.
    Joseph LC; Barca E; Subramanyam P; Komrowski M; Pajvani U; Colecraft HM; Hirano M; Morrow JP
    PLoS One; 2016; 11(1):e0145750. PubMed ID: 26756466
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phagocytic NADPH oxidase links ARNO-Arf6 signaling pathway in glucose-stimulated insulin secretion from the pancreatic β-cell.
    Jayaram B; Kowluru A
    Cell Physiol Biochem; 2012; 30(6):1351-62. PubMed ID: 23095975
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NOX2, NOX4, and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 signaling and angiogenic responses in endothelial cells.
    Harel S; Mayaki D; Sanchez V; Hussain SNA
    Vascul Pharmacol; 2017 May; 92():22-32. PubMed ID: 28351775
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approaches.
    Kowluru A
    Biochem Pharmacol; 2011 Apr; 81(8):965-75. PubMed ID: 21300027
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells.
    Véret J; Coant N; Berdyshev EV; Skobeleva A; Therville N; Bailbé D; Gorshkova I; Natarajan V; Portha B; Le Stunff H
    Biochem J; 2011 Aug; 438(1):177-89. PubMed ID: 21592087
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation.
    Syed I; Kyathanahalli CN; Kowluru A
    Am J Physiol Regul Integr Comp Physiol; 2011 Mar; 300(3):R756-62. PubMed ID: 21228337
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet.
    Syed I; Kyathanahalli CN; Jayaram B; Govind S; Rhodes CJ; Kowluru RA; Kowluru A
    Diabetes; 2011 Nov; 60(11):2843-52. PubMed ID: 21911753
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NADPH oxidase 2-derived reactive oxygen species mediate FFAs-induced dysfunction and apoptosis of β-cells via JNK, p38 MAPK and p53 pathways.
    Yuan H; Zhang X; Huang X; Lu Y; Tang W; Man Y; Wang S; Xi J; Li J
    PLoS One; 2010 Dec; 5(12):e15726. PubMed ID: 21209957
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NADPH oxidase 2 plays a critical role in dysfunction and apoptosis of pancreatic β-cells induced by very low-density lipoprotein.
    Jiao J; Dou L; Li M; Lu Y; Guo HB; Man Y; Wang S; Li J
    Mol Cell Biochem; 2012 Nov; 370(1-2):103-13. PubMed ID: 22911512
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.