These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 23054708)

  • 21. Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines.
    Batra S; Sabnis YA; Rosenthal PJ; Avery MA
    Bioorg Med Chem; 2003 May; 11(10):2293-9. PubMed ID: 12713840
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi.
    Greenbaum DC; Mackey Z; Hansell E; Doyle P; Gut J; Caffrey CR; Lehrman J; Rosenthal PJ; McKerrow JH; Chibale K
    J Med Chem; 2004 Jun; 47(12):3212-9. PubMed ID: 15163200
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of α-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum.
    Weldon DJ; Shah F; Chittiboyina AG; Sheri A; Chada RR; Gut J; Rosenthal PJ; Shivakumar D; Sherman W; Desai P; Jung JC; Avery MA
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1274-9. PubMed ID: 24507921
    [TBL] [Abstract][Full Text] [Related]  

  • 24. An endoperoxide-based hybrid approach to deliver falcipain inhibitors inside malaria parasites.
    Oliveira R; Newton AS; Guedes RC; Miranda D; Amewu RK; Srivastava A; Gut J; Rosenthal PJ; O'Neill PM; Ward SA; Lopes F; Moreira R
    ChemMedChem; 2013 Sep; 8(9):1528-36. PubMed ID: 23853126
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Comparison of efficacies of cysteine protease inhibitors against five strains of Plasmodium falciparum.
    Singh A; Rosenthal PJ
    Antimicrob Agents Chemother; 2001 Mar; 45(3):949-51. PubMed ID: 11181388
    [TBL] [Abstract][Full Text] [Related]  

  • 26. De novo design of 7-aminocoumarin derivatives as novel falcipain-3 inhibitors.
    Chintakrindi AS; Shaikh MS; Coutinho EC
    J Mol Model; 2012 Apr; 18(4):1481-93. PubMed ID: 21785935
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis and antimalarial effects of phenothiazine inhibitors of a Plasmodium falciparum cysteine protease.
    Domínguez JN; López S; Charris J; Iarruso L; Lobo G; Semenov A; Olson JE; Rosenthal PJ
    J Med Chem; 1997 Aug; 40(17):2726-32. PubMed ID: 9276017
    [TBL] [Abstract][Full Text] [Related]  

  • 28. In silico identification of noncompetitive inhibitors targeting an uncharacterized allosteric site of falcipain-2.
    Hernández González JE; Salas-Sarduy E; Hernández Alvarez L; Barreto Gomes DE; Pascutti PG; Oostenbrink C; Leite VBP
    J Comput Aided Mol Des; 2021 Oct; 35(10):1067-1079. PubMed ID: 34617191
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Antimalarial activity of azadipeptide nitriles.
    Löser R; Gut J; Rosenthal PJ; Frizler M; Gütschow M; Andrews KT
    Bioorg Med Chem Lett; 2010 Jan; 20(1):252-5. PubMed ID: 19913414
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Combating multi-drug resistant malaria parasite by inhibiting falcipain-2 and heme-polymerization: Artemisinin-peptidyl vinyl phosphonate hybrid molecules as new antimalarials.
    Aratikatla EK; Kalamuddin M; Rana KC; Datta G; Asad M; Sundararaman S; Malhotra P; Mohmmed A; Bhattacharya AK
    Eur J Med Chem; 2021 Aug; 220():113454. PubMed ID: 33901900
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthetic compounds from an in house library as inhibitors of falcipain-2 from Plasmodium falciparum.
    Bertoldo JB; Chiaradia-Delatorre LD; Mascarello A; Leal PC; Cordeiro MN; Nunes RJ; Sarduy ES; Rosenthal PJ; Terenzi H
    J Enzyme Inhib Med Chem; 2015 Apr; 30(2):299-307. PubMed ID: 24964346
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cloning and characterization of Plasmodium falciparum cysteine protease, falcipain-2B.
    Jeong JJ; Kumar A; Hanada T; Seo PS; Li X; Hanspal M; Chishti AH
    Blood Cells Mol Dis; 2006; 36(3):429-35. PubMed ID: 16595182
    [TBL] [Abstract][Full Text] [Related]  

  • 33. 2-(3,4-dihydro-4-oxothieno[2,3-d]pyrimidin-2-ylthio) acetamides as a new class of falcipain-2 inhibitors. 3. design, synthesis and biological evaluation.
    Zhu J; Chen T; Liu J; Ma R; Lu W; Huang J; Li H; Li J; Jiang H
    Molecules; 2009 Feb; 14(2):785-97. PubMed ID: 19223827
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.
    Desai PV; Patny A; Sabnis Y; Tekwani B; Gut J; Rosenthal P; Srivastava A; Avery M
    J Med Chem; 2004 Dec; 47(26):6609-15. PubMed ID: 15588096
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Antimalarial activities of novel synthetic cysteine protease inhibitors.
    Lee BJ; Singh A; Chiang P; Kemp SJ; Goldman EA; Weinhouse MI; Vlasuk GP; Rosenthal PJ
    Antimicrob Agents Chemother; 2003 Dec; 47(12):3810-4. PubMed ID: 14638488
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.
    Hansen G; Heitmann A; Witt T; Li H; Jiang H; Shen X; Heussler VT; Rennenberg A; Hilgenfeld R
    Structure; 2011 Jul; 19(7):919-29. PubMed ID: 21742259
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro.
    Micale N; Cinellu MA; Maiore L; Sannella AR; Severini C; Schirmeister T; Gabbiani C; Messori L
    J Inorg Biochem; 2011 Dec; 105(12):1576-9. PubMed ID: 22071081
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.
    Micale N; Ettari R; Schirmeister T; Evers A; Gelhaus C; Leippe M; Zappalà M; Grasso S
    Bioorg Med Chem; 2009 Sep; 17(18):6505-11. PubMed ID: 19709887
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Identification of diverse natural products as falcipain-2 inhibitors through structure-based virtual screening.
    Wang L; Zhang S; Zhu J; Zhu L; Liu X; Shan L; Huang J; Zhang W; Li H
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1261-4. PubMed ID: 24530004
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Antimalarial activity of thiosemicarbazones and purine derived nitriles.
    Mallari JP; Guiguemde WA; Guy RK
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3546-9. PubMed ID: 19447616
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.