353 related articles for article (PubMed ID: 23054561)
1. ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
Nadkarni A; Shrivastav M; Mladek AC; Schwingler PM; Grogan PT; Chen J; Sarkaria JN
J Neurooncol; 2012 Dec; 110(3):349-57. PubMed ID: 23054561
[TBL] [Abstract][Full Text] [Related]
2. Cytotoxic effects of temozolomide and radiation are additive- and schedule-dependent.
Chalmers AJ; Ruff EM; Martindale C; Lovegrove N; Short SC
Int J Radiat Oncol Biol Phys; 2009 Dec; 75(5):1511-9. PubMed ID: 19931733
[TBL] [Abstract][Full Text] [Related]
3. Dynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control.
Golding SE; Rosenberg E; Adams BR; Wignarajah S; Beckta JM; O'Connor MJ; Valerie K
Cell Cycle; 2012 Mar; 11(6):1167-73. PubMed ID: 22370485
[TBL] [Abstract][Full Text] [Related]
4. Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
Kanai R; Rabkin SD; Yip S; Sgubin D; Zaupa CM; Hirose Y; Louis DN; Wakimoto H; Martuza RL
J Natl Cancer Inst; 2012 Jan; 104(1):42-55. PubMed ID: 22173583
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of GSH synthesis potentiates temozolomide-induced bystander effect in glioblastoma.
Kohsaka S; Takahashi K; Wang L; Tanino M; Kimura T; Nishihara H; Tanaka S
Cancer Lett; 2013 Apr; 331(1):68-75. PubMed ID: 23246370
[TBL] [Abstract][Full Text] [Related]
6. Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts.
Gupta SK; Mladek AC; Carlson BL; Boakye-Agyeman F; Bakken KK; Kizilbash SH; Schroeder MA; Reid J; Sarkaria JN
Clin Cancer Res; 2014 Jul; 20(14):3730-41. PubMed ID: 24838527
[TBL] [Abstract][Full Text] [Related]
7. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
Caporali S; Falcinelli S; Starace G; Russo MT; Bonmassar E; Jiricny J; D'Atri S
Mol Pharmacol; 2004 Sep; 66(3):478-91. PubMed ID: 15322239
[TBL] [Abstract][Full Text] [Related]
8. Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth.
Ramirez YP; Mladek AC; Phillips RM; Gynther M; Rautio J; Ross AH; Wheelhouse RT; Sakaria JN
Mol Cancer Ther; 2015 Jan; 14(1):111-9. PubMed ID: 25351918
[TBL] [Abstract][Full Text] [Related]
9. Human monocytes undergo excessive apoptosis following temozolomide activating the ATM/ATR pathway while dendritic cells and macrophages are resistant.
Bauer M; Goldstein M; Heylmann D; Kaina B
PLoS One; 2012; 7(6):e39956. PubMed ID: 22768182
[TBL] [Abstract][Full Text] [Related]
10. The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.
Li Y; Yang DQ
Mol Cancer Ther; 2010 Jan; 9(1):113-25. PubMed ID: 20053781
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells.
Korwek Z; Sewastianik T; Bielak-Zmijewska A; Mosieniak G; Alster O; Moreno-Villanueva M; Burkle A; Sikora E
DNA Repair (Amst); 2012 Nov; 11(11):864-73. PubMed ID: 23058634
[TBL] [Abstract][Full Text] [Related]
12. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
[TBL] [Abstract][Full Text] [Related]
13. Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion.
Golding SE; Rosenberg E; Valerie N; Hussaini I; Frigerio M; Cockcroft XF; Chong WY; Hummersone M; Rigoreau L; Menear KA; O'Connor MJ; Povirk LF; van Meter T; Valerie K
Mol Cancer Ther; 2009 Oct; 8(10):2894-902. PubMed ID: 19808981
[TBL] [Abstract][Full Text] [Related]
14. Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells.
Filippi-Chiela EC; Thomé MP; Bueno e Silva MM; Pelegrini AL; Ledur PF; Garicochea B; Zamin LL; Lenz G
BMC Cancer; 2013 Mar; 13():147. PubMed ID: 23522185
[TBL] [Abstract][Full Text] [Related]
15. ATM-dependent hyper-radiosensitivity in mammalian cells irradiated by heavy ions.
Xue L; Yu D; Furusawa Y; Cao J; Okayasu R; Fan S
Int J Radiat Oncol Biol Phys; 2009 Sep; 75(1):235-43. PubMed ID: 19695441
[TBL] [Abstract][Full Text] [Related]
16. Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response.
Golding SE; Rosenberg E; Neill S; Dent P; Povirk LF; Valerie K
Cancer Res; 2007 Feb; 67(3):1046-53. PubMed ID: 17283137
[TBL] [Abstract][Full Text] [Related]
17. Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines.
Beier D; Schriefer B; Brawanski K; Hau P; Weis J; Schulz JB; Beier CP
J Neurooncol; 2012 Aug; 109(1):45-52. PubMed ID: 22544650
[TBL] [Abstract][Full Text] [Related]
18. Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression.
Lan F; Yang Y; Han J; Wu Q; Yu H; Yue X
Int J Oncol; 2016 Feb; 48(2):559-68. PubMed ID: 26648123
[TBL] [Abstract][Full Text] [Related]
19. PARP‑1 inhibition sensitizes temozolomide‑treated glioblastoma cell lines and decreases drug resistance independent of MGMT activity and PTEN proficiency.
Montaldi AP; Lima SCG; Godoy PRDV; Xavier DJ; Sakamoto-Hojo ET
Oncol Rep; 2020 Nov; 44(5):2275-2287. PubMed ID: 32901889
[TBL] [Abstract][Full Text] [Related]
20. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
Hickson I; Zhao Y; Richardson CJ; Green SJ; Martin NM; Orr AI; Reaper PM; Jackson SP; Curtin NJ; Smith GC
Cancer Res; 2004 Dec; 64(24):9152-9. PubMed ID: 15604286
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]